Find Resorts & Hotels with Spas in Mission District, CA

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Pick from 2 Mission District Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Front of property
Inn San Francisco
2.5 star property
9.6 out of 10, Exceptional, (480)
"Beautiful historic property with lovely garden."
The price is SAR 919
SAR 1,034 total
includes taxes & fees
26 Jum. I - 27 Jum. I
Inn San Francisco
Outdoor dining
Parker Guest House San Francisco
3.5 star property
9.4 out of 10, Exceptional, (365)
"Lovely property. Great place to chill and escape from the…"
The price is SAR 746
SAR 862 total
includes taxes & fees
24 Jum. I - 25 Jum. I
Parker Guest House San Francisco
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See all available properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Looking to vacation at a spa hotel in Mission District?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the art galleries and bars in Mission District—your day trip starts here. Be sure to pay a visit to the museums during your stay. Spa hotels are the perfect way to break away from your routine and add a layer of luxury to your vacation.
How many spa hotels are there in Mission District?
Among Expedia’s 95 accommodation options in Mission District, there are 2 spa hotels.
What's there to see and do in Mission District?
Experience Mission District with a stop at Mission Dolores Park, San Francisco Public Library, and SF Armory. If you have a little extra time during your trip, you might want to make a stop at Mission San Francisco de Asís and SOMA Pilipinas.
What is a Mission District spa hotel?
Spa hotels in Mission District provide lodging and have an on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

Recent reviews of Mission District hotels
Expedia verified reviews

Hotel Nikko San Francisco

Hotel Nikko San Francisco

5/5 Excellent
"great stuff"
A verified traveler stayed at Hotel Nikko San Francisco
Posted 16 hours ago
Hotel Nikko San Francisco