The Best Hotels Closest to Santo Spirito Hospital in Rome for 2026

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Our top choices for Santo Spirito Hospital hotels

Panoramic Suite, Terrace | Minibar, in-room safe, desk, laptop workspace

Family Apartment | Minibar, in-room safe, desk, laptop workspace

1. Passpartout Boutique Palace

0.4 km from Santo Spirito Hospital

Mauricio

SAR 1,013

SAR 1,174 total

includes taxes & fees

30 Sep - 1 Oct

Premium bedding, minibar, in-room safe, desk

2. Eccelso Hotel

Prati, 0.8 km from Santo Spirito Hospital

Raydel

SAR 643

SAR 758 total

includes taxes & fees

26 Oct - 27 Oct

Comfort Double Room | Premium bedding, desk, iron/ironing board (on request), WiFi (free)

22-inch TV with digital channels, printers

3. All’Orologio

Ponte, 0.4 km from Santo Spirito Hospital

Michael

SAR 770

SAR 890 total

includes taxes & fees

28 Oct - 29 Oct

Executive Apartment | Premium bedding, in-room safe, WiFi (free), bed sheets

Deluxe Apartment | Living area | 48-inch flat-screen TV with digital channels, TV

4. Be Mate Castel Sant'Angelo

Ponte, 0.4 km from Santo Spirito Hospital

Christopher

SAR 1,756

SAR 1,983 total

includes taxes & fees

5 Oct - 6 Oct

Superior Apartment | 1 bedroom, in-room safe, desk, laptop workspace

5. Now Apartments

Ponte, 0.6 km from Santo Spirito Hospital

Hyejeong

SAR 836

SAR 971 total

includes taxes & fees

28 Sep - 29 Sep

42-inch flat-screen TV with digital channels, TV

6. Charme 308

Ponte, 0.3 km from Santo Spirito Hospital

Mandy

SAR 880

SAR 1,028 total

includes taxes & fees

25 Oct - 26 Oct

Deluxe Room | Minibar, in-room safe, desk, WiFi (free)

Navona Suite | Minibar, in-room safe, desk, WiFi (free)

Presidential Suite, Terrace | Terrace/patio

7. Palazzo Gambirasi Luxury Suite Roma

Ponte, 0.7 km from Santo Spirito Hospital

Michael

SAR 981

SAR 1,139 total

includes taxes & fees

4 Oct - 5 Oct

1 bedroom, premium bedding, memory foam beds, minibar

Superior Room | Bathroom | Shower, hair dryer, bidet, towels

8. Velantia Vaticano - Guesthouse

Prati, 0.6 km from Santo Spirito Hospital

Claudette

SAR 953

SAR 1,108 total

includes taxes & fees

23 Oct - 24 Oct

Junior Suite | In-room safe, desk, blackout drapes, iron/ironing board (on request)

Exclusive Condo | Private kitchen | Electric kettle

9. Passepartout

Parione, 0.6 km from Santo Spirito Hospital

Richard

SAR 959

SAR 1,098 total

includes taxes & fees

25 Oct - 26 Oct

Prestige with Private Garden - Vertical Garden Area | Living area | 42-inch Smart TV with satellite channels, TV

Prestige with Private Garden - Vertical Garden Area | Deep soaking bathtub

10. Horti 14 Borgo Trastevere Hotel

0.7 km from Santo Spirito Hospital

Erin

SAR 932

SAR 1,090 total

includes taxes & fees

28 Sep - 29 Sep

Deluxe Double Room, Jetted Tub, Ground Floor | Jetted tub

11. Navona Street Hotel

Ponte, 0.4 km from Santo Spirito Hospital

Jose A

SAR 1,059

SAR 1,216 total

includes taxes & fees

25 Oct - 26 Oct

Family Apartment | In-room safe, desk, WiFi (free), bed sheets

Family Apartment | Private kitchen | Dining table

12. Be Mate Piazza Navona

Parione, 0.6 km from Santo Spirito Hospital

Inna

SAR 1,312

SAR 1,495 total

includes taxes & fees

29 Sep - 30 Sep

Suite, Jetted Tub (Breakfast at Navona Street Hotel) | Minibar, in-room safe, desk, laptop workspace

