Find hotels in Upstate South Carolina, SC from SAR 229
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Pet friendly
Apartment
Apart hotel
Family friendly
Waterpark
Farm
Cabin
Condo
Villa
Check prices for these dates
Tonight
18 Aug - 19 AugTomorrow
19 Aug - 20 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugOur top choices for Upstate South Carolina hotels
1. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
Nancy
SAR 311
SAR 342 total
includes taxes & fees
30 Aug - 31 Aug
2. Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
Robert
SAR 366
SAR 415 total
includes taxes & fees
30 Aug - 31 Aug
3. Drury Inn & Suites Greenville
Drury Inn & Suites GreenvilleGreenville
Gohan
SAR 432
SAR 475 total
includes taxes & fees
30 Aug - 31 Aug
4. Hilton Greenville
Hilton GreenvilleGreenville
Gildardo
SAR 385
SAR 436 total
includes taxes & fees
5 Sep - 6 Sep
5. Courtyard by Marriott Greenville Mauldin
Courtyard by Marriott Greenville MauldinGreenville
sarah
SAR 447
SAR 491 total
includes taxes & fees
23 Aug - 24 Aug
6. DoubleTree by Hilton Greenville Woodruff Road
DoubleTree by Hilton Greenville Woodruff RoadGreenville
JOANNA
SAR 428
SAR 485 total
includes taxes & fees
30 Aug - 31 Aug
7. Hampton Inn & Suites Greenville-Downtown-RiverPlace
Hampton Inn & Suites Greenville-Downtown-RiverPlaceGreenville Downtown
Layne
SAR 557
SAR 631 total
includes taxes & fees
3 Sep - 4 Sep
8. Comfort Inn Greenville - Haywood Mall
Comfort Inn Greenville - Haywood MallGreenville
Brittney
SAR 321
SAR 364 total
includes taxes & fees
23 Aug - 24 Aug
9. Hilton Garden Inn Greenville
Hilton Garden Inn GreenvilleGreenville
Robert
SAR 336
SAR 380 total
includes taxes & fees
6 Sep - 7 Sep
10. Homewood Suites by Hilton Greenville Downtown
Homewood Suites by Hilton Greenville DowntownGreenville Downtown
Brandon
SAR 520
SAR 589 total
includes taxes & fees
7 Sep - 8 Sep
11. Embassy Suites by Hilton Greenville Downtown Riverplace
Embassy Suites by Hilton Greenville Downtown RiverplaceGreenville Downtown
LATOYA
SAR 551
SAR 624 total
includes taxes & fees
8 Sep - 9 Sep
12. SpringHill Suites by Marriott Greenville Downtown
SpringHill Suites by Marriott Greenville DowntownGreenville Downtown
Douglas
SAR 515
SAR 583 total
includes taxes & fees
31 Aug - 1 Sep
13. Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
Teresa
SAR 541
SAR 589 total
includes taxes & fees
20 Aug - 21 Aug
14. Holiday Inn Express & Suites Greenville - Taylors by IHG
Holiday Inn Express & Suites Greenville - Taylors by IHGGreenville
John
SAR 413
SAR 468 total
includes taxes & fees
23 Aug - 24 Aug
15. Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
Carole
SAR 316
SAR 348 total
includes taxes & fees
23 Aug - 24 Aug
16. Hyatt Place Greenville Downtown
Hyatt Place Greenville DowntownGreenville Downtown
Melanie
SAR 491
SAR 557 total
includes taxes & fees
7 Sep - 8 Sep
17. Hampton Inn Greenville I-385 - Woodruff Rd.
Hampton Inn Greenville I-385 - Woodruff Rd.Greenville
Anne
SAR 382
SAR 433 total
includes taxes & fees
7 Sep - 8 Sep
18. Comfort Suites Greenville Airport
Comfort Suites Greenville AirportGreenville
Chandler
SAR 370
SAR 419 total
includes taxes & fees
13 Sep - 14 Sep
19. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Microtel Inn & Suites by Wyndham Greenville / Woodruff RdGreenville
Steven
SAR 287
SAR 316 total
includes taxes & fees
7 Sep - 8 Sep
20. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
Cole
SAR 277
SAR 314 total
includes taxes & fees
7 Sep - 8 Sep
Vacation Rentals in Upstate South Carolina
Apartment
Mint House Greenville Downtown by Kasa
Mint House Greenville Downtown by KasaGreenville Downtown
"Love the location. Room was great."
Aparthotel
stayAPT Suites Greenville-Haywood Mall
stayAPT Suites Greenville-Haywood MallGreenville
"All the staff from front desk to housekeeping were excellent, friendly and helpful. If looking for rooms with a feel like home StayApt is what you are looking for. I recommend reserving here great place if you want to cook your own meals"
Cottage
Claires Cottage ~ 4 Mi to Downtown Greenville!
Claires Cottage ~ 4 Mi to Downtown Greenville!Greenville
"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."
Aparthotel
The Station by Compo Hotels
The Station by Compo HotelsTravelers Rest
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
Cabin
Carolina Camp Cedar
Carolina Camp CedarPickens
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
"Very relaxing, clean environment. Felt safe and welcoming."
