Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening at George R. Brown Convention Center, a top convention center in Houston. Experience the lively festivals and great live music in this vibrant area.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the acclaimed theater scene and great live music in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed theater scene and entertainment choices in this vibrant area.
Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's fascinating museums and acclaimed art scene.
University of Houston
Enjoy the collegiate vibe around University of Houston, a top university in Houston. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
South Main Hotel Deals
Reviewed on 13 July 2025
Reviewed on 13 July 2025
Reviewed on 12 July 2025
Reviewed on 12 July 2025
Reviewed on 12 July 2025
Reviewed on 14 July 2025
Other neighborhoods around South Main
Astrodome
If you're spending time in Astrodome, check out sights like NRG Stadium or NRG Arena and hop on the metro to see more the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
Houston Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Houston Museum District. You can visit top attractions like Houston Zoo and Children's Museum of Houston, and jump on the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Houston Zoo or Children's Museum of Houston and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
- NRG Stadium
- George R. Brown Convention Center
- MD Anderson Cancer Center
- Daikin Park
- Toyota Center
- Rice University
- University of Houston
- Houston Zoo
- Westheimer Rd
- Memorial City Mall
- Downtown Aquarium
- CityCentre
- NRG Park
- Smart Financial Centre at Sugar Land
- Sugar Land Town Square
- NRG Center
- Houston Natural Science Museum
- Baybrook Mall
- Texas Southern University
- Discovery Green
- Hobby Center for the Performing Arts
- Sam Houston Race Park
- House of Blues Houston
- Houston Methodist Hospital
- Pearland Town Center
- The Galleria
- Children's Museum of Houston
- Greenspoint Mall
- Greenway Plaza
- Lakewood Church
- Memorial Hermann Memorial City Medical Center
- Memorial Park