Photo by Dr__Vlad

Find hotels in O Brien, FL from SAR 225

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 328 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn & Suites Alachua I-75

2.5 star property
  • Pool
  • Pet friendly
  • Parking included
  • Air conditioning
  • Gym
  • Business services
9.4 out of 10, Exceptional, (419)
  • cleanliness
    Travelers can refresh in the outdoor pool or maintain their workout routine at the gym, while the attentive staff ensures a comfortable, hassle-free stay

What verified guests said

"Great pool also"

Hampton Inn & Suites Alachua I-75 highlights

The Hampton Inn & Suites I-75 in Alachua offers a practical base with modern conveniences. Guests enjoy the outdoor pool, fitness center, and business facilities. The property provides in-room WiFi, secure luggage storage, and 24/7 front desk service with helpful staff.
The price is SAR 405
SAR 456 total
includes taxes & fees
1 Jul - 2 Jul
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

2.0 star property
  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Breakfast available
4.8 out of 10, (563)
  • cleanliness
    Guests can soak up the Florida sunshine beside the inviting outdoor pool or handle practical needs like laundry with ease - the staff is always available to assist

What verified guests said

"clean, check in easy"

Americas Best Value Inn Alachua highlights

Americas Best Value Inn Alachua offers a perfect balance of relaxation and convenience. Travelers can enjoy the outdoor pool while staying connected with complimentary in-room WiFi. The 24-hour front desk ensures someone is always available to address guest needs.
The price is SAR 236
SAR 266 total
includes taxes & fees
25 Jun - 26 Jun
Americas Best Value Inn Alachua

Royal Inn

2.0 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Laundry
  • 24/7 front desk
7.2 out of 10, Good, (177)
  • cleanliness
    A comfortable place to stay connected while enjoying attentive service from staff members who go the extra mile to ensure a memorable experience

What verified guests said

"Very convenient, clean and the beds were comfortable. Perfect for a quick sleep to rest up before hitting the road again. "

Royal Inn highlights

The Royal Inn offers a comfortable retreat with in-room WiFi. Guests praise the attentive staff and practical amenities like laundry facilities, express check-out, and an on-site vending machine.
Royal Inn

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
  • Pool
  • Hot Tub
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
9.4 out of 10, Exceptional, (1011)
  • cleanliness
    Relax in style with modern comforts like free WiFi and multilingual staff.

What verified guests said

"This is a great hotel."

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG highlights

Holiday Inn Express & Suites Alachua - Gainesville Area, an IHG Hotel offers a refreshing retreat near Ruth B. Kirby Gilchrist Blue Springs State Park. Guests can unwind in the spa tub, lounge by the outdoor pool with sun loungers, or enjoy a delicious breakfast buffet and dry cleaning/laundry services at their convenience.
The price is SAR 389
SAR 438 total
includes taxes & fees
1 Jul - 2 Jul
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Vista Verde Farm Retreat

2.0 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Microwave
  • Kitchen
10.0 out of 10, Exceptional, (5)

What verified guests said

"This is my second time staying on this property and I love it "
The price is SAR 353
SAR 641 total
includes taxes & fees
25 Jun - 26 Jun
Vista Verde Farm Retreat

BlueGem Motel

2.0 star property
  • Parking included
  • Free WiFi
  • Air conditioning
  • Microwave
  • Living/Dining area
  • Toys/Games
9.2 out of 10, Wonderful, (356)
  • cleanliness
    Travelers soak up sunshine on the welcoming terrace or enjoy evening games under the stars - the BlueGem Motel offers both relaxation and entertainment

What verified guests said

"Beautiful renovation"

BlueGem Motel highlights

The BlueGem Motel greets guests with warm hospitality and contemporary amenities. Relax on the sunny terrace or gather in the outdoor entertainment area to play games and use the barbecue grills. In-room WiFi and attentive staff enhance the comfortable, laid-back experience.
The price is SAR 380
SAR 428 total
includes taxes & fees
25 Jun - 26 Jun
BlueGem Motel

High Springs Country Inn

2.0 star property
  • Parking included
  • Free WiFi
  • Housekeeping
  • 24/7 front desk
  • Microwave
The price is SAR 296
SAR 333 total
includes taxes & fees
3 Jul - 4 Jul
High Springs Country Inn

Palms Garden Inn

2.0 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Laundry
  • Housekeeping
7.4 out of 10, Good, (546)
  • cleanliness
    Attentive staff create a welcoming atmosphere at this convenient spot near O'Leno State Park, where practical amenities like laundry facilities make stays easier

What verified guests said

"We stayed for 1 night on a long trip, and it was comfortable and dog friendly with a nice big area to run around with the dog. We would definitely stay again."