13. B&B Rome River Inn

Ponte, 0.4 km from Santo Spirito Hospital

Marny

SAR 855

SAR 991 total

includes taxes & fees

28 Oct - 29 Oct

Luxury Suite | Minibar, in-room safe, desk, blackout drapes

14. Boutique Hotel Piedra Rome City Centre

Prati, 0.5 km from Santo Spirito Hospital

Daisy Ellen Margaret

SAR 814

SAR 946 total

includes taxes & fees

30 Sep - 1 Oct

15. Residenza Adriana

Prati, 0.6 km from Santo Spirito Hospital

hunter

SAR 559

SAR 666 total

includes taxes & fees

26 Oct - 27 Oct

Luxury Apartment, 2 Bedrooms | Premium bedding, in-room safe, iron/ironing board, WiFi (free)

16. HiSuiteROME

Ponte, 0.6 km from Santo Spirito Hospital

Rosemary

SAR 1,393

SAR 1,584 total

includes taxes & fees

5 Oct - 6 Oct

17. Hotel della Conciliazione

0.4 km from Santo Spirito Hospital

Trevor

SAR 983

SAR 1,146 total

includes taxes & fees

26 Oct - 27 Oct

Superior Room | Minibar, in-room safe, desk, laptop workspace

18. Bloom Hotel Rome

0.7 km from Santo Spirito Hospital

Reginold

SAR 713

SAR 835 total

includes taxes & fees

26 Oct - 27 Oct

Superior Double Room | In-room safe, desk, laptop workspace, iron/ironing board (on request)

19. Whim Collection Vaticano Prati

Prati, 0.7 km from Santo Spirito Hospital

"Diletta was incredibly accommodating and helpful! The use of the common room was greatly appreciated! I loved how hands off everything was but still felt able to quickly connect if need be. Plenty of delicious spots around and felt it close to the activities we had planned, we made use of Lime scooters for anything farther but Whim also offers Vespa rentals themselves! Absolutely loved our stay, would book again if ever in Rome!"

Ashley

SAR 640

SAR 764 total

includes taxes & fees

11 Oct - 12 Oct

Premium bedding, down comforters, memory foam beds, minibar

20. The Bridge Suites

Ponte, 0.3 km from Santo Spirito Hospital

Alan and Karen

SAR 689

SAR 809 total

includes taxes & fees

26 Oct - 27 Oct

View all properties

Top Santo Spirito Hospital Hotel Reviews

Passepartout

10/10 Excellent

"The property was well maintained and the team members we dealt with were all helpful. The location was great for our purposes. We were in the middle of the Vatican and most of the historical sites. This is a guesthouse, not traditional hotel. So it wasn’t fancy, as much as it was practical. It’s also in a great neighborhood. We really enjoyed our time in Rome and Having Passepartout as our home base made our time there very enjoyable."

Hotel della Conciliazione

10/10 Excellent

"Breakfast was great. The rooms were clean, comfy and roomy. The staff were always there to help when needed and the location was amazing. Walking distance to so many sites. Restaurants and stores right outside the hotel. Air conditioning worked great and they have an elevator!!"

Vatican Style

10/10 Excellent

"Nice rooms. Service was excellent- we had to leave at 6:15am for the flight and they accommodated us to provide breakfast at 5:45. Great value compared to the other hotel we stayed at center of Rome."

Argentina Residenza Style Hotel

10/10 Excellent

"The position is superb, close to all amenities. The room was spacious and comfortable. Cleanliness was 110%. Check in was easy and the staff were extremely helpful and friendly. We would recommend this hotel."

Hotel Abruzzi

10/10 Excellent

"Was center of it all"

Hotel Nazionale

10/10 Excellent

"Les employés très aidants, souriants. L hôtel est très bien situé pour aller a pied partout."

Starhotels Michelangelo

10/10 Excellent

"Air conditioning is not working great when we were there sept 13 to sept 19 even though we have called front desk and complaint about ac they will adjust or turn on in their hotel system but still not cold we ended up opening the window."

