Search Vacation Homes in Santee

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
18 Jul - 20 Jul
In two weeks
25 Jul - 27 Jul
In one month
8 Aug - 10 Aug
In two months
5 Sep - 7 Sep

Vacation Homes in Santee

Lake Marion Home: Kayaks, Dock, Waterfront Fun!
Dining

Lake Marion Home: Kayaks, Dock, Waterfront Fun!

9.0 out of 10, Wonderful, (6)
"This property was a very nice getaway for my friend and I. We enjoyed the quite neighborhood and sitting on the back porch enjoying the early fall weather. Hope to stay again in the future. "
Lake Marion Home: Kayaks, Dock, Waterfront Fun!
Courtney House on Lake Marion
Property grounds

Courtney House on Lake Marion

10.0 out of 10, Exceptional, (94)
"My family and I had a great time staying at the Courtney House. Ms Judy and her husband were great hosts. We will definitely be coming back to stay."
Courtney House on Lake Marion
Beautiful lake home to make your family vacation extra special!
Fridge, microwave, oven, stovetop

Beautiful lake home to make your family vacation extra special!

9.0 out of 10, Wonderful, (56)
"This was an awesome stay! Home was clean and comfortable. Great hosts!"
Beautiful lake home to make your family vacation extra special!
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Outdoor dining

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (32)
"We needed a place with two separate bedrooms. This property fit the bill. Perfect for our trip. Nice accommodations. Would definitely recommend this property. "
The price is SAR 549
SAR 1,429 total
includes taxes & fees
22 Jul - 23 Jul
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Property grounds

Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.

10.0 out of 10, Exceptional, (4)
"We had a beautiful stay on the water . The property manager was so nice and informative. We had a small issue and it was taken care of right away. This is a great place to stay. "
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
LAKE MARION LAKE FRONT VACATION RENTAL
Terrace/patio

LAKE MARION LAKE FRONT VACATION RENTAL

9.4 out of 10, Exceptional, (87)
"Very good "
LAKE MARION LAKE FRONT VACATION RENTAL
Lakefront Retreat on Lake Marion
Outdoor dining

Lakefront Retreat on Lake Marion

9.4 out of 10, Exceptional, (30)
"Great stay, wonderful location on the water."
Lakefront Retreat on Lake Marion
Beautiful Cottage between Lake Moultrie and Lake Marion
Smart TV, video games, DVD player, books

Beautiful Cottage between Lake Moultrie and Lake Marion

9.8 out of 10, Exceptional, (136)
"Great visit! Best house on the water in the lake area for our needs! "
Beautiful Cottage between Lake Moultrie and Lake Marion
Sweet Marion - Dock + Boat Ramp + Spa + Lakefront
Fridge, microwave, oven, stovetop

Sweet Marion - Dock + Boat Ramp + Spa + Lakefront

8.8 out of 10, Excellent, (13)
"Very nice "
The price is SAR 900
SAR 1,973 total
includes taxes & fees
9 Aug - 10 Aug
Sweet Marion - Dock + Boat Ramp + Spa + Lakefront
Archie's Lake Daze Cottage
Property grounds

Archie's Lake Daze Cottage

10.0 out of 10, Exceptional, (72)
"Archie’s Lake Daze cottage was everything we expected and more! We will definitely book again."
Archie's Lake Daze Cottage
Wyndham Vacation Resorts Lake Marion
Exterior

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.2 out of 10, Wonderful, (19)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion
Spacious Family Home on Lake Marion w/ Boat Ramp!
Interior

Spacious Family Home on Lake Marion w/ Boat Ramp!

10.0 out of 10, Exceptional, (5)
"Awesome place. Had everything thing we needed. Comfy too."
Spacious Family Home on Lake Marion w/ Boat Ramp!
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Exterior

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

10.0 out of 10, Exceptional, (37)
"Very nice place to stay. We had everything we needed for the comforts of home. "
The price is SAR 608
SAR 1,162 total
includes taxes & fees
17 Jul - 18 Jul
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Lake Marion Lakehouse with 180° lake view
Exterior

Lake Marion Lakehouse with 180° lake view

10.0 out of 10, Exceptional, (63)
"Very nice and clean property. "
Lake Marion Lakehouse with 180° lake view
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Property grounds

New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable

9.8 out of 10, Exceptional, (167)
"This property was great for our needs and I would recommend it to anyone looking for a getaway or event which needs more capacity for guests."
New Listing SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Lake Marion Getaway!
TV

Lake Marion Getaway!

2.0 star property
9.2 out of 10, Wonderful, (38)
"Very nice host. Place was clean and had plenty of room. Family enjoyed their stay. "
Lake Marion Getaway!
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Fridge, microwave, oven, stovetop

6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates

6.8 out of 10, (9)
"Wonderful place to stay with a group. Rustic but has everything you need. Very comfortable. "
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion
Interior

Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion

2.0 star property
9.0 out of 10, Wonderful, (2)
"We really enjoyed staying here. There was plenty of space for parking cars/boats. The house was clean and spacious and had everything that we needed. The host was responsive when we had questions. Everyone that we met was very nice. We would definitely stay here again. "
Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion
Lake Marion in South Carolina.
Property grounds

Lake Marion in South Carolina.

7.8 out of 10, Good, (9)
"Really enjoyed , good , nice place and good communication also was very clean"
Lake Marion in South Carolina.
Private Dock + Pool Table: Lake Marion Getaway
Dining

Private Dock + Pool Table: Lake Marion Getaway

9.0 out of 10, Wonderful, (2)
"Great property, we will return and highly recommended."
Private Dock + Pool Table: Lake Marion Getaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free