A bridge over a body of water with several boats.

Find hotels in San Francisco, Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for San Francisco hotels

1. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,316 reviews)
"Great location, helpful staff, efficient check-in and check-out, good breakfast, clean property, free parking"
United States
Bettyanne
The price is SAR 399
SAR 439 total
includes taxes & fees
5 Sep - 6 Sep
Ramada Plaza by Wyndham Panama Punta Pacifica

2. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,017 reviews)
"Everything inside hotel was clean, food at the bar was excellent and the service as well. Location of the hotel was central to other places."
United States
Agustin Francisco
The price is SAR 444
SAR 488 total
includes taxes & fees
6 Sep - 7 Sep
Courtyard by Marriott Panama Multiplaza Mall

3. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,012 reviews)
"Nice hotel, rooms are comfortable and clean. Breakfast is ok with some alternatives"
United States
Mauricio
The price is SAR 497
SAR 546 total
includes taxes & fees
28 Aug - 29 Aug
Aloft by Marriott Panama

4. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,005 reviews)
"Hotel was clean and staff was very helpful."
United States
Benjamin A
The price is SAR 1,018
SAR 1,120 total
includes taxes & fees
11 Sep - 12 Sep
JW Marriott Panama

5. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,001 reviews)
"Super staff Overall excellent hotel"
United States
Luis
The price is SAR 659
SAR 725 total
includes taxes & fees
3 Sep - 4 Sep
Sheraton Grand Panama

6. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,232 reviews)
"Great breakfast, location excellent, staff friendly and spacious room"
United States
Gilberto
The price is SAR 431
SAR 474 total
includes taxes & fees
21 Sep - 22 Sep
Plaza Paitilla Inn Hotel

7. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,094 reviews)
"Great location, staff were always helpful and welcoming. Property is well maintained and clean. Will stay here again"
United States
Saskia
The price is SAR 645
SAR 710 total
includes taxes & fees
13 Sep - 14 Sep
Las Americas Golden Tower Panama

8. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,712 reviews)
"Good environment , stuff etc and the location very close to the malls , and other restaurants"
United States
Clive Dwayne
The price is SAR 422
SAR 464 total
includes taxes & fees
22 Sep - 23 Sep
Decapolis Hotel Panama City

9. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (664 reviews)
"Everything was perfect, breakfast was good with many options and the fruits amazing, staff are very friendly and helpful, I really recommend this hotel."
United States
Frank David Delgado
The price is SAR 774
SAR 851 total
includes taxes & fees
30 Aug - 31 Aug
Residence Inn by Marriott Panama City

10. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (61 reviews)
"I enjoyed my stay, during my one night layover in Panama City. The apartment was beautiful, cozy and charming - just like in the pictures. It was a little hard to find, because it’s in a residential building and not a hotel - but the staff was responsive and kind."
United States
Claire
The price is SAR 379
SAR 521 total
includes taxes & fees
23 Aug - 24 Aug
San Francisco by Wynwood House

11. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,686 reviews)
"Shops close by at reasonable rates and good breakfast."
United States
Mark
The price is SAR 515
SAR 515 total
includes taxes & fees
4 Sep - 5 Sep
Megapolis Hotel Panamá

12. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.4 out of 10, Very Good, (25 reviews)
"Exactly like the photos was very nice"
Canada
Jessica
The price is SAR 501
SAR 553 total
includes taxes & fees
29 Aug - 30 Aug
Dovle Residences by HMS-Preferred Member

13. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (220 reviews)
"Great location"
United States
Hugo
The price is SAR 131
SAR 671 total
includes taxes & fees
23 Aug - 24 Aug
Boutique Apartments Panamá Coco del Mar

14. Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is SAR 442
SAR 487 total
includes taxes & fees
24 Aug - 25 Aug
Modern Apartments at the Hub City views

15. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very Good, (48 reviews)
"Excellent apartment and service."
United States
Dustin M
The price is SAR 144
SAR 569 total
includes taxes & fees
23 Aug - 24 Aug
Boutique Apartments Atlapa

16. Modern Apartments PH Living 73 SF

Modern Apartments PH Living 73 SF
3.5 star property
San Francisco
7.4 out of 10, Good, (3 reviews)
"To the owner, it would help if the top sheet is larger than the bed, difficult for two people to cover themselves"
United States
Dawid
The price is SAR 301
SAR 331 total
includes taxes & fees
30 Aug - 31 Aug
Modern Apartments PH Living 73 SF

17. Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
7.8 out of 10, Good, (14 reviews)
"This is a great place to stay. It's super comfortable and private. No noises from the exterior. The staff was very friendly and professional. I 100 % recommend Casa Orquídea."
United States
Fernando
The price is SAR 297
SAR 327 total
includes taxes & fees
2 Sep - 3 Sep
Casa Orquídea

18. w Engaging 1BR w Balcony in San Francisco

w Engaging 1BR w Balcony in San Francisco
2.0 star property
San Francisco
The price is SAR 345
SAR 495 total
includes taxes & fees
23 Aug - 24 Aug
w Engaging 1BR w Balcony in San Francisco

19. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is SAR 267
SAR 869 total
includes taxes & fees
20 Sep - 21 Sep
Wanders Panama by Boutique Apartments

20. Wanders & Yoo

Wanders & Yoo
4.0 star property
San Francisco
8.0 out of 10, Very Good, (11 reviews)
"Cool and modern condos, great location and views."
United States
Jorge
The price is SAR 1,176
SAR 1,294 total
includes taxes & fees
7 Sep - 8 Sep
Wanders & Yoo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast, lunch and dinner served
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6
Exceptional
1,316 reviews
View
Exterior
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
9.0
Wonderful
1,017 reviews
View
Exterior
Aloft by Marriott Panama
3.5 star property
8.8
Excellent
1,012 reviews
View
Terrace/patio
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,232 reviews
View
Front of property
Decapolis Hotel Panama City
4.0 star property
8.6
Excellent
1,712 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Top San Francisco Hotel Reviews

Find out more about San Francisco

Top reasons to visit San Francisco

  • Stunning Ocean Views: Enjoy breathtaking coastal scenery that captivates every visitor.
  • Diverse Cultural Experiences: Explore vibrant streets and immerse yourself in local art and traditions.
  • Beautiful Urban Parks: Relax in scenic parks perfect for picnics and outdoor activities.
  • Family-Friendly Attractions: Discover a variety of attractions and activities suitable for all ages.
  • Variety of Accommodations: Choose from luxurious hotels to budget hostels, catering to every traveler's needs.

Find great hotels near San Francisco

Discover a diverse selection of accommodations in San Francisco, Panama, ideal for every type of traveler. Whether you're seeking luxurious hotels, budget-friendly hostels, or family-oriented stays, you'll find options that cater to your needs. The area is particularly suited for business travelers, featuring top-notch services and facilities. Explore the best hotels and unforgettable experiences that San Francisco has to offer, ensuring a memorable vacation for you and your loved ones.

  • Hotel Riu Plaza Panama: Nestled just 1.6km from San Francisco, Hotel Riu Plaza Panama is a 4-star haven for adventure seekers and business travelers alike. This vibrant property offers a range of exciting adventure sports and recreational activities both on-site and nearby, making it perfect for those looking to blend work with play. Guests can expect modern accommodations equipped with all the necessary amenities to ensure a comfortable stay, along with excellent dining options that cater to diverse tastes.
  • Novotel Panama City: Ideal for families and business travelers, Novotel Panama City is a welcoming 4-star hotel located a mile from San Francisco. This family-friendly establishment is designed with children in mind, featuring complimentary cribs, a dedicated children's club, and a playful playground area. The hotel ensures that parents can enjoy their stay while their kids are entertained, making it a perfect choice for family vacations. With spacious rooms and a variety of amenities, Novotel provides a comfortable and convenient base for exploring the vibrant city.
  • Plaza Paitilla Inn Hotel: Located in the heart of the city and just 1.6km from San Francisco, Plaza Paitilla Inn Hotel is a charming 3.5-star retreat that caters to couples and business travelers. This romantic hotel offers exclusive romance packages, perfect for a special getaway. Guests can indulge in delightful dining experiences through limited-hour room service and unwind together at the spa or pool, with amenities like reflexology treatments and sun loungers. The intimate atmosphere and central location make it an excellent choice for a memorable stay.

Where to stay near San Francisco

San Francisco offers a delightful blend of experiences for every traveler. Explore the vibrant atmosphere of Panama City, with its mix of historical charm and modern luxury. Enjoy a weekend getaway in nearby Downtown San Rafael, where friendly locals and recreation opportunities abound. Whether you're seeking a family-friendly adventure or a business-themed trip, San Francisco and its surroundings provide the perfect backdrop for an unforgettable vacation.

  • Panama City: A vibrant urban hub, Panama City is a fascinating blend of modern skyscrapers and historic neighