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19 Aug - 20 Aug
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20 Aug - 21 Aug
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21 Aug - 23 Aug
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Our top choices for Upstate South Carolina hotels

1. Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
Greenville
United States
Nancy
SAR 311
SAR 342 total
includes taxes & fees
30 Aug - 31 Aug
Best Western Plus Greenville I-385 Inn & Suites

2. Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
Greenville
United States
Robert
SAR 366
SAR 415 total
includes taxes & fees
30 Aug - 31 Aug
Embassy Suites Greenville Golf Resort & Conference Center

3. Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
Greenville
United States
Gohan
SAR 432
SAR 475 total
includes taxes & fees
30 Aug - 31 Aug
Drury Inn & Suites Greenville

4. Hilton Greenville

Hilton Greenville
Greenville
United States
Gildardo
SAR 385
SAR 436 total
includes taxes & fees
7 Sep - 8 Sep
Hilton Greenville

5. Courtyard by Marriott Greenville Mauldin

Courtyard by Marriott Greenville Mauldin
Greenville
United States
sarah
SAR 447
SAR 491 total
includes taxes & fees
27 Aug - 28 Aug
Courtyard by Marriott Greenville Mauldin

6. DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
Greenville
United States
JOANNA
SAR 428
SAR 485 total
includes taxes & fees
30 Aug - 31 Aug
DoubleTree by Hilton Greenville Woodruff Road

7. Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hampton Inn & Suites Greenville-Downtown-RiverPlace
Greenville Downtown
United States
Layne
SAR 557
SAR 631 total
includes taxes & fees
3 Sep - 4 Sep
Hampton Inn & Suites Greenville-Downtown-RiverPlace

8. Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall
Greenville
United States
Brittney
SAR 321
SAR 364 total
includes taxes & fees
23 Aug - 24 Aug
Comfort Inn Greenville - Haywood Mall

9. Hilton Garden Inn Greenville

Hilton Garden Inn Greenville
Greenville
United States
Robert
SAR 336
SAR 380 total
includes taxes & fees
13 Sep - 14 Sep
Hilton Garden Inn Greenville

10. Homewood Suites by Hilton Greenville Downtown

Homewood Suites by Hilton Greenville Downtown
Greenville Downtown
United States
Brandon
SAR 520
SAR 590 total
includes taxes & fees
7 Sep - 8 Sep
Homewood Suites by Hilton Greenville Downtown

11. Embassy Suites by Hilton Greenville Downtown Riverplace

Embassy Suites by Hilton Greenville Downtown Riverplace
Greenville Downtown
United States
LATOYA
SAR 551
SAR 624 total
includes taxes & fees
8 Sep - 9 Sep
Embassy Suites by Hilton Greenville Downtown Riverplace

12. SpringHill Suites by Marriott Greenville Downtown

SpringHill Suites by Marriott Greenville Downtown
Greenville Downtown
United States
Douglas
SAR 515
SAR 583 total
includes taxes & fees
31 Aug - 1 Sep
SpringHill Suites by Marriott Greenville Downtown

13. Hampton Inn Greer Greenville, SC

Hampton Inn Greer Greenville, SC
Greer
United States
Teresa
SAR 541
SAR 589 total
includes taxes & fees
22 Aug - 23 Aug
Hampton Inn Greer Greenville, SC

14. Holiday Inn Express & Suites Greenville - Taylors by IHG

Holiday Inn Express & Suites Greenville - Taylors by IHG
Greenville
United States
John
SAR 413
SAR 468 total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express & Suites Greenville - Taylors by IHG

15. Fairfield Inn & Suites by Marriott Greenville Simpsonville

Fairfield Inn & Suites by Marriott Greenville Simpsonville
Simpsonville
United States
Carole
SAR 332
SAR 365 total
includes taxes & fees
31 Aug - 1 Sep
Fairfield Inn & Suites by Marriott Greenville Simpsonville

16. Hyatt Place Greenville Downtown

Hyatt Place Greenville Downtown
Greenville Downtown
United States
Melanie
SAR 491
SAR 557 total
includes taxes & fees
7 Sep - 8 Sep
Hyatt Place Greenville Downtown

17. Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.
Greenville
United States
Anne
SAR 382
SAR 433 total
includes taxes & fees
7 Sep - 8 Sep
Hampton Inn Greenville I-385 - Woodruff Rd.

