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Compare 76 Vacation Homes in Sikeston with updated reviews, rates, and availability.

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (131)
"Great place."
The price is SAR 563
SAR 907 total
includes taxes & fees
11 May - 12 May
Serenity South -- Gardens, River-Views, and Refreshing Space

Notting Hill Cottage

9.6 out of 10, Exceptional, (311)
"Got away with wife and kids (10 and 8). Perfect stay!"
Notting Hill Cottage

Beautiful location in the secluded woods

9.8 out of 10, Exceptional, (26)
"This property is wonderful for BBQs and having family in town. "
The price is SAR 431
SAR 698 total
includes taxes & fees
6 May - 7 May
Beautiful location in the secluded woods

* On the Wine Trail * Hot Tub * Wi-Fi *

9.8 out of 10, Exceptional, (227)
"Thank you for your hospitality and quick assistance to any need. The apartment was cozy, clean and comfortable. We enjoy very much our stay and would love to be back for sure."
* On the Wine Trail * Hot Tub * Wi-Fi *

Wine Trail, Cozy Cabin plus hot tub

9.8 out of 10, Exceptional, (94)
"Loved our weekend away at this little gem! It was so quiet and the hot tub was so relaxing! We definitely plan on returning."
Wine Trail, Cozy Cabin plus hot tub

* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

10.0 out of 10, Exceptional, (93)
"Centrally located to all the wineries. "
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural

10.0 out of 10, Exceptional, (115)
"We enjoyed our stay! House was perfect for us, location was great for the planned visits. Great communication from host along with a nice welcome basket on the table. Looking forward to our return trip in April!!"
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural

Brick Estate with pool in Quiet Carbondale Neighborhood

9.4 out of 10, Exceptional, (85)
"We enjoyed our stay here very much. The home is large yet cozy and located in a lovely quiet neighborhood. Perfect for visiting local family and friends!"
Brick Estate with pool in Quiet Carbondale Neighborhood

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.6 out of 10, Excellent, (29)
"Not bad but Hot tub was not accessible and the hotwater in the 2nd bedroom had no hot water."
The price is SAR 746
SAR 1,089 total
includes taxes & fees
6 May - 7 May
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9.4 out of 10, Exceptional, (3)
"Great property would recommend 100%. We did not have to leave the house it had everything we needed for nine adult women to have a great streetlight"
The price is SAR 1,406
SAR 2,117 total
includes taxes & fees
5 Jun - 6 Jun
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Dexter Homestead. Very Cozy & NEW Remodel !

8.0 out of 10, Very Good, (23)
"Plenty of room to move about. Quiet neighborhood. Host took care of all our needs."
The price is SAR 371
SAR 762 total
includes taxes & fees
6 May - 7 May
Dexter Homestead. Very Cozy & NEW Remodel !

Private lake, beach & hot tub, romantic getaway or family vaca

10.0 out of 10, Exceptional, (23)
"Love the peace. "
Private lake, beach & hot tub, romantic getaway or family vaca

'The Lakehouse' Lovely Wappapello Country Home!

9.8 out of 10, Exceptional, (16)
"Home was as describe and we enjoyed a memorable stay."
'The Lakehouse' Lovely Wappapello Country Home!

Charming 2-bedroom house in delightful Jackson with AC, WiFi

10.0 out of 10, Exceptional, (4)
"Nice clean property second stay."
Charming 2-bedroom house in delightful Jackson with AC, WiFi

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

10.0 out of 10, Exceptional, (5)
"A large and comfortable house with cool historical details and just about everything you need to have a great, easy, smooth-running vacation. Great location for downtown exploring."
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

Quaint, Beautiful Home next to SEMO and Hospital

9.8 out of 10, Exceptional, (34)
"Great stay, great location! "
Quaint, Beautiful Home next to SEMO and Hospital

Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

2.0 star property
10.0 out of 10, Exceptional, (10)
"Was a great property for our duck hunting trip to the area for four adults and four children. Great communication and friendly hosts! We love the place and we’ll be back for any future trips. Outside gazebo is fantastic as well."
The price is SAR 750
SAR 919 total
includes taxes & fees
7 May - 8 May
Welcome campers, hikers, fishermen, girls' weekend wine getaways!!

"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau

10.0 out of 10, Exceptional, (14)
"Chip, thanks for our stay in your beautiful house. We had a wonderful Christmas visit thanks to you."
"Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau

Embers of Murphysboro - 5 Star Cabin Sleeps up to 12 - GREAT AMMENITIES!

10.0 out of 10, Exceptional, (10)
"This was our 2nd time enjoying this home. We got to enjoy the pool this time. It was lovely! If you are looking for an expertly equipped, perfectly arranged, exquisitely comfortable home…THIS IS IT!"
Embers of Murphysboro - 5 Star Cabin Sleeps up to 12 - GREAT AMMENITIES!

StarView Vineyards Winery Retreat

10.0 out of 10, Exceptional, (33)
"The house was clean and nicely updated. There was plenty of room for us. The area is easily accessible to activities. "
StarView Vineyards Winery Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Sikeston

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

10.0 out of 10, Exceptional, (126)
"This was our second time staying here & I cannot recommend it enough! The cabin is very well kept & clean. We will definitely be back again! "
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

Beautiful location in the secluded woods

9.8 out of 10, Exceptional, (26)
"This property is wonderful for BBQs and having family in town. "
The price is SAR 431
SAR 698 total
includes taxes & fees
6 May - 7 May
Beautiful location in the secluded woods

Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!

10.0 out of 10, Exceptional, (37)
"Very enjoyable stay"
The price is SAR 818
SAR 1,016 total
includes taxes & fees
12 May - 13 May
Hot Tub - Minutes from Winetrail, SIU, Giant City, Cedar Lake, Shawnee Forest!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.