Search Vacation Homes in South Carolina Midlands

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
12 Sep - 14 Sep
In one month
26 Sep - 28 Sep
In two months
24 Oct - 26 Oct
In three months
21 Nov - 23 Nov

Vacation Homes in South Carolina Midlands

Quintessential 2-bedroom bungalow in the heart of Shandon in Columbia, SC.
Living area

Quintessential 2-bedroom bungalow in the heart of Shandon in Columbia, SC.

2.0 star property
10.0 out of 10, Exceptional, (30)
"Wonderful area. Quiet street. Space has everything we needed."
Quintessential 2-bedroom bungalow in the heart of Shandon in Columbia, SC.
Family sized comfort near Fort Jackson
Property grounds

Family sized comfort near Fort Jackson

10.0 out of 10, Exceptional, (3)
"Beautiful "
Family sized comfort near Fort Jackson
Cozy 2-bedroom townhome in charming Lexington with WiFi, AC
Fridge, microwave, oven, stovetop

Cozy 2-bedroom townhome in charming Lexington with WiFi, AC

9.2 out of 10, Wonderful, (10)
"Everything was nice and clean. Great location to all activities and restaurants. "
Cozy 2-bedroom townhome in charming Lexington with WiFi, AC
Beautiful & Spacious with Hot Tub, Game Room & More. Large Yard Near the Dam!
Outdoor spa tub

Beautiful & Spacious with Hot Tub, Game Room & More. Large Yard Near the Dam!

9.8 out of 10, Exceptional, (130)
"Great stay, every thing was easy, clean and as advertised! We would stay here again!"
Beautiful & Spacious with Hot Tub, Game Room & More. Large Yard Near the Dam!
Private Dock + Pool Table: Lake Marion Getaway
Dining

Private Dock + Pool Table: Lake Marion Getaway

9.0 out of 10, Wonderful, (2)
"Great property, we will return and highly recommended."
Private Dock + Pool Table: Lake Marion Getaway
Luxury Villa in downtown Columbia with hot tub. Pet friendly!
Exterior

Luxury Villa in downtown Columbia with hot tub. Pet friendly!

9.2 out of 10, Wonderful, (23)
"Convenient location, quiet street, clean, comfortable beds "
The price is SAR 929
SAR 1,599 total
includes taxes & fees
29 Aug - 30 Aug
Luxury Villa in downtown Columbia with hot tub. Pet friendly!
Renovated 2-bedroom farm-style house on Lake Murray. Bring Your Fishing Rod
Property grounds

Renovated 2-bedroom farm-style house on Lake Murray. Bring Your Fishing Rod

9.6 out of 10, Exceptional, (10)
"Beautiful view, great location & comfortable beds. "
Renovated 2-bedroom farm-style house on Lake Murray. Bring Your Fishing Rod
Cozy 3-bedroom Home in West Columbia located only 5 minutes from downtown vista.
Exterior

Cozy 3-bedroom Home in West Columbia located only 5 minutes from downtown vista.

9.0 out of 10, Wonderful, (18)
"House was comfortable and location was good for weekend activities. Baseball game at Founders Park and Zoo less than 15 minute drive. "
The price is SAR 413
SAR 770 total
includes taxes & fees
25 Sep - 26 Sep
Cozy 3-bedroom Home in West Columbia located only 5 minutes from downtown vista.
Cozy Hometown Getaway!
Interior

Cozy Hometown Getaway!

10.0 out of 10, Exceptional, (53)
"Thoroughly enjoyed our stay there. Rented it to visit family and found so much to do. Will definitely book again. Wendy is an awesome host!"
The price is SAR 825
SAR 1,334 total
includes taxes & fees
31 Aug - 1 Sep
Cozy Hometown Getaway!
Luxurious Lakefront retreat with own private dock.
Interior

Luxurious Lakefront retreat with own private dock.

The price is SAR 2,814
SAR 4,154 total
includes taxes & fees
15 Sep - 16 Sep
Luxurious Lakefront retreat with own private dock.
WHITE KNOLL BUNGALOW
Private kitchen

WHITE KNOLL BUNGALOW

2.0 star property
9.0 out of 10, Wonderful, (17)
"Thanks for allowing us too stay !!! "
WHITE KNOLL BUNGALOW
The Cozy Cove - Lake House on Lake Wylie Nc
Property grounds

The Cozy Cove - Lake House on Lake Wylie Nc

10.0 out of 10, Exceptional, (147)
"Great place on the lake with lots of room. House is well equipped with everything you would want. In a nice quiet neighborhood. Had a great time for a much need rest and relaxation with my sister"
The Cozy Cove - Lake House on Lake Wylie Nc
Lake Cottage in Chapin with Private Dock
Fridge, microwave, oven, stovetop

Lake Cottage in Chapin with Private Dock

10.0 out of 10, Exceptional, (13)
"This cozy little house was the perfect place to relax. The house was beautifully decorated and clean with the perfect amount of actuvities to keep everyone busy and happy. The owner even let us extend our stay an hour or so bc we just weren't ready to leave we typically rent a different house every year, but this will always be our first pick now!"
Lake Cottage in Chapin with Private Dock
Luxurious & Newly Renovated 3 BR Bungalow - Minutes from USC - Sleeps 8
Exterior

Luxurious & Newly Renovated 3 BR Bungalow - Minutes from USC - Sleeps 8

The price is SAR 672
SAR 1,581 total
includes taxes & fees
1 Sep - 2 Sep
Luxurious & Newly Renovated 3 BR Bungalow - Minutes from USC - Sleeps 8
Lakeside Oasis: Fort Jackson Family Retreat
Property grounds

Lakeside Oasis: Fort Jackson Family Retreat

9.4 out of 10, Exceptional, (10)
"Beautiful home! Easy experience from start to finish. Property manager was in contact daily to make sure we had everything we needed. Great experience and will definitely stay there again!"
Lakeside Oasis: Fort Jackson Family Retreat
NoMa Green House
Smart TV

NoMa Green House

10.0 out of 10, Exceptional, (60)
"Great property! Excellently maintained and nicely decorated. "
The price is SAR 382
SAR 970 total
includes taxes & fees
1 Sep - 2 Sep
NoMa Green House
Charming 5-bedroom home in Lexington, S.C.
Property grounds

Charming 5-bedroom home in Lexington, S.C.

Charming 5-bedroom home in Lexington, S.C.
Jim & Mary's
Fridge, microwave, oven, stovetop

Jim & Mary's

9.6 out of 10, Exceptional, (71)
"The house was clean and well kept, perfect for our short stay. "
The price is SAR 540
SAR 1,260 total
includes taxes & fees
29 Aug - 30 Aug
Jim & Mary's
5 bedroom spacious home, with charcoal grill and seating. Peaceful neighborhood.
Pool

5 bedroom spacious home, with charcoal grill and seating. Peaceful neighborhood.

8.8 out of 10, Excellent, (15)
"Our stay was perfect. "
The price is SAR 507
SAR 1,021 total
includes taxes & fees
1 Sep - 2 Sep
5 bedroom spacious home, with charcoal grill and seating. Peaceful neighborhood.
New Cozy Stay Columbia and Ft. Jackson
Fridge, microwave, oven, stovetop

New Cozy Stay Columbia and Ft. Jackson

10.0 out of 10, Exceptional, (76)
"Great stay! "
New Cozy Stay Columbia and Ft. Jackson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South Carolina Midlands Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia