The Best Hotels Closest to Roswell Park Cancer Institute in Buffalo for 2026

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Our top choices for Roswell Park Cancer Institute hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A grand room with a chandelier, a fireplace, and ornate furniture.

A large, two-story building with a prominent entrance, multiple windows, and a well-maintained garden.

1. InnBuffalo off Elmwood

Elmwood Village, 2.5 km from Roswell Park Cancer Institute

Terese

SAR 509

SAR 584 total

includes taxes & fees

9 Nov - 10 Nov

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

2. Buffalo Harmony House

Allentown, 1.2 km from Roswell Park Cancer Institute

John

SAR 1,223

SAR 1,423 total

includes taxes & fees

14 Oct - 15 Oct

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

3. The Edward Hotel

Elmwood Village, 2.3 km from Roswell Park Cancer Institute

Grace

SAR 426

SAR 587 total

includes taxes & fees

19 Oct - 20 Oct

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

A pool table in a room with patterned carpet, a dining table with chairs, and a red sofa.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

4. The Mansion On Delaware Ave

Allentown, 0.8 km from Roswell Park Cancer Institute

Marilyn

SAR 740

SAR 850 total

includes taxes & fees

18 Oct - 19 Oct

A two-story building with a white exterior, a red door, and large windows.

A hot tub with a wooden fence and a brick building in the background.

A living room with a fireplace, a chandelier, leather sofas, and a glass coffee table.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

5. Buffalo Guesthouse

Allentown, 0.5 km from Roswell Park Cancer Institute

Jan

SAR 562

SAR 645 total

includes taxes & fees

17 Oct - 18 Oct

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

A modern bar area with a curved counter, leather bar stools, and a large chandelier.

6. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

John

SAR 987

SAR 1,152 total

includes taxes & fees

11 Nov - 12 Nov

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A spacious bedroom with a large bed, a comfortable armchair, and a view of a body of water through floor-to-ceiling windows.

A modern kitchen with a central island, bar stools, and built-in appliances.

A modern hotel lobby with a reception desk, seating area, and a large window offering a view of the city.

7. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute

James

SAR 973

SAR 1,136 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

8. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute

Julian

SAR 592

SAR 691 total

includes taxes & fees

26 Oct - 27 Oct

A modern hotel lobby with a bar area, seating, and a large TV screen.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a glass-enclosed area.

A modern restaurant with a long counter, bar stools, and a refrigerated display.

A modern building with a Starbucks on the ground floor, featuring large windows and a flat roof.

9. Residence Inn by Marriott Buffalo Downtown

Allentown, 0.7 km from Roswell Park Cancer Institute

Karen

SAR 891

SAR 1,040 total

includes taxes & fees

8 Nov - 9 Nov

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern lobby with a seating area, a fireplace, and a large window offering a view of the city.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

10. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute

Diana

SAR 763

SAR 891 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

A modern kitchen with a central island, bar stools, and various appliances.

11. Best Western on the Avenue

Allentown, 0.7 km from Roswell Park Cancer Institute

John

SAR 571

SAR 667 total

includes taxes & fees

19 Oct - 20 Oct

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.

A modern living room with a fireplace, comfortable seating, and a herringbone-patterned wall.

A hotel room with a sofa, a desk, a chair, a television, and a large mirror.

12. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Gerald D

SAR 635

SAR 742 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.

A hotel room with a bed, a desk, a chair, and a view of a cityscape through large windows.

The exterior of the Hilton Garden Inn, featuring a prominent entrance with a large sign, a flag, and a well-maintained sidewalk.

13. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute

Mercedes

SAR 587

SAR 686 total

includes taxes & fees

25 Oct - 26 Oct

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

The facade of Hotel at the Lafayette with a classic architectural style, large windows, and a prominent entrance.

A spacious indoor area with wooden flooring, multiple tables and chairs, a central bar area, and large windows allowing natural light.

A modern hotel room with a fireplace, a flat-screen TV, a sofa, and a bed.

14. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute

Angela

SAR 575

SAR 671 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

A gym with exercise equipment, a mirror, and a television.

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 1.1 km from Roswell Park Cancer Institute

SAR 578

SAR 675 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

A modern hotel room with a dining area, a large bed, and a view of the city.

A modern bar area with seating, a counter with bottles, and a large window.

A hotel room with a large bed, a TV mounted on the wall, a city view through the window, and a wooden shelf.

16. Embassy Suites Buffalo

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Michelle

SAR 667

SAR 779 total

includes taxes & fees

25 Oct - 26 Oct

A lobby with a staircase, seating area, and a view of the outdoors.

A hotel room with two beds, a desk, a television, and a window.

A hotel with a classic brick facade, a glass entrance, and flags.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

17. Lenox Hotel and Suites

Allentown, 0.8 km from Roswell Park Cancer Institute

Thomas

SAR 405

SAR 465 total

includes taxes & fees

27 Oct - 28 Oct

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A modern cafe with round tables and chairs, a bar area, and a neon sign.

A bar area with a circular bar counter, multiple hanging light fixtures, and bar stools.

