Top 10 Hotels in Upstate South Carolina, SC from SAR 234 - Competitive Prices

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Our top choices for Upstate South Carolina hotels

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A pool area with lounge chairs and a sign for Best Western Plus.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

1. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Stephanie

SAR 291

SAR 321 total

includes taxes & fees

25 Oct - 26 Oct

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

Electric vehicle charging stations along a sidewalk with a building in the background.

A golf course with multiple golf carts parked in a line.

A conference room with a long table, chairs, and a carpeted floor.

2. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Ethan

SAR 397

SAR 450 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A fitness center with treadmills, elliptical machines, and a red exercise ball.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

3. Drury Inn & Suites Greenville

Greenville

David

SAR 432

SAR 475 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with hanging light fixtures and bar seating.

A modern hotel room with a large desk, a comfortable sofa, and a bed.

A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

A modern bar area with a central island, bar stools, and overhead lighting.

4. DoubleTree by Hilton Greenville Woodruff Road

Greenville

Jeffery

SAR 417

SAR 473 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio area with a fire feature, wicker furniture, and potted plants.

A conference room with rows of chairs, a flat-screen TV, a door, and a carpeted floor.

A row of Tesla electric vehicle charging stations.

A Hilton Garden Inn with a central entrance, multiple floors, and a brick facade.

5. Hilton Garden Inn Greenville

Greenville

Leroy

SAR 366

SAR 415 total

includes taxes & fees

31 Oct - 1 Nov

A hotel with a stone facade, multiple windows, and a sign indicating it's a Wyndham hotel.

A hotel room with a bed, a television, a window with curtains, and a wardrobe.

A room with a wall-mounted ATM, decorative wall panels, a window with red curtains, and a tiled floor.

A compact living space with a kitchenette, a flat-screen TV, a sofa, and a bed with a patterned cover.

6. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Greenville

Terry

SAR 268

SAR 295 total

includes taxes & fees

1 Nov - 2 Nov

A modern outdoor seating area with a glass-top coffee table, blue sofas, and orange patterned cushions.

A modern lobby with a blue sofa, teal armchairs, hanging lights, and a seating area with round chairs.

A snack bar with a variety of packaged foods and beverages, a refrigerated display case, and a counter with a sign that reads 'This and that and then some.'

7. Tru by Hilton Greenville Woodruff Road

Greenville

semhar

SAR 395

SAR 471 total

includes taxes & fees

3 Nov - 4 Nov

A modern hotel lobby with a bar area, seating, and a patterned floor.

A hotel entrance with a welcoming sign, a covered walkway, and a landscaped area with benches and flowers.

A modern living room with a sofa, armchairs, a coffee table, and a patterned rug.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

8. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Greenville

George

SAR 349

SAR 396 total

includes taxes & fees

8 Nov - 9 Nov

A spacious hotel lobby with a central bar area, seating arrangements, and large windows providing natural light.

A conference room with a large flat-screen TV, multiple tables with chairs, and water bottles on each table.

A modern lounge area with green upholstered seating, a coffee table, and pendant lighting.

A hotel room with a bed, desk, chair, TV, and a window with a geometric pattern.

9. Holiday Inn Greenville - Woodruff Road by IHG

Greenville

Diane

SAR 387

SAR 426 total

includes taxes & fees

8 Nov - 9 Nov

An outdoor patio with a modern design, featuring a seating area with sofas and a fire pit, surrounded by plants and under a pergola with hanging lights.

A modern office space with a wooden partition, two desks with computers, green chairs, and a glass door leading outside.

A modern interior with a bar area, seating, and a staircase.

A bar area with a central island, multiple bar stools, hanging spherical light fixtures, and a stone pillar.

10. SpringHill Suites by Marriott Greenville Downtown

Greenville Downtown

Douglas

SAR 548

SAR 621 total

includes taxes & fees

1 Nov - 2 Nov

A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.

A La Quinta hotel with a covered outdoor seating area, stone pillars, and a parking lot.

A modern living room with a fireplace, a flat-screen TV, and comfortable seating.

A modern kitchen with a refrigerator, coffee machine, and various food items.

11. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

Greenville

Lissette

SAR 383

SAR 434 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel lobby with a reception desk, seating area, and a decorative wall.

A multi-story hotel with a modern design, featuring a mix of glass and brick facades, and a parking area with autumn-colored trees.

A hotel room with a large bed, a TV, a desk, and a view of the city through large windows.

12. Hyatt Place Greenville Downtown

Greenville Downtown

Tamara

SAR 458

SAR 519 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel room with a large bed, a desk, and a seating area with chairs and a table.

A hotel room with a large bed, a television on a dresser, a nightstand with a lamp, and a window with curtains.

A hotel pool area with lounge chairs, a flag, and a sunset view.