Palms Garden Inn highlights

Palms Garden Inn combines helpful service with practical comforts. Travelers appreciate the multilingual staff who ensure smooth stays, while in-room WiFi keeps everyone connected. The lobby's complimentary coffee and tea station provides a welcome pick-me-up between adventures.
The price is SAR 251
SAR 283 total
includes taxes & fees
25 Jun - 26 Jun
Palms Garden Inn

The Blanche

2.0 star property
  • Free WiFi
  • Air conditioning
  • Microwave
9.2 out of 10, Wonderful, (132)
  • cleanliness
    Travelers connect seamlessly while finding a sense of calm at this peaceful retreat in the heart of the business district

What verified guests said

"This is an absolutely beautiful historic hotel. "

The Blanche highlights

The Blanche provides a convenient stay for business travelers with in-room WiFi that keeps guests connected without hassle. This smoke-free property offers a quiet environment where visitors can truly unwind after a day of meetings.
The Blanche

Days Inn by Wyndham Lake City I-10

2.0 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
6.8 out of 10, (1002)
  • cleanliness
    Rural tranquility meets practical amenities at this Lake City retreat where guests can relax poolside or stay connected with reliable WiFi

What verified guests said

"The pool was very clean."

Days Inn by Wyndham Lake City I-10 highlights

Days Inn by Wyndham Lake City I-10 offers countryside calm with traveler essentials. Enjoy the outdoor pool, business center, to-go breakfast, free WiFi, and on-site laundry. The welcoming staff ensures a pleasant stay.
The price is SAR 252
SAR 283 total
includes taxes & fees
25 Jun - 26 Jun
Days Inn by Wyndham Lake City I-10

Postcard Cabins Gilchrist Springs

2.0 star property
  • Kitchen
  • Pet friendly
  • Parking included
  • Air conditioning
  • Outdoor Space
10.0 out of 10, Exceptional, (39)

What verified guests said

"the cabin was amazing, great amenities i would recommend!!"
The price is SAR 484
SAR 677 total
includes taxes & fees
25 Jun - 26 Jun
Postcard Cabins Gilchrist Springs

Super 8 by Wyndham Lake City

2.0 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Restaurant
7.0 out of 10, Good, (619)
  • cleanliness
    Southern comfort awaits near North Florida Speedway, where travelers can savor local cuisine, take a refreshing swim, or simply relax with in-room amenities.

What verified guests said

"Good breakfast nice pool and a great price "

Super 8 by Wyndham Lake City highlights

Super 8 by Wyndham Lake City earns praise for its genuinely helpful staff. Travelers start their day with a complimentary cooked-to-order breakfast, cool off at the outdoor pool complete with sun loungers, and stay connected using the in-room WiFi.
The price is SAR 262
SAR 294 total
includes taxes & fees
1 Jul - 2 Jul
Super 8 by Wyndham Lake City

Driftwood Inn

2.0 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Housekeeping
  • 24/7 front desk
7.8 out of 10, Good, (732)
  • cleanliness
    Comfortable surroundings and a friendly team available around the clock create a relaxing atmosphere for travelers seeking convenience and support

What verified guests said

"The guy I dealt with was really nice and helpful. The place is overpriced for the no amenities! "

Driftwood Inn highlights

The Driftwood Inn delivers comfort and relaxation with practical amenities that make a stay easier. Guests can connect to free WiFi throughout their visit, grab coffee in the lobby, and find assistance at the 24-hour front desk where helpful staff are ready to provide service.
Driftwood Inn

Regal Inn

2.5 star property
  • Parking included
  • Free WiFi
  • Housekeeping
  • 24/7 front desk
8.6 out of 10, Excellent, (501)
  • cleanliness
    Travelers find attentive service around the clock at this welcoming inn where staff members go above and beyond to create a comfortable stay

What verified guests said

"Nice new or refurbished room. If we have a chance, will stay again."

Regal Inn highlights

The Regal Inn provides a genuine retreat for weary travelers with practical amenities like in-room WiFi and complimentary self parking. Previous guests consistently mention how the helpful staff creates a memorable experience through their attentive service.
Regal Inn

Courtyard By Marriott Lake City

3.0 star property
  • Pool
  • Parking included
  • Free WiFi
  • Restaurant
  • Air conditioning
  • Breakfast available
9.6 out of 10, Exceptional, (100)

What verified guests said

"Clean, great service and nice location "
The price is SAR 394
SAR 443 total
includes taxes & fees
30 Jun - 1 Jul
Courtyard By Marriott Lake City

Days Inn by Wyndham Lake City I-75

2.0 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
7.4 out of 10, Good, (1001)
  • cleanliness
    Guests relax by the pool with a newspaper at this Lake City hotel, where simple pleasures and nature create a refreshing getaway experience

What verified guests said

"Wonderful clean room. Excellent staff and pool was clean. "

Days Inn by Wyndham Lake City I-75 highlights

Days Inn by Wyndham Lake City I-75, located in a state park, offers a peaceful retreat with continental breakfast, laundry facilities, and a swimming pool with sun loungers. Guests enjoy free newspapers and consistently praise the attentive staff.
The price is SAR 252
SAR 283 total
includes taxes & fees
30 Jun - 1 Jul
Days Inn by Wyndham Lake City I-75

Knights Inn Lake City

1.5 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Housekeeping
  • 24/7 front desk
5.4 out of 10, (624)
  • cleanliness
    Travelers appreciate the convenience of round-the-clock front desk assistance at Knights Inn Lake City, where reliable Wi-Fi keeps everyone connected

What verified guests said

"Love this place!!"

Knights Inn Lake City highlights

Knights Inn Lake City offers practical comforts and helpful service. Enjoy in-room WiFi and stress-free self-parking. The 24-hour front desk ensures assistance is always available, whether checking in late or needing local recommendations.
The price is SAR 225
SAR 253 total
includes taxes & fees
2 Jul - 3 Jul
Knights Inn Lake City

Holiday Inn & Suites Lake City by IHG

3.0 star property
  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Restaurant
  • Air conditioning
8.6 out of 10, Excellent, (1000)
  • cleanliness
    Holiday Inn & Suites Lake City offers a peaceful retreat with practical round-the-clock amenities including an indoor pool for relaxation any time of day

What verified guests said

" Nice place"

Holiday Inn & Suites Lake City by IHG highlights

Travelers find practical comforts at this IHG Hotel where the 24-hour gym and business center accommodate any schedule. The indoor pool provides a refreshing break, while The Atrium restaurant serves American dishes for guests who prefer dining on-site.
The price is SAR 371
SAR 418 total
includes taxes & fees
13 Jul - 14 Jul
Holiday Inn & Suites Lake City by IHG

Quality Inn Lake City

2.5 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
7.8 out of 10, Good, (898)
  • cleanliness
    Travelers start their day with a hearty breakfast at this welcoming inn, where an outdoor pool and fitness center help balance vacation indulgences

What verified guests said

"The staff is fantastic, however, the room had a very musty smell. "

Quality Inn Lake City highlights

Quality Inn Lake City offers genuine hospitality near Florida Gateway College. Guests enjoy a self-serve breakfast, relax by the outdoor pool, or warm up near the lobby fireplace. The property includes a gym and business center, with staff praised for their helpfulness.
The price is SAR 330
SAR 372 total
includes taxes & fees
24 Jul - 25 Jul
Quality Inn Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
8.8 out of 10, Excellent, (1005)
  • cleanliness
    Travelers start their day with convenient to-go breakfast before enjoying the indoor pool or working out anytime at the 24-hour fitness center

What verified guests said

"The staff and accomodations were great."

La Quinta Inn & Suite by Wyndham Lake City highlights

La Quinta Inn & Suites by Wyndham Lake City offers a peaceful retreat. Enjoy a to-go breakfast each morning and stay connected with in-room WiFi. The property features an indoor pool, 24/7 fitness center, and practical laundry facilities.
The price is SAR 348
SAR 391 total
includes taxes & fees
1 Jul - 2 Jul
La Quinta Inn & Suite by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about O Brien

Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢
Photo by Dr__Vlad
Open Photo by Dr__Vlad

Frequently asked questions

Where is the best place to stay in O Brien?

La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.

What's the top vacation rental in O Brien?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

Where can I learn more about changing or cancelling my trip to O Brien?

To access more information about picking new dates or cancelling your trip to O Brien, click here.

Where is the best hotel to stay near Ichetucknee Springs State Park?

Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.

What are some accommodations with pools in O Brien?
What's the best hotel for staying near Gainesville Regional Airport (GNV)?

Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.

How is it to stay in O Brien?

Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodations to choose from. Find out more about O Brien.

What should I see while I'm in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Check out what more to see and do in Expedia's O Brien guide.

What's the seasonal weather like in O Brien?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.