Search Vacation Homes in Wykoff

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
12 Sep - 14 Sep
In two weeks
19 Sep - 21 Sep
In one month
3 Oct - 5 Oct
In two months
31 Oct - 2 Nov

Vacation Homes in Wykoff

Our top choices for Wykoff vacation homes

The Hen House Retreat - A Comfortable Place to Roost
Exterior detail

The Hen House Retreat - A Comfortable Place to Roost

9.6 out of 10, Exceptional, (84)
"We enjoyed taking it easy watching some movies and crafting together for the weekend."
The price is SAR 608
SAR 745 total
includes taxes & fees
2 Sep - 3 Sep
The Hen House Retreat - A Comfortable Place to Roost
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
Fridge, microwave, oven, stovetop

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom

10.0 out of 10, Exceptional, (56)
"This was the perfect place for us to stay, everything was comfortable and had just what we needed. Not far from Mayo Clinic. "
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Fridge, microwave, oven, stovetop

Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic

10.0 out of 10, Exceptional, (34)
"This home is Central to the Mayo clinic The home is very nice and clean with everything you could possibly need for your stay. We would be back in a few months and definitely be staying here"
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Fridge, microwave, oven, stovetop

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (93)
"perfect location perfect house. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
"Walden Pond" Adventure Amidst 44 Private Acres
Interior

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (134)
"Beautiful accommodations, great communication, wonderful hiking, campfires and smores! Our third visit and we love it every time! "
"Walden Pond" Adventure Amidst 44 Private Acres
Red Juniper House // 4BR, 2.5 Bath, Large Yard, Pet Friendly, 3mi to Mayo Clinic
Private kitchen

Red Juniper House // 4BR, 2.5 Bath, Large Yard, Pet Friendly, 3mi to Mayo Clinic

10.0 out of 10, Exceptional, (8)
"Great option for a family! Loved our stay!"
Red Juniper House // 4BR, 2.5 Bath, Large Yard, Pet Friendly, 3mi to Mayo Clinic
Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio
Exterior detail

Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio

10.0 out of 10, Exceptional, (8)
"A lovely home that was so comfortable for us to stay in "
Charming 4-bedroom house with 3 king/1 full beds, 2 full baths, AC, Wifi, Patio
The Best of Southwest Rochester, MN
Living area

The Best of Southwest Rochester, MN

10.0 out of 10, Exceptional, (1)
"The house was lovely and impeccably clean and well stocked with essentials and bonus coffee, snacks and candies. Check in was clear and easy. Thank you, Sarah!"
The Best of Southwest Rochester, MN
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Interior

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

9.0 out of 10, Wonderful, (16)
"Overall a good stay. The property was clean and mostly updated, but the home was very old. The foundation was slanted so much that items would roll off the table quickly and you could feel the slant when walking through the house."
The price is SAR 356
SAR 1,002 total
includes taxes & fees
7 Sep - 8 Sep
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Silver Lake Oasis
Property grounds

Silver Lake Oasis

9.6 out of 10, Exceptional, (38)
"A nice little place, well kept and just as advertised."
Silver Lake Oasis
Lots of charm and only blocks away from the Root River and Bike trails
TV, DVD player, books

Lots of charm and only blocks away from the Root River and Bike trails

9.8 out of 10, Exceptional, (27)
"Had a great time here with my family of 5, including twin toddlers. Plenty of space and even had a children's play room stocked with toys that the kids loved!"
Lots of charm and only blocks away from the Root River and Bike trails
Quaint home with large yard, pet friendly, bike storage right off the trailhead
Dining

Quaint home with large yard, pet friendly, bike storage right off the trailhead

10.0 out of 10, Exceptional, (2)
"Great location for our girl's bicycling trip. Nice space to chill and relax. Great showers and beds were comfortable after our long days of adventures. Would highly recommend this house to others. "
Quaint home with large yard, pet friendly, bike storage right off the trailhead
New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)
3 bedrooms, iron/ironing board, WiFi, bed sheets

New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)

9.8 out of 10, Exceptional, (41)
"Communication was fantastic, lovely house! "
New Listing! Bella Casa! Whole house downtown Rochester. (Near Mayo Clinic)
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Dining

Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester

10.0 out of 10, Exceptional, (2)
"We stayed here for a quick night before heading into WI to visit family! We loved how cozy and pet friendly it was! We will stay again! "
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester
Within walking distance of all the amenities! Bike the trail~ float the river
Exterior

Within walking distance of all the amenities! Bike the trail~ float the river

10.0 out of 10, Exceptional, (28)
"We all talked about how clean and relaxing the home was…very clean, updated, well stocked and awesome location. "
Within walking distance of all the amenities! Bike the trail~ float the river
SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO
Interior

SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO

SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO
Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets
Exterior

Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets

9.6 out of 10, Exceptional, (4)
"Very cute and well maintained. We would definitely stay again. "
Lux 3BR Cozy Nook I Mins to Mayo & Dwtwn I Pets
Magical Nest Hideaway
Exterior

Magical Nest Hideaway

10.0 out of 10, Exceptional, (123)
"Stayed a couple days. Nice location and friendly owners. "
Magical Nest Hideaway
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Fridge, microwave, oven, stovetop

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

10.0 out of 10, Exceptional, (41)
"We stayed here a second time for the Mayo Clinic, Alex and Emily are the best hosts we’ve ever had at a VRBO"
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Spacious and clean house near airport, theater and shopping center
Fridge, microwave, oven, stovetop

Spacious and clean house near airport, theater and shopping center

10.0 out of 10, Exceptional, (41)
"Great property, great fun, thank you!"
Spacious and clean house near airport, theater and shopping center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Wykoff Hotel Reviews