Photo by Visit Greenville, South Carolina

Find hotels in Upstate South Carolina, SC from SAR 249
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Apart hotel
Family friendly
Check prices for these dates
Our top choices for Upstate South Carolina hotels

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (483 reviews)
The price is SAR 300
SAR 327 total
includes taxes & fees
17 May - 18 May

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (788 reviews)
The price is SAR 382
SAR 427 total
includes taxes & fees
17 May - 18 May

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (710 reviews)
The price is SAR 324
SAR 354 total
includes taxes & fees
30 May - 31 May

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,196 reviews)
The price is SAR 445
SAR 490 total
includes taxes & fees
24 May - 25 May

Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.2 out of 10, Very Good, (1,006 reviews)
The price is SAR 316
SAR 350 total
includes taxes & fees
18 May - 19 May

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,005 reviews)
The price is SAR 371
SAR 412 total
includes taxes & fees
11 May - 12 May

Best Western Greenville Airport Inn
Best Western Greenville Airport InnGreenville
7.8 out of 10, Good, (1,013 reviews)
The price is SAR 287
SAR 316 total
includes taxes & fees
13 May - 14 May

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
La Quinta by Wyndham Haywood Mall-Near Greenville DowntownGreenville
7.4 out of 10, Good, (1,128 reviews)
The price is SAR 257
SAR 282 total
includes taxes & fees
17 May - 18 May

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is SAR 252
SAR 277 total
includes taxes & fees
10 May - 11 May

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (547 reviews)
The price is SAR 240
SAR 282 total
includes taxes & fees
5 Jun - 6 Jun

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
8.6 out of 10, Excellent, (918 reviews)
The price is SAR 361
SAR 401 total
includes taxes & fees
24 May - 25 May

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (891 reviews)
The price is SAR 393
SAR 437 total
includes taxes & fees
29 May - 30 May

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (736 reviews)
The price is SAR 428
SAR 479 total
includes taxes & fees
25 May - 26 May

Comfort Suites At WestGate Mall
Comfort Suites At WestGate MallSpartanburg
8.4 out of 10, Very Good, (1,012 reviews)
The price is SAR 336
SAR 381 total
includes taxes & fees
7 Jun - 8 Jun

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,004 reviews)
The price is SAR 409
SAR 508 total
includes taxes & fees
12 May - 13 May

Hilton Garden Inn Anderson
Hilton Garden Inn AndersonAnderson
9.0 out of 10, Wonderful, (721 reviews)
The price is SAR 373
SAR 414 total
includes taxes & fees
25 May - 26 May

Sleep Inn Gaffney at I-85
Sleep Inn Gaffney at I-85Gaffney
7.6 out of 10, Good, (341 reviews)
The price is SAR 268
SAR 300 total
includes taxes & fees
30 May - 31 May

Days Inn by Wyndham Greenville South/Mauldin
Days Inn by Wyndham Greenville South/MauldinMauldin
7.6 out of 10, Good, (692 reviews)
The price is SAR 265
SAR 291 total
includes taxes & fees
17 May - 18 May

Wingate by Wyndham - Greenville-Airport
Wingate by Wyndham - Greenville-AirportGreenville
8.4 out of 10, Very Good, (1,007 reviews)
The price is SAR 301
SAR 331 total
includes taxes & fees
17 May - 18 May

Quality Inn & Suites Greenville - Haywood Mall
Quality Inn & Suites Greenville - Haywood MallGreenville
7.4 out of 10, Good, (1,011 reviews)
The price is SAR 263
SAR 300 total
includes taxes & fees
10 May - 11 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (71 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is SAR 224 per night from Jun 7 to Jun 8
SAR 224
SAR 249 total
7 Jun - 8 Jun
includes taxes & fees
6/10 (599 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
39 properties








































































































































