Photo by Cindy Keese

Find Business Hotels in Seneca, SC

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Seneca Business Hotels

Top Seneca Business Hotels

Our top choices for Seneca business-friendly hotels

Best Western Seneca-Clemson
Lobby

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (601)
"We liked the location. It was easy to explore Lake Keowee from here. The blackout window shades were nice too! The room was so humid that it even made the sheets feel damp. "
The price is SAR 380
SAR 418 total
includes taxes & fees
14 Sep - 15 Sep
Best Western Seneca-Clemson
Hampton Inn & Suites Seneca-Clemson Area
Exterior

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (628)
"The staff were very friendly and helpful. The room was clean and the breakfast was great!"
The price is SAR 473
SAR 520 total
includes taxes & fees
28 Aug - 29 Aug
Hampton Inn & Suites Seneca-Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
Room, 1 King Bed, Non Smoking | Desk, free cribs/infant beds, rollaway beds, free WiFi

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (693)
"The property was near the area that I needed to be in. It has ample shops and restaurants in the area "
The price is SAR 262
SAR 288 total
includes taxes & fees
24 Aug - 25 Aug
Days Inn by Wyndham Seneca / Clemson Area
Quality Inn Seneca Clemson Area US-123
Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very Good, (632)
"Ok hotel for a quick stay "
The price is SAR 301
SAR 368 total
includes taxes & fees
31 Aug - 1 Sep
Quality Inn Seneca Clemson Area US-123
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Seneca Hotel Reviews

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

10/10 Excellent
"Nice clean, comfortable stay with a great breakfast."
karen 1-night trip
Posted 2 days ago
Quality Inn Seneca Clemson Area US-123