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Check prices for these dates

Tonight
15 Sep - 16 Sep
Tomorrow
16 Sep - 17 Sep
This weekend
18 Sep - 20 Sep
Next weekend
25 Sep - 27 Sep

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Our top choices for Mill Creek hotels

1. The Riverview

The Riverview
Cape Girardeau
United States
Alyssa
SAR 386
SAR 436 total
includes taxes & fees
24 Sep - 25 Sep
The Riverview

2. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
SAR 470
SAR 532 total
includes taxes & fees
24 Sep - 25 Sep
Courtyard by Marriott Cape Girardeau Downtown

3. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
United States
Joshua
SAR 282
SAR 329 total
includes taxes & fees
24 Sep - 25 Sep
Town House Inn Cape Giradreau

4. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
SAR 319
SAR 381 total
includes taxes & fees
11 Oct - 12 Oct
Candlewood Suites Cape Girardeau by IHG

5. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
SAR 397
SAR 448 total
includes taxes & fees
24 Sep - 25 Sep
Hampton Inn Cape Girardeau I 55 East

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
SAR 380
SAR 429 total
includes taxes & fees
20 Sep - 21 Sep
Fairfield Inn & Suites by Marriott Cape Girardeau

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
SAR 379
SAR 432 total
includes taxes & fees
20 Sep - 21 Sep
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

8. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
SAR 223
SAR 252 total
includes taxes & fees
21 Sep - 22 Sep
Quality Inn Cape Girardeau North

9. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
SAR 376
SAR 424 total
includes taxes & fees
20 Sep - 21 Sep
Drury Plaza Hotel Cape Girardeau Conference Center

10. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
Canada
Raidas
SAR 270
SAR 305 total
includes taxes & fees
20 Sep - 21 Sep
Pear Tree Inn Cape Girardeau West

11. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Teresa
SAR 338
SAR 381 total
includes taxes & fees
20 Sep - 21 Sep
Drury Inn & Suites Cape Girardeau

12. Makanda Inn

Makanda Inn
Makanda
United States
Michele
SAR 915
SAR 1,043 total
includes taxes & fees
17 Sep - 18 Sep
Makanda Inn
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Top Mill Creek Hotel Reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Clean room, nice comfortable beds. It was very quiet and we felt very safe. The only drawback was the toilet was too low."
Judy 1-night trip
Posted 15 hours ago
Pear Tree Inn Cape Girardeau West
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Great experience- food, cleanliness, friendly staff"
Patti 1-night trip
Posted 2 days ago
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"Excellent breakfast,friendly staff and clean rooms"
Serapia 1-night trip
Posted 3 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

10/10 Excellent
"Beautiful little cabin in a peaceful spot"
Danny P. 2-night trip
Posted 4 days ago
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

8/10 Good
"The outside needed cleaning, but the room was very clean and well maintained."
Michael p 1-night trip
Posted 11 days ago
Town House Inn Cape Giradreau
New cabin in the woods with private hot tub

New cabin in the woods with private hot tub

10/10 Excellent
"Was very nice for our first trip"
Chris E. 3-night trip
Posted 2 weeks ago
New cabin in the woods with private hot tub
Brand new cabin in the woods with hot tub  1/2 mile from Starview Winery

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

10/10 Excellent
"This is an isolated cabin that is well maintained and fairly new. nice hot tub. One draw back is that there is no internet and the smart tv is not so smart. Other than that, this is well placed next to hiking and wineries and great for a couple to get away."
Greg O. 5-night trip
Posted 3 weeks ago
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Hotel 7 Inn Anna

Hotel 7 Inn Anna

10/10 Excellent
"Staff were very accommodating and made the stay very pleasant."
Dorothy J 3-night trip
Posted 1 month ago
Hotel 7 Inn Anna
Secluded Rental Cabin on Southern Illinois Wine Trail, Private Hot Tub

Secluded Rental Cabin on Southern Illinois Wine Trail, Private Hot Tub

10/10 Excellent
"Fantastic! We will do this again!"
samantha n. 4-night trip
Posted 2 months ago
Secluded Rental Cabin on Southern Illinois Wine Trail, Private Hot Tub

More cheap stays in Mill Creek

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
SAR 223
SAR 252 total
21 Sep - 22 Sep
includes taxes & fees
Quality Inn Cape Girardeau North
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
SAR 270
SAR 305 total
20 Sep - 21 Sep
includes taxes & fees
9.2/10 Wonderful! (1,007 reviews)
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO
SAR 319
SAR 381 total
11 Oct - 12 Oct
includes taxes & fees
8/10 Very Good! (1,000 reviews)
Candlewood Suites Cape Girardeau by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
SAR 379
SAR 432 total
20 Sep - 21 Sep
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

207 S Mt Auburn Rd Cape Girardeau MO
SAR 397
SAR 448 total
24 Sep - 25 Sep
includes taxes & fees
Hampton Inn Cape Girardeau I 55 East
Hotel 7 Inn Anna

Hotel 7 Inn Anna

100 Richview Dr Anna IL
Get rates
6.6/10 (241 reviews)
Hotel 7 Inn Anna

Frequently asked questions

Where is the best place to stay in Mill Creek?
Drury Plaza Hotel Cape Girardeau Conference Center, located 18.1 mi (29.2 km) from the heart of Mill Creek, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Mill Creek.
What's the top vacation rental that Mill Creek has to offer?
On the Wine Trail Hot Tub Wi-Fi : This vacation home rental outside of Mill Creek is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Mill Creek.
If I need to cancel my hotel reservation in Mill Creek, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Mill Creek.
Where can I learn more about changing or cancelling my trip to Mill Creek?
For additional details about picking new dates or cancelling your trip to Mill Creek, head over to our customer service page.
What's it like to stay in Mill Creek?
Those traveling to Mill Creek are sure to enjoy the sights to see and things to do. There are 169 hotels and other accommodations in the surrounding area. Find out more about Mill Creek.
What are the top places to visit in Mill Creek?
Places to visit in the wider area include Trail of Tears State Park, Century Casino & Hotel Cape Girardeau, and Hunter Valley Winery. You'll also find Lower Cache River Access Area and Henry N Barkhausen Cache River Wetlands Center in the area. Check out what more to see and do in Expedia's Mill Creek guide.
What's the seasonal weather like in Mill Creek?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 39°F. Average annual precipitation for Mill Creek is 56 inches.