18. Comfort Suites Greenville Airport

Comfort Suites Greenville Airport
Greenville
United States
Chandler
SAR 370
SAR 419 total
includes taxes & fees
13 Sep - 14 Sep
Comfort Suites Greenville Airport

19. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Greenville
United States
Steven
SAR 287
SAR 316 total
includes taxes & fees
10 Sep - 11 Sep
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

20. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Greenville
United States
Cole
SAR 277
SAR 314 total
includes taxes & fees
7 Sep - 8 Sep
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
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Vacation Rentals in Upstate South Carolina

Aparthotel

stayAPT Suites Greenville-Haywood Mall

stayAPT Suites Greenville-Haywood Mall
Greenville
"All the staff from front desk to housekeeping were excellent, friendly and helpful. If looking for rooms with a feel like home StayApt is what you are looking for. I recommend reserving here great place if you want to cook your own meals"
stayAPT Suites Greenville-Haywood Mall
Apartment

Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
Greenville Downtown
"Love the location. Room was great."
Mint House Greenville Downtown by Kasa
Cottage

Claires Cottage ~ 4 Mi to Downtown Greenville!

Claires Cottage ~ 4 Mi to Downtown Greenville!
Greenville
"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."
Claires Cottage ~ 4 Mi to Downtown Greenville!
Aparthotel

The Station by Compo Hotels

The Station by Compo Hotels
Travelers Rest
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
The Station by Compo Hotels
Aparthotel

Landing Apartments - Lyman

Landing Apartments - Lyman
Lyman
"Great room that was nice and clean. Smooth check-in."
Landing Apartments - Lyman
Mobile Home

Carolina Landing RV Resort - Caravan Park

Carolina Landing RV Resort - Caravan Park
Fair Play
"Very nice stay with friendly staff"
Carolina Landing RV Resort - Caravan Park
Cottage

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Cozy Greenville Bungalow ~ 2 Mi to Downtown!
Greenville
"Amazing place. Great host. "
Cozy Greenville Bungalow ~ 2 Mi to Downtown!
Cottage

Stay at Jos Taylor Retreat: 9 Mi to Greenville!

Stay at Jos Taylor Retreat: 9 Mi to Greenville!
Taylors
"This rental is a time capsule that takes you back to Grandma and Grandpa's home. The owner is great to communicate with, as well as their property manager. Quaint older furniture, complete with blankets on the couches. There's all you need to cook and even a great cast-iron frying pan. I wish we had stayed here longer."
Stay at Jos Taylor Retreat: 9 Mi to Greenville!
Apartment

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Serene Travelers Rest Apartment: 7 Mi to Downtown!
Travelers Rest
"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "
Serene Travelers Rest Apartment: 7 Mi to Downtown!
Cottage

Families Welcome, Fenced Yard: Inviting Greer Home

Families Welcome, Fenced Yard: Inviting Greer Home
Greer
"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."
Families Welcome, Fenced Yard: Inviting Greer Home
Cottage

1 Mi to Downtown Greer: Family Home w/ Gazebo!

1 Mi to Downtown Greer: Family Home w/ Gazebo!
Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
1 Mi to Downtown Greer: Family Home w/ Gazebo!
Cottage

Serene Cabin w/ Pond & Creek on South Saluda River

Serene Cabin w/ Pond & Creek on South Saluda River
Cleveland
"I chose this cabin due to its close proximity to the pretty place chapel. The property was BEAUTIFUL and tucked away. The silence and change of scenery was well needed and felt like we were at home. I honestly don’t have enough good things to say about the host Mr. Steve and his generosity and professionalism!"
Serene Cabin w/ Pond & Creek on South Saluda River
Cottage

9 Mi to Devils Fork State Park: Getaway w/ Porch!

9 Mi to Devils Fork State Park: Getaway w/ Porch!
Tamassee
"Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!"
9 Mi to Devils Fork State Park: Getaway w/ Porch!
Cottage

Rustic Sunset Escape on 67 Acres: Outdoor Kitchen

Rustic Sunset Escape on 67 Acres: Outdoor Kitchen
Sunset
"Wonderful, thank u"
Rustic Sunset Escape on 67 Acres: Outdoor Kitchen
Cottage

Mountain Rest Cottage w/ Gas Fireplace!