A modern hotel with a glass facade, multiple floors, and a prominent 'Aloft' sign.

18. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 0.8 km from Roswell Park Cancer Institute

Anthony T

SAR 823

SAR 961 total

includes taxes & fees

8 Nov - 9 Nov

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

A modern living room with a sectional sofa, a dining area, and a kitchen in the background.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

19. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.6 km from Roswell Park Cancer Institute

SAR 1,115

SAR 1,976 total

includes taxes & fees

26 Oct - 27 Oct

A buffet setup with various food items and utensils.

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".

20. Salvatores Grand Hotel

15.2 km from Roswell Park Cancer Institute

Margaret

SAR 635

SAR 722 total

includes taxes & fees

15 Oct - 16 Oct

View all properties

Compare popular hotels close to Roswell Park Cancer Institute

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 56 reviews	View
The Edward Hotel	9.6 Exceptional 268 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,006 reviews	View
Buffalo Guesthouse	9.4 Exceptional 221 reviews	View

Top Roswell Park Cancer Institute Hotel Reviews

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

8/10 Good

"I was good for one night stay!"

Best Western on the Avenue

10/10 Excellent

"Hotel was fun and quirky, with a parrot in the lobby who'd interact if she was in the mood. The included breakfast was sufficient, but not out of the ordinary. Great location!"

Buffalo Guesthouse

10/10 Excellent

"Comfy beds and friendly environment."

Lenox Hotel and Suites

10/10 Excellent

"Enjoyed our stay"

Cozy & Modern Victorian in Historic Allentown, Buffalo

10/10 Excellent

"Brandon's home was the absolute perfect location for a long weekend in Buffalo. We were able to walk just steps to one of our favorite restaurants (Gabriel's Gate), and all the bars and markets on Allen Street/Elmwood Ave.. The house had everything we needed and was decorated/furnished so nicely. The beds were super comfy, I slept like baby. The backyard garden was an oasis and I worked for two days from the table in the backyard, wifi was great! The neighbor was very nice too, which is par for the course in Buffalo. Love this city!! Go Bills."

Hilton Garden Inn Buffalo Downtown

8/10 Good

"I didn't like that it was cashless. Also the lobby coffee, while cheap, was not good."

The Westin Buffalo

10/10 Excellent

"."

Curtiss Hotel, an Ascend Collection Hotel

10/10 Excellent

"Loved it, we actually rerouted our return trip home to stay here again :)"

Unique Castle in Buffalo NY

10/10 Excellent

"The castle was clean, spacious, and one of a kind . We enjoyed our stay!"

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)

You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.

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Studio Arena Theater

Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's great live music and entertainment choices.

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Shea's 710 Theatre

You can enjoy a show at Shea's 710 Theatre during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Town Ballroom

You can make plans for a show at Town Ballroom during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Trinity Episcopal Church

You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the great live music or attend a sporting event in this family-friendly area.

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Alleyway Theatre

You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the acclaimed theater scene and great live music in this family-friendly area.

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The 9th Ward

You can make plans for a show at The 9th Ward during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Asbury Hall at Babeville

You can make plans for a show at Asbury Hall at Babeville during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Frequently asked questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 71 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

Where can I learn more about changing or cancelling my trip in the area near Roswell Park Cancer Institute?

For more details about changing or cancelling your stay near Roswell Park Cancer Institute, click here.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Find hotels near Roswell Park Cancer Institute, Buffalo from SAR 465

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Treat yourself

Be picky

Check prices for these dates

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Star rating

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Our top choices for Roswell Park Cancer Institute hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. The Mansion On Delaware Ave

5. Buffalo Guesthouse

6. Curtiss Hotel, an Ascend Collection Hotel

7. Buffalo Marriott at LECOM HARBORCENTER

8. Wyndham Garden Buffalo Downtown

9. Residence Inn by Marriott Buffalo Downtown

10. Courtyard Buffalo Downtown / Canalside

11. Best Western on the Avenue

12. Hampton Inn & Suites Buffalo Downtown

13. Hilton Garden Inn Buffalo Downtown

14. Hotel at the Lafayette Trademark Collection by Wyndham

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

16. Embassy Suites Buffalo

17. Lenox Hotel and Suites

18. Aloft by Marriott Buffalo Downtown

19. 4 Mi to Dtwn: Family Home in Buffalo

20. Salvatores Grand Hotel

Compare popular hotels close to Roswell Park Cancer Institute

Top Roswell Park Cancer Institute Hotel Reviews

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Best Western on the Avenue

Buffalo Guesthouse

Lenox Hotel and Suites

Cozy & Modern Victorian in Historic Allentown, Buffalo

Hilton Garden Inn Buffalo Downtown

The Westin Buffalo

Curtiss Hotel, an Ascend Collection Hotel

Unique Castle in Buffalo NY

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

Studio Arena Theater

Shea's 710 Theatre

Town Ballroom

Trinity Episcopal Church

Alleyway Theatre

The 9th Ward

Asbury Hall at Babeville

Frequently asked questions