Aparthotel
Landing Apartments - Lyman
Landing Apartments - LymanLyman
"Great room that was nice and clean. Smooth check-in."
Mobile Home
Carolina Landing RV Resort - Caravan Park
Carolina Landing RV Resort - Caravan ParkFair Play
"Very nice stay with friendly staff"
Cottage
Cozy Greenville Bungalow ~ 2 Mi to Downtown!
Cozy Greenville Bungalow ~ 2 Mi to Downtown!Greenville
"Amazing place. Great host. "
Cottage
Stay at Jos Taylor Retreat: 9 Mi to Greenville!
Stay at Jos Taylor Retreat: 9 Mi to Greenville!Taylors
"This rental is a time capsule that takes you back to Grandma and Grandpa's home. The owner is great to communicate with, as well as their property manager. Quaint older furniture, complete with blankets on the couches. There's all you need to cook and even a great cast-iron frying pan. I wish we had stayed here longer."
Cottage
Families Welcome, Fenced Yard: Inviting Greer Home
Families Welcome, Fenced Yard: Inviting Greer HomeGreer
"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."
Apartment
Serene Travelers Rest Apartment: 7 Mi to Downtown!
Serene Travelers Rest Apartment: 7 Mi to Downtown!Travelers Rest
"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "
Cottage
1 Mi to Downtown Greer: Family Home w/ Gazebo!
1 Mi to Downtown Greer: Family Home w/ Gazebo!Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
Cottage
Serene Cabin w/ Pond & Creek on South Saluda River
Serene Cabin w/ Pond & Creek on South Saluda RiverCleveland
"I chose this cabin due to its close proximity to the pretty place chapel. The property was BEAUTIFUL and tucked away. The silence and change of scenery was well needed and felt like we were at home. I honestly don’t have enough good things to say about the host Mr. Steve and his generosity and professionalism!"
Cottage
4 Seasons of Fun! Walhalla Home w/ Spacious Yard!
4 Seasons of Fun! Walhalla Home w/ Spacious Yard!Walhalla
"The house was perfect for our group for our golf trip. We had one minor issue and we were able to speak to the host and they had someone to correct it quickly so that it didn’t disrupt our trip in any way. Place was clean, peaceful, with great hosts."
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Upstate South Carolina attractions
Clemson University
9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
Photo by Karyn Thompson
Fred W. Symmes Chapel
9.8/10 (29 reviews)
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Memorial Stadium
9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.
See all hotels in Upstate South Carolina
Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews
Hilton Greenville
10/10 Excellent
"Great location, staff, condition. Thanks. I’ll be back"
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
"Loved it. Always lovely and the staff are wonderful. Clean and great breakfast as usual."
Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
"This was the most enjoyable stay I’ve had in Clemson! Everything was great. I will stay here again next year!"
The Shepherd Hotel Downtown Clemson
10/10 Excellent
"N/a"
Inn @ Clemson
8/10 Good
"Close to campus, staff was amazing, amenities were ehh, breakfast was small, gym was out of service."
Comfort Inn & Suites Clemson - University Area
10/10 Excellent
"Stayed during Clemson move in and it was great. Very reasonable price, clean room and good breakfast. Also super close to campus!"
Hotel Hartness
10/10 Excellent
"Amazing!"
Best Western Plus Greenville I-385 Inn & Suites
8/10 Good
"Checking in was odd because we booked ahead of time: but still required a card to check in. WiFi password was confusing until we figured out, beds were a little firm for my liking but the pillows were great. Room was clean and housekeeping was nice; parking kinda sucks tho. We didn’t eat the breakfast or use the pool/fitness center. We typically enjoyed our time in the city. But, it’s very centrally located to a lot, most things were only 10 mins away!"
Grand Bohemian Lodge Greenville, Autograph Collection
10/10 Excellent
"It was amazing! Check in took a while though. Everyone was waiting around in the lobby for their rooms. We got ours just before 4 pm -which was tight for our 5:30 pm event."
More cheap stays in Upstate South Carolina
Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
SAR 227
SAR 249 total
30 Aug - 31 Aug
includes taxes & fees
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
SAR 311
SAR 342 total
30 Aug - 31 Aug
includes taxes & fees
9.2/10 Wonderful! (1,562 reviews)
Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
SAR 321
SAR 364 total
23 Aug - 24 Aug
includes taxes & fees
8.2/10 Very Good! (1,003 reviews)
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
161 Sha Ln Spartanburg SC
SAR 355
SAR 394 total
30 Aug - 31 Aug
includes taxes & fees
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
SAR 380
SAR 422 total
22 Aug - 23 Aug
includes taxes & fees
8/10 Very Good! (1,035 reviews)
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
SAR 409
SAR 508 total
20 Aug - 21 Aug
includes taxes & fees
Hotels in Upstate South Carolina with star-rating
4 Star Hotels
29 properties
3 Star Hotels
195 properties
2 Star Hotels
144 properties
