Find Resorts & Hotels with Spas in Southwest Illinois, IL

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Southwest Illinois Resorts & Hotels with Spas

Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
This weekend
29 Aug - 31 Aug
Next weekend
5 Sep - 7 Sep

Top Southwest Illinois Resorts & Hotels with Spas

Our top choices for Southwest Illinois hotels with a spa

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"The hotel was very nice and the staff were super helpful. I would stay here again!"
The price is SAR 387
SAR 436 total
includes taxes & fees
7 Sep - 8 Sep
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Walker's Bluff Casino Resort
Indoor pool, seasonal outdoor pool

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (366)
"I would love to stay here again, shoutout to their beds!! "
Walker's Bluff Casino Resort
Ameristar Casino Resort and Spa
6 restaurants, breakfast served

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1004)
"Loved my stay here will be back "
The price is SAR 635
SAR 804 total
includes taxes & fees
2 Sep - 3 Sep
Ameristar Casino Resort and Spa
21C Museum Hotel St Louis
Exterior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1334)
"Amazing hotel!"
The price is SAR 539
SAR 649 total
includes taxes & fees
1 Sep - 2 Sep
21C Museum Hotel St Louis
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1004)
"We’ve stayed at this hotel several times and keep coming back. Great hotel staff and property. "
The price is SAR 1,595
SAR 1,865 total
includes taxes & fees
21 Sep - 22 Sep
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (545)
"Great place"
The price is SAR 1,947
SAR 2,269 total
includes taxes & fees
21 Sep - 22 Sep
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Spa hotels with pools in Southwest Illinois

Walker's Bluff Casino Resort
Indoor pool, seasonal outdoor pool

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (366)
Walker's Bluff Casino Resort

Spa hotels with hot tubs in Southwest Illinois

Walker's Bluff Casino Resort
Indoor pool, seasonal outdoor pool

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (366)
Walker's Bluff Casino Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southwest Illinois Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia