Find Resorts & Hotels with Spas in Main Street Hyannis, MA
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Main Street Hyannis Resorts & Hotels with Spas
Pick from 2 Main Street Hyannis Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.
Comfort Inn Hyannis - Cape Cod
Comfort Inn Hyannis - Cape Cod
7.6 out of 10, Good, (1007)
The price is SAR 484
SAR 554 total
includes taxes & fees
12 Jum. II - 13 Jum. II
Hyannis Plaza Hotel
Hyannis Plaza Hotel
6.8 out of 10, (530)
The price is SAR 375
SAR 461 total
includes taxes & fees
12 Jum. II - 13 Jum. II
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent reviews of Main Street Hyannis hotelsExpedia verified reviews
5/5 Excellent
Great stay
"Great location and very friendly staff."
A verified traveler stayed at Sea Crest Beach Resort
Posted 1 day ago
More Hotel Options in Main Street Hyannis
- Adventure Hotels (4)
- Beach Hotels (4)
- Business Hotels (4)
- Cheap Hotels (4)
- Family Hotels (4)
- Golf Hotels (4)
- Historic Hotels (4)
- Hotel Wedding Venues (2)
- Hotels with Bars (4)
- Hotels with Free Parking (4)
- Hotels with Hot Tubs (2)
- Hotels with WiFi (4)
- Hotels with a Pool (4)
- Hotels with an Indoor Pool (2)
- Hotels with smoking rooms (1)
- Luxury Hotels (4)
- Romantic Hotels (3)
- Shopping Hotels (4)
- Winery Hotels (4)
More Accommodation Types in Main Street Hyannis
- Vacation Homes in Hyannis (3,011)
- Cottages in Hyannis (498)
- Condo Rentals in Hyannis (207)
- Apartments in Hyannis (175)
- B&B in Hyannis (72)
- Motels in Hyannis (64)
- Aparthotels in Hyannis (23)
- Resorts in Hyannis (18)
- Guest Houses in Hyannis (15)
- Inns in Hyannis (4)
- Condo Resorts in Hyannis (2)
- Hostels in Hyannis (2)
Hotels near popular Hyannis Attractions
- Hotels near John F. Kennedy Hyannis Museum
- Hotels near Cape Cod Baseball Hall of Fame
- Hotels near Cape Cod Carousel
- Hotels near Wackenhammer's Clockwork Arcade
- Hotels near Hyannis Harbor
- Hotels near Cape Cod Melody Tent
- Hotels near Cape Cod National Seashore
- Hotels near Cape Cod Inflatable Park
- Hotels near Island Queen Ferry
- Hotels near West Dennis Beach
Main Street Hyannis Hotels by Star Rating
Explore more hotels
- Admiralty Inn & Suites - a Red Collection Hotel
- Cape Codder Resort and Spa
- Comfort Inn Hyannis - Cape Cod
- Riviera Beach Resort
- Anchor In Distinctive Waterfront Lodging
- Ambassador Inn & Suites
- The Mansion at Ocean Edge
- Best Western Cape Cod Hotel
- Falmouth Inn
- Hyannis Harbor Hotel
- Wequassett Resort and Golf Club
- All Seasons Resort, Trademark Collection by Wyndham
- Courtyard By Marriott Cape Cod Hyannis
- Holiday Hill Inn & Suites
- Falmouth Tides
- Sandwich Lodge & Resort
- The Dan'l Webster Inn and Spa
- AutoCamp Cape Cod
- Tidewater Inn
- Sandwich Inn and Suites