Search Apartments in Defiance

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Apartments in Defiance

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

2.0 star property
8.6 out of 10, Excellent, (13)
"The property was quiet and as expected. They were incredibly responsive and helpful with everything. "
The price is SAR 253
SAR 516 total
includes taxes & fees
25 Jun - 26 Jun
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

The Lofts of North Main Street

9.6 out of 10, Exceptional, (138)
"This is our 2nd time staying here for a girls weekend, and it is perfect."
The price is SAR 436
SAR 928 total
includes taxes & fees
17 Jun - 18 Jun
The Lofts of North Main Street

Overlook Main St. in this 2 Bedroom Owners Suite!

4.0 star property
9.6 out of 10, Exceptional, (25)
"Perfect place for a visit to St Charles! Hope to return and stay here again!"
Overlook Main St. in this 2 Bedroom Owners Suite!

The Hidden Gem - 2BR Basement Apartment on 7 Acres

10.0 out of 10, Exceptional, (11)
"Another great stay at The Hidden Gem. Easy access in a quiet location!"
The Hidden Gem - 2BR Basement Apartment on 7 Acres

Zia New Haven

3.5 star property
9.8 out of 10, Exceptional, (7)
"The property was well kept up and the owners provided everything you could need for a comfortable stay. Laura is very sweet and made us feel very welcome for our 25th wedding anniversary. I highly recommend staying here. The town is small but it is only a short distance to wineries, distilleries and many other things of interest. "
Zia New Haven

Prime Loft of Main Street

9.8 out of 10, Exceptional, (88)
"Fantastic place and location!"
The price is SAR 436
SAR 928 total
includes taxes & fees
17 Jun - 18 Jun
Prime Loft of Main Street

Private Basement Retreat w/ HOT TUB by StayLage

9.0 out of 10, Wonderful, (7)
"It is absolutely beautiful. The room is huge it's super clean the hot tub was so nice the little back patio is stunning we spent our honeymoon here and 10 out of 10 recommend here "
The price is SAR 345
SAR 981 total
includes taxes & fees
17 Jun - 18 Jun
Private Basement Retreat w/ HOT TUB by StayLage

Sunny SparkingClean King bed Apt- CreveCoeurPark

9.6 out of 10, Exceptional, (10)
"Good Stay"
The price is SAR 383
SAR 852 total
includes taxes & fees
14 Jul - 15 Jul
Sunny SparkingClean King bed Apt- CreveCoeurPark

Cozy country setting 4 miles from route 66

10.0 out of 10, Exceptional, (6)
"Really nice property! Country setting and nice big living area."
The price is SAR 563
SAR 880 total
includes taxes & fees
17 Jun - 18 Jun
Cozy country setting 4 miles from route 66

Cozy Clark Suite in Frenchtown Saint Charles

9.0 out of 10, Wonderful, (2)
Cozy Clark Suite in Frenchtown Saint Charles

Swim, Fish, Hike, Horseback

9.6 out of 10, Exceptional, (55)
"We rented the property to be in the area for the holiday. The house had plenty of sleeping spaces and linens. The kids were enjoyed seeing the horses on the property. "
Swim, Fish, Hike, Horseback

Remodeled Kirkwood Guest house

10.0 out of 10, Exceptional, (71)
"A cozy and immaculately kept guest house at a great location. Close to everything. Great hosts ready to answer all your questions. I really enjoyed my stay and will definitely be back."
Remodeled Kirkwood Guest house

Charming Duplex on Main

10.0 out of 10, Exceptional, (12)
"Everything was awesome!!!!!!"
The price is SAR 466
SAR 1,120 total
includes taxes & fees
22 Jun - 23 Jun
Charming Duplex on Main

Studio on Historic Main by StayLage

9.2 out of 10, Wonderful, (24)
"A great location and close to the Katy Trail."
The price is SAR 365
SAR 891 total
includes taxes & fees
17 Jun - 18 Jun
Studio on Historic Main by StayLage

The Historic Bricks on Main

9.6 out of 10, Exceptional, (10)
"Loved the property and location. Able to walk to all the shops, restaurants, bars etc. "
The price is SAR 385
SAR 895 total
includes taxes & fees
24 Jun - 25 Jun
The Historic Bricks on Main

Main Street Living! 2 Bedroom Unit right On Main!

10.0 out of 10, Exceptional, (26)
"Perfect location. Very clean. Would highly recommend!"
The price is SAR 608
SAR 1,630 total
includes taxes & fees
17 Jun - 18 Jun
Main Street Living! 2 Bedroom Unit right On Main!

Western-Themed 2-Bedroom Hideout for Outlaws 204-2

9.2 out of 10, Wonderful, (9)
"Fun little place, clean and great location!"
Western-Themed 2-Bedroom Hideout for Outlaws 204-2

Lovely Couples Escape on Mississippi River!

10.0 out of 10, Exceptional, (14)
"We had a great weekend getaway at this property. Beautiful view of the river and peaceful! We hope to return!"
Lovely Couples Escape on Mississippi River!

Spacious 2-Bedroom Near Main St by StayLage

8.6 out of 10, Excellent, (12)
"We are grateful for our comfortable stay, and the location felt safe as well as close to everything."
The price is SAR 389
SAR 1,061 total
includes taxes & fees
22 Jun - 23 Jun
Spacious 2-Bedroom Near Main St by StayLage

Bold 2324 I Parking I Pool I Gym I Parking

2.0 star property
Bold 2324 I Parking I Pool I Gym I Parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You’ll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Listed below are some of the more popular apartments in the area to choose from: ‘The Ruebling House’ Cozy Defiance Apartment!: Includes private yards. Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Access to onsite laundry facilities is available on site. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues: Located in Ballwin, 14.1 mi/22.7 km away. Includes Smart TVs. Access to onsite laundry facilities is available on site. The Lofts of North Main Street: Located 19.2 mi/30.8 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Access to onsite laundry facilities is available on site. Cozy Clark Suite in Frenchtown Saint Charles: It’s located in St. Charles, 19.6 mi/31.6 km from Defiance. Includes free WiFi, private balconies, and separate dining areas.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you’re planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you’d like to explore around the area, you may want a rental car for your journey.