La Residenza dell'Angelo

10/10 Excellent

"Excellent water pressure. The bed was comfortable. The suite was not in the same building as the reception"

Condotti Boutique Hotel

10/10 Excellent

"Great property, convenient apartment, lovely, helpful staff."

Frequently asked questions

What's the area like around Santo Spirito Hospital?

Santo Spirito Hospital is located in a historic area of Rome known for its stunning cathedral and notable monuments. If you're looking for a convenient place to stay, check out the 1968 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Santo Spirito Hospital?

Adjacent to Santo Spirito Hospital, Villa Agrippina Gran Meliá - The Leading Hotels of the World is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good options close by include Hotel Abruzzi and Vatican Style.

How many hotels will I be able to find close to Santo Spirito Hospital?

Expedia has 1968 hotels and other accommodations within a mile from Santo Spirito Hospital.

If I need to cancel the hotel reservation for my stay near Santo Spirito Hospital, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to get top deals close to Santo Spirito Hospital.

Where can I learn more about changing or cancelling my trip in the area near Santo Spirito Hospital?

For more information about changing or cancelling your stay near Santo Spirito Hospital, head over to our customer service page.

What can I see and do near Santo Spirito Hospital?

You might want to spend some time browsing the exhibits at Vatican Museums, Castel Sant'Angelo, or Cloister of Bramante. Piazza Navona, Pantheon, and Trevi Fountain are well-known local landmarks worth a visit. You can check out the local talent at Auditorium Conciliazione, Paul VI Audience Hall, and Sistina Theater.

How can I get to Santo Spirito Hospital?

With so many choices for transportation, seeing all of the area near Santo Spirito Hospital is simple. You can access metro transit at Venezia Tram Stop, Arenula-Cairoli Tram Station, and Barberini Station. If you'd like to explore more of the area, hop aboard a train from Rome Piazzale Flaminio Station, Rome Termini Station, or Rome (XRJ-Termini Rail Station).

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Check prices for these dates

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Our top choices for Santo Spirito Hospital hotels

1. Passpartout Boutique Palace

2. Eccelso Hotel

3. All’Orologio

4. Be Mate Castel Sant'Angelo

5. Now Apartments

6. Charme 308

7. Palazzo Gambirasi Luxury Suite Roma

8. Velantia Vaticano - Guesthouse

9. Passepartout

10. Horti 14 Borgo Trastevere Hotel

11. Navona Street Hotel

12. Be Mate Piazza Navona

13. B&B Rome River Inn

14. Boutique Hotel Piedra Rome City Centre

15. Residenza Adriana

16. HiSuiteROME

17. Hotel della Conciliazione

18. Bloom Hotel Rome

19. Whim Collection Vaticano Prati

20. The Bridge Suites

Top Santo Spirito Hospital Hotel Reviews

Passepartout

Hotel della Conciliazione

Vatican Style

Argentina Residenza Style Hotel

Hotel Abruzzi

Hotel Nazionale

Starhotels Michelangelo

La Residenza dell'Angelo

Condotti Boutique Hotel

Frequently asked questions

Find hotels near Santo Spirito Hospital, Rome from SAR 666

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santo Spirito Hospital hotels

1. Passpartout Boutique Palace

2. Eccelso Hotel

3. All’Orologio

4. Be Mate Castel Sant'Angelo

5. Now Apartments

6. Charme 308

7. Palazzo Gambirasi Luxury Suite Roma

8. Velantia Vaticano - Guesthouse

9. Passepartout

10. Horti 14 Borgo Trastevere Hotel

11. Navona Street Hotel

12. Be Mate Piazza Navona

13. B&B Rome River Inn

14. Boutique Hotel Piedra Rome City Centre

15. Residenza Adriana

16. HiSuiteROME

17. Hotel della Conciliazione

18. Bloom Hotel Rome

19. Whim Collection Vaticano Prati

20. The Bridge Suites

Top Santo Spirito Hospital Hotel Reviews

Passepartout

Hotel della Conciliazione

Vatican Style

Argentina Residenza Style Hotel

Hotel Abruzzi

Hotel Nazionale

Starhotels Michelangelo

La Residenza dell'Angelo

Condotti Boutique Hotel

Frequently asked questions