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Check prices for these dates

Tonight
13 Nov - 14 Nov
Tomorrow
14 Nov - 15 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

Top Irene Hotel Reviews

A Fairfield by Marriott hotel with a modern design, featuring a prominent entrance and a stone facade.
Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton
Yankton

10/10 Excellent

The staff was amazingly nice and helpful!!!! Would have given 10 stars for service if I could.
United States
Heidi
Reviewed October 29, 2026
Fairfield Inn & Suites by Marriott Yankton

Frequently Asked Questions

What are some of the best vacation rentals that Irene has to offer?

Charming Lake House within Walking Distance from Lake: This vacation home rental near Irene is located on a lake and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Irene.

If I need to cancel my hotel reservation in Irene, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Irene.

Where can I learn more about changing or cancelling my trip to Irene?

To find more details about rescheduling or cancelling your trip to Irene, go to https://www.expedia.com/service/.

What is the best hotel near Sioux Falls Regional Airport (FSD)?

AeroStay Hotel is a popular hotel, featuring free breakfast and free WiFi. It's located a short 0.1 mi (0.1 km) from Sioux Falls Regional Airport. Other good options close to the airport are Ramada by Wyndham Sioux Falls Airport Hotel & Suites and AmericInn by Wyndham Sioux Falls North.

What is staying in Irene like?

Travelers to Irene will find plenty to explore and enjoy. There are 65 hotels and other accommodations in the surrounding area. Find out more about Irene.

What should I see while I'm in Irene?

Places to visit in the wider area include Fox Run Plaza, Fantle Memorial Park, and G.A.R. Hall. You'll also find Lincoln Park and Aviation Park in the area. Check out what more to see and do in Expedia's Irene guide.

What's the weather like in Irene?

The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in Irene are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.

What's the best place for a stay in Irene?

Comfort Inn Yankton SD, located 18 mi (29 km) from the heart of Irene, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Lewis and Clark Resort and Econo Lodge Inn & Suites Yankton. See all available top hotels, or vacation rentals in Irene.