The Best Hotels Closest to Roswell Park Cancer Institute in Buffalo for 2026

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Our top choices for Roswell Park Cancer Institute hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A grand room with a chandelier, a fireplace, and ornate furniture.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

1. InnBuffalo off Elmwood

Elmwood Village, 2.5 km from Roswell Park Cancer Institute

Terese

SAR 479

SAR 550 total

includes taxes & fees

9 Nov - 10 Nov

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

2. Buffalo Harmony House

Allentown, 1.2 km from Roswell Park Cancer Institute

John

SAR 1,222

SAR 1,421 total

includes taxes & fees

22 Oct - 23 Oct

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

3. The Edward Hotel

Elmwood Village, 2.3 km from Roswell Park Cancer Institute

Grace

SAR 431

SAR 593 total

includes taxes & fees

26 Oct - 27 Oct

A two-story building with a white exterior, a red door, and large windows.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

A hot tub with a wooden fence and a brick building in the background.

4. Buffalo Guesthouse

Allentown, 0.5 km from Roswell Park Cancer Institute

Jan

SAR 581

SAR 667 total

includes taxes & fees

23 Oct - 24 Oct

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

5. The Mansion On Delaware Ave

Allentown, 0.8 km from Roswell Park Cancer Institute

Marilyn

SAR 739

SAR 848 total

includes taxes & fees

25 Oct - 26 Oct

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A modern bar area with a curved counter, leather bar stools, and a large chandelier.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

6. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

John

SAR 985

SAR 1,150 total

includes taxes & fees

19 Nov - 20 Nov

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A spacious bedroom with a large bed, a comfortable armchair, and a view of a body of water through floor-to-ceiling windows.

A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

A modern kitchen with a central island, bar stools, and built-in appliances.

7. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute

James

SAR 942

SAR 1,100 total

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

8. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute

Sara

SAR 591

SAR 690 total

includes taxes & fees

25 Oct - 26 Oct

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

A modern lobby with a seating area, a fireplace, and a large window offering a view of the city.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

9. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute

Diana

SAR 762

SAR 890 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

A modern gym with cardio machines, a mirrored wall, and a blue accent wall.

10. Best Western on the Avenue

Allentown, 0.7 km from Roswell Park Cancer Institute

Alyson

SAR 571

SAR 666 total

includes taxes & fees

16 Nov - 17 Nov

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

A modern living room with a fireplace, comfortable seating, and a herringbone-patterned wall.

A hotel room with a sofa, a desk, a chair, a television, and a large mirror.

An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.

11. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Gerald D

SAR 635

SAR 741 total

includes taxes & fees

15 Nov - 16 Nov

A reception desk with a computer, printer, and keyboard.

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

12. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 1.1 km from Roswell Park Cancer Institute

Sarah

SAR 443

SAR 517 total

includes taxes & fees

16 Nov - 17 Nov

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

A hotel room with a bed, a desk, a chair, and a view of a cityscape through large windows.

A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.

The exterior of the Hilton Garden Inn, featuring a prominent entrance with a large sign, a flag, and a well-maintained sidewalk.

13. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute

Mercedes

SAR 587

SAR 698 total

includes taxes & fees

18 Nov - 19 Nov

A lobby with a staircase, seating area, and a view of the outdoors.

A bathroom with a toilet, sink, and shower curtain.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

A hotel with a classic brick facade, a glass entrance, and flags.

14. Lenox Hotel and Suites

Allentown, 0.8 km from Roswell Park Cancer Institute

Thomas

SAR 393

SAR 450 total

includes taxes & fees

28 Oct - 29 Oct

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

The facade of Hotel at the Lafayette with a classic architectural style, large windows, and a prominent entrance.

A spacious indoor area with wooden flooring, multiple tables and chairs, a central bar area, and large windows allowing natural light.

A spacious lobby with a central seating area, large columns, and a chandelier.

15. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute

Thomas

SAR 568

SAR 663 total

includes taxes & fees

16 Nov - 17 Nov

A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

A conference room with two chairs and a table, large windows with a city view, and a patterned carpet.

A modern hotel room with a dining area, a large bed, and a view of the city.

A modern bar area with seating, a counter with bottles, and a large window.

16. Embassy Suites Buffalo

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Douglas

SAR 666

SAR 778 total

includes taxes & fees

15 Nov - 16 Nov

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.

A Starbucks coffee shop with a modern design, featuring wooden furniture and a spacious layout.

17. Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Joseph

SAR 604

SAR 706 total

includes taxes & fees

25 Oct - 26 Oct

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A bar area with a circular bar counter, multiple hanging light fixtures, and bar stools.

A modern living room with a large window, a flat-screen TV, a sofa, a coffee table, and a patterned rug.

A modern cafe with round tables and chairs, a bar area, and a neon sign.

18. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 0.8 km from Roswell Park Cancer Institute

Anthony T

SAR 747

SAR 872 total

includes taxes & fees

15 Nov - 16 Nov

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A kitchen with wooden cabinets, stainless steel appliances, and a red toaster.

A kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

19. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.6 km from Roswell Park Cancer Institute

SAR 1,114

SAR 1,973 total

includes taxes & fees

22 Oct - 23 Oct

A buffet setup with various food items and utensils.

A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

20. Salvatores Grand Hotel

15.2 km from Roswell Park Cancer Institute

Mary

SAR 634

SAR 721 total

includes taxes & fees

22 Oct - 23 Oct

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Compare popular hotels close to Roswell Park Cancer Institute

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 225 reviews	View
Buffalo Harmony House	10.0 Exceptional 56 reviews	View
The Edward Hotel	9.6 Exceptional 268 reviews	View
Buffalo Guesthouse	9.4 Exceptional 224 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,002 reviews	View

Top Roswell Park Cancer Institute Hotel Reviews

Best Western on the Avenue

10/10 Excellent

"Great place to stay."

Curtiss Hotel, an Ascend Collection Hotel

10/10 Excellent

"The room was very nice. Breakfast was good and the two bars were nice. We really enjoyed the bathroom. The shower jets are really cool. Very convenient for a wing pilgrimage."

Buffalo Guesthouse

8/10 Good

"My room was incredibly dusty and smelled of cigarettes.. owner was very nice,, place had some great architecture but the room was just not cleaned for a guest stay"

The Mansion On Delaware Ave

10/10 Excellent

"Great space Friendly staff"

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10/10 Excellent

"Great"

Patio Perfection in Allentown

10/10 Excellent

"Very close to restaurants and night life. Quick drive into downtown; very convenient. Very clean and comfortable stay! Highly recommend"

Cozy & Modern Victorian in Historic Allentown, Buffalo

10/10 Excellent

"Brandon's home was the absolute perfect location for a long weekend in Buffalo. We were able to walk just steps to one of our favorite restaurants (Gabriel's Gate), and all the bars and markets on Allen Street/Elmwood Ave.. The house had everything we needed and was decorated/furnished so nicely. The beds were super comfy, I slept like baby. The backyard garden was an oasis and I worked for two days from the table in the backyard, wifi was great! The neighbor was very nice too, which is par for the course in Buffalo. Love this city!! Go Bills."

Charming 1BR in Prime Location

10/10 Excellent

"Great host and good people"

MODERN SPACIOUS 2-BR BEST LOCATION IN ALLENTOWN

10/10 Excellent

"Great location. Clean. Near all of the bars and restaurants. Very cozy upstairs living room for watching games etc."

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)

You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.

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Studio Arena Theater

Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's great live music and entertainment choices.

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Shea's 710 Theatre

You can enjoy a show at Shea's 710 Theatre during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Town Ballroom

You can make plans for a show at Town Ballroom during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Trinity Episcopal Church

You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the great live music or attend a sporting event in this family-friendly area.

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Alleyway Theatre

You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the acclaimed theater scene and great live music in this family-friendly area.

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The 9th Ward

You can make plans for a show at The 9th Ward during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Asbury Hall at Babeville

You can make plans for a show at Asbury Hall at Babeville during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Frequently asked questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 71 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

Where can I learn more about changing or cancelling my trip in the area near Roswell Park Cancer Institute?

For more details about changing or cancelling your stay near Roswell Park Cancer Institute, click here.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Find hotels near Roswell Park Cancer Institute, Buffalo from SAR 450

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Treat yourself

Be picky

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Our top choices for Roswell Park Cancer Institute hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. Buffalo Guesthouse

5. The Mansion On Delaware Ave

6. Curtiss Hotel, an Ascend Collection Hotel

7. Buffalo Marriott at LECOM HARBORCENTER

8. Wyndham Garden Buffalo Downtown

9. Courtyard Buffalo Downtown / Canalside

10. Best Western on the Avenue

11. Hampton Inn & Suites Buffalo Downtown

12. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

13. Hilton Garden Inn Buffalo Downtown

14. Lenox Hotel and Suites

15. Hotel at the Lafayette Trademark Collection by Wyndham

16. Embassy Suites Buffalo

17. Hyatt Regency Buffalo / Hotel and Conference Center

18. Aloft by Marriott Buffalo Downtown

19. 4 Mi to Dtwn: Family Home in Buffalo

20. Salvatores Grand Hotel

Compare popular hotels close to Roswell Park Cancer Institute

Top Roswell Park Cancer Institute Hotel Reviews

Best Western on the Avenue

Curtiss Hotel, an Ascend Collection Hotel

Buffalo Guesthouse

The Mansion On Delaware Ave

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Patio Perfection in Allentown

Cozy & Modern Victorian in Historic Allentown, Buffalo

Charming 1BR in Prime Location

MODERN SPACIOUS 2-BR BEST LOCATION IN ALLENTOWN

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

Studio Arena Theater

Shea's 710 Theatre

Town Ballroom

Trinity Episcopal Church

Alleyway Theatre

The 9th Ward

Asbury Hall at Babeville

Frequently asked questions