Mountain Rest Cottage w/ Gas Fireplace!
Mountain Rest
"Unit is attached to the owners house. The drive way leading up to the apartment is loose gravel. Not safe for a heavy motorcycle. "
Mountain Rest Cottage w/ Gas Fireplace!
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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
See properties
A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
See properties
A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.
Photo by Karyn Thompson

Fred W. Symmes Chapel

9.8/10 (29 reviews)
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
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Greenville Convention Center

8.4/10 (571 reviews)
Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
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Memorial Stadium

9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.
See properties

Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
An aerial view of a park with a winding path, trees in autumn colors, and a bridge.
Photo by Visit Greenville, South Carolina

Top Upstate South Carolina Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"This was a great location. It is a big property and all of the rooms have an inside view of the main lobby and guest area. They had a fun activity to find Reedy the frog placed throughout the property. It was a good scavenger hunt activity for all ages. The rooms were good sized and the suites are always great. There was plenty of easy parking and the breakfast was great. The staff were all nice and we enjoyed our stay"
Sandra 2-night trip
Posted 1 hour ago
Embassy Suites Greenville Golf Resort & Conference Center
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

10/10 Excellent
"Great experience , staff was helpful and friendly"
Chad 2-night trip
Posted 5 hours ago
Hyatt Place Greenville/Haywood
Hilton Greenville

Hilton Greenville

10/10 Excellent
"Great location, staff, condition. Thanks. I’ll be back"
James 1-night trip
Posted 16 hours ago
Hilton Greenville
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent
"This was the most enjoyable stay I’ve had in Clemson! Everything was great. I will stay here again next year!"
James 2-night trip
Posted 23 hours ago
Best Western Plus Clemson Hotel & Conference Center
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"N/a"
Kelly 2-night trip
Posted 23 hours ago
The Shepherd Hotel Downtown Clemson
Inn @ Clemson

Inn @ Clemson

8/10 Good
"Close to campus, staff was amazing, amenities were ehh, breakfast was small, gym was out of service."
Daniela 3-night trip
Posted 2 days ago
Inn @ Clemson
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

10/10 Excellent
"Stayed during Clemson move in and it was great. Very reasonable price, clean room and good breakfast. Also super close to campus!"
Beth 2-night trip
Posted 2 days ago
Comfort Inn & Suites Clemson - University Area
Hotel Hartness

Hotel Hartness

10/10 Excellent
"Amazing!"
Kim 1-night trip
Posted 3 days ago
Hotel Hartness
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

8/10 Good
"Checking in was odd because we booked ahead of time: but still required a card to check in. WiFi password was confusing until we figured out, beds were a little firm for my liking but the pillows were great. Room was clean and housekeeping was nice; parking kinda sucks tho. We didn’t eat the breakfast or use the pool/fitness center. We typically enjoyed our time in the city. But, it’s very centrally located to a lot, most things were only 10 mins away!"
shamar 5-night trip
Posted 3 days ago
Best Western Plus Greenville I-385 Inn & Suites

More cheap stays in Upstate South Carolina

Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

60 Roper Mountain Rd Greenville SC
SAR 227
SAR 249 total
30 Aug - 31 Aug
includes taxes & fees
Days Inn by Wyndham Greenville
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC
SAR 311
SAR 342 total
30 Aug - 31 Aug
includes taxes & fees
9.2/10 Wonderful! (1,562 reviews)
Best Western Plus Greenville I-385 Inn & Suites
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC
SAR 321
SAR 364 total
23 Aug - 24 Aug
includes taxes & fees
Comfort Inn Greenville - Haywood Mall
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Ln Spartanburg SC
SAR 355
SAR 394 total
30 Aug - 31 Aug
includes taxes & fees
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC
SAR 380
SAR 422 total
22 Aug - 23 Aug
includes taxes & fees
8/10 Very Good! (1,035 reviews)
Best Western Plus Clemson Hotel & Conference Center
Lakeside Lodge Clemson

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC
SAR 409
SAR 508 total
20 Aug - 21 Aug
includes taxes & fees
Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star-rating