Photo by Dr__Vlad
Find 2 Star Hotels in O Brien, FL from SAR 217
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on O Brien 2 Star Hotels
Compare O Brien 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

La Quinta Inn & Suite by Wyndham Lake City
La Quinta Inn & Suite by Wyndham Lake City
8.8 out of 10, Excellent, (1000)
The price is SAR 368
SAR 414 total
includes taxes & fees
9 Jun - 10 Jun

Holiday Inn Express Hotel & Suites LIVE OAK by IHG
Holiday Inn Express Hotel & Suites LIVE OAK by IHG
8.4 out of 10, Very Good, (697)
The price is SAR 428
SAR 470 total
includes taxes & fees
15 Jun - 16 Jun

Best Western Plus Lake City
Best Western Plus Lake City
9.2 out of 10, Wonderful, (1004)
The price is SAR 358
SAR 402 total
includes taxes & fees
15 Jun - 16 Jun

Tru by Hilton Lake City
Tru by Hilton Lake City
9.2 out of 10, Wonderful, (1000)
The price is SAR 409
SAR 460 total
includes taxes & fees
9 Jun - 10 Jun

Comfort Suites Lake City
Comfort Suites Lake City
9.6 out of 10, Exceptional, (1003)
The price is SAR 386
SAR 435 total
includes taxes & fees
9 Jun - 10 Jun

Americas Best Value Inn Lake City
Americas Best Value Inn Lake City
8.8 out of 10, Excellent, (1003)
The price is SAR 267
SAR 300 total
includes taxes & fees
9 Jun - 10 Jun

Quality Inn Lake City
Quality Inn Lake City
7.8 out of 10, Good, (889)
The price is SAR 319
SAR 359 total
includes taxes & fees
9 Jun - 10 Jun

Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75
9.4 out of 10, Exceptional, (416)
The price is SAR 435
SAR 490 total
includes taxes & fees
15 Jun - 16 Jun
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in O Brien.

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
16367 NW 167TH BLVD, Alachua, FL
The price is SAR 439 per night from Jun 29 to Jun 30
SAR 439
SAR 494 total
29 Jun - 30 Jun
includes taxes & fees
9.2/10 Wonderful! (1,003 reviews)
Still don't see what you're looking for?
See all properties in O Brien.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about O Brien
Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

Photo by Dr__Vlad
Open Photo by Dr__Vlad
Recent reviews of O Brien hotels
Recent reviews of O Brien hotels

Americas Best Value Inn Lake City
5/5 Excellent
"Very pleased with check in. Room was clean. King bed was very comfortable, room 101"
A verified traveler stayed at Americas Best Value Inn Lake City
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
O Brien Hotels by Star Rating
Stay near popular O Brien attractions
- Hotels near Ichetucknee Springs State Park
- Hotels near Ginnie Spring
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Suwannee River State Park
- Hotels near Ichetucknee River
- Hotels near Southside Sports Complex
- Hotels near Santa Fe River
- Hotels near Lake City Mall
- Hotels near Poe Springs Park
- Hotels near Southside Recreation Complex
- Hotels near O'Leno State Park
- Hotels near North Florida Speedway
- Hotels near Columbia County Courthouse
- Hotels near Wes Skiles Peacock Springs State Park
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Lake City Columbia County Historical Museum
- Hotels near Big Shoals State Park
- Hotels near Lafayette Blue Springs State Park
- Hotels near Stephen Foster State Folk Center
- Hotels near Troy Spring State Park
Explore more hotels
- Holiday Inn & Suites Lake City by IHG
- Baymont by Wyndham Lake City
- TownePlace Suites by Marriott Lake City
- Days Inn by Wyndham Lake City I-75
- Fairfield Inn & Suites Lake City
- Americas Best Value Inn Lake City
- Hampton Inn & Suites Alachua I-75
- Quality Inn Lake City
- Days Inn by Wyndham Lake City I-10
- Americas Best Value Inn Alachua
- Home2 Suites by Hilton Lake City
- Hampton Inn & Suites Lake City
- Quality Inn White Springs Suwanee
- Gateway Inn
- Super 8 by Wyndham Lake City
- Palms Garden Inn
- Regal Inn
- BlueGem Motel
- Quality Inn & Suites Live Oak I-10 Exit 283
- Serene Live Oak Home w/ Fire Pit by River + SOSMP!