A cafe with a checkered floor, wooden cabinets, and hanging pendant lights.

13. Hampton Inn Greenville I-385 - Woodruff Rd.

Greenville

Joseph

SAR 382

SAR 433 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with a wooden pergola, barbecue grill, and seating.

An indoor swimming pool with a brick wall backdrop, a poolside area with tables and chairs, and a clear pool edge.

A modern hotel lobby with a seating area featuring sofas and round tables, large windows, and a decorative wooden panel.

A modern building with large windows and a brick facade at a street corner.

14. Homewood Suites by Hilton Greenville Downtown

Greenville Downtown

Michael

SAR 551

SAR 625 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, seating area, and a view of the outdoors.

A hotel room with a large bed, a TV, a desk, and a chair.

A stone building with a sign for 'Sweets' and outdoor seating with blue umbrellas.

A modern interior with a round table and red chairs, large windows with a view of greenery, and a blue door.

15. Holiday Inn Express & Suites Greenville - Downtown by IHG

Greenville Downtown

Robyn

SAR 545

SAR 599 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with modern furniture, a chandelier, and potted plants.

A bar with a white countertop, multiple bar stools, and shelves stocked with bottles.

16. Hilton Greenville

Greenville

Edward

SAR 404

SAR 458 total

includes taxes & fees

1 Nov - 2 Nov

A circular outdoor seating area with a fire pit, surrounded by sofas and chairs, in front of a multi-story building.

A Courtyard by Marriott hotel with a modern design, featuring a covered entrance and landscaped garden.

A hotel room with two beds, a desk with a computer, a chair, and a large window with curtains.

A modern bar area with a curved counter, bar stools, and a wine glass.

17. Courtyard by Marriott Greenville Haywood Mall

Greenville

Kimberly

SAR 411

SAR 466 total

includes taxes & fees

19 Oct - 20 Oct

A modern lobby with a reception desk, seating area, and a kitchen in the background.

A modern hotel lobby with a large digital display, seating areas, and a view of the outdoors.

A hotel exterior with large windows, outdoor seating, and potted plants.

A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

18. Courtyard by Marriott Greenville Downtown

Greenville Downtown

Susan

SAR 504

SAR 571 total

includes taxes & fees

25 Oct - 26 Oct

A Comfort Suites hotel with a symmetrical facade, multiple windows, and a central entrance.

An indoor swimming pool with clear lane markings, a sunroof, and lounge chairs along the poolside.

A spacious lobby with multiple seating areas, including sofas and chairs, and a reception desk.

A hotel room with a bed, a sofa, two ottomans, a lamp, and three framed pictures on the wall.

19. Comfort Suites Piedmont - Greenville South

Piedmont

Stephanie

SAR 324

SAR 360 total

includes taxes & fees

31 Oct - 1 Nov

An outdoor patio with a stone fire feature, seating, and a view of the city skyline.

A Courtyard by Marriott hotel with a modern facade, a covered entrance, and landscaped flower beds.

A modern bar area with a wooden counter, a digital menu board, and a variety of liquor bottles.

A modern lounge area with comfortable seating, a round table, and a large screen.

20. Courtyard by Marriott Greenville Mauldin

Greenville

Leticia

SAR 412

SAR 453 total

includes taxes & fees

18 Oct - 19 Oct

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Vacation Rentals in Upstate South Carolina

Aparthotel

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

stayAPT Suites Greenville-Haywood Mall

Greenville

"Everything was great"

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Excellent location for our trip. Very clean, had everything we needed."

Cabin

A swimming pool with lounge chairs and a covered area with tables and chairs.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A covered porch with a welcome mat, two black Adirondack chairs, and a bench.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A bedroom with a wooden bed, a dresser, a mirror, a window with blinds, and a door leading to a bathroom.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Cabin

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Beautiful cabin, attentive hosts, and an overall great stay. I would definitely go back."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A rustic cabin with a porch, wooden steps, and a picnic table.

A cozy cabin interior with a wooden interior, a sofa, a television on a wooden stand, and a sign on the wall.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

A modern kitchen with a built-in oven, a coffee maker, and a small dining area with two chairs and a table.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Apartment

A large house with a spacious driveway and a pond in the background.

A spacious living room with a high ceiling, a large leather sofa, a flat-screen TV, and a wooden coffee table.

A modern kitchen with a central island, wooden cabinets, and a dining area with bar stools.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A round table with a white tablecloth, surrounded by chairs, set up for a meal.

A kitchen with granite countertops, stainless steel appliances, and dark wooden cabinets.

A living room with a fireplace, a television, a leather sofa, a red armchair, and a desk with drawers.

A single-story house with a garage, a front lawn, and a driveway.

Stay at Jos Taylor Retreat: 9 Mi to Greenville!

Taylors

"This rental is a time capsule that takes you back to Grandma and Grandpa's home. The owner is great to communicate with, as well as their property manager. Quaint older furniture, complete with blankets on the couches. There's all you need to cook and even a great cast-iron frying pan. I wish we had stayed here longer."

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A white door with a brass knocker, a white bench, a potted plant, and a wicker basket outside a house with a brick foundation and a window with blinds.

A dining area with a wooden table and grey upholstered chairs, a large mirror, and a painting on the wall.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.

A covered deck with wooden flooring, outdoor furniture, and a barbecue grill.

A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.

A modern kitchen with stainless steel appliances, white cabinetry, and a central island.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Seneca

"The best, perfect "

Cottage

A patio area with a red umbrella, metal chairs, a table, and a fire pit.

A cozy living room with a television, a fireplace, a ceiling fan, and a large rug.

A covered porch with wooden flooring, a ceiling fan, and a view of the outdoors.

A wooden deck with a railing overlooking a calm river, surrounded by lush greenery.

Cleveland Home w/ South Saluda Fishing Access

Cleveland

"This was a fishing trip that myself and a couple of my friends went on. The cabin was exactly as described in the listing and then some. Very clean and had every amenity you could think of. The host lives next door and went above and beyond making sure we had everything we needed and were comfortable. He even lent us his state pass to get into the parks and supplied his vast knowledge of where and what to use for fishing in the creeks. Will definitely be going back sometime in the near future."

Cottage

A cozy bedroom with a bed, a nightstand, a lamp, a small table, a window, and a Christmas tree.

A kitchen with wooden cabinets, a microwave, a stove, and a refrigerator.

A dining area with a wooden table, chairs, and a ceiling fan.

A home interior with a metal shelf unit displaying various items, a hallway with wooden flooring, and a door leading to another room.

8 Mi to Clemson: Peaceful Family Home w/ Yard

Seneca

"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Top Upstate South Carolina Hotel Reviews

Hotel Hartness

10/10 Excellent

"Beautiful property. Exceeded my expectations."

Hyatt Place Greenville Downtown

10/10 Excellent

"Great location in downtown Greenville. Near the river walk and the Peace Center. Great restaurants nearby. Staff was friendly and helpful. Great room with lots of space. We will definitely stay here again when we are in Greenville!"

Best Western Plus Greenville I-385 Inn & Suites

8/10 Good

"Nice clean place, not fancy but comfortable. The included breakfast would be improved by some non-sugary options. Overall good value for the price."

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

SAR 268

SAR 295 total

1 Nov - 2 Nov

includes taxes & fees

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

SAR 291

SAR 321 total

25 Oct - 26 Oct

includes taxes & fees

9.2/10 Wonderful! (1,590 reviews)

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

SAR 321

SAR 364 total

18 Oct - 19 Oct

includes taxes & fees

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

SAR 396

SAR 439 total

13 Oct - 14 Oct

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

SAR 396

SAR 439 total

1 Nov - 2 Nov

includes taxes & fees

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

SAR 409

SAR 508 total

13 Oct - 14 Oct

includes taxes & fees

Find hotels in Upstate South Carolina, SC from SAR 234

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Best Western Plus Greenville I-385 Inn & Suites

2. Embassy Suites Greenville Golf Resort & Conference Center

3. Drury Inn & Suites Greenville

4. DoubleTree by Hilton Greenville Woodruff Road

5. Hilton Garden Inn Greenville

6. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

7. Tru by Hilton Greenville Woodruff Road

8. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

9. Holiday Inn Greenville - Woodruff Road by IHG

10. SpringHill Suites by Marriott Greenville Downtown

11. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

12. Hyatt Place Greenville Downtown

13. Hampton Inn Greenville I-385 - Woodruff Rd.

14. Homewood Suites by Hilton Greenville Downtown

15. Holiday Inn Express & Suites Greenville - Downtown by IHG

16. Hilton Greenville

17. Courtyard by Marriott Greenville Haywood Mall

18. Courtyard by Marriott Greenville Downtown

19. Comfort Suites Piedmont - Greenville South

20. Courtyard by Marriott Greenville Mauldin

Vacation Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Mint House Greenville Downtown by Kasa

Carolina Camp Cedar

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Clemson Memorabilia House

Carolina Landing RV Resort - Caravan Park

Greer Guest House < 1 Mi to Park & Downtown Area!

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Stay at Jos Taylor Retreat: 9 Mi to Greenville!

Families Welcome, Fenced Yard: Inviting Greer Home

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Cleveland Home w/ South Saluda Fishing Access

8 Mi to Clemson: Peaceful Family Home w/ Yard

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Memorial Stadium

BMW Performance Center

Greenville Convention Center

Haywood Mall

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Hotel Hartness

Hyatt Place Greenville Downtown

Best Western Plus Greenville I-385 Inn & Suites

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star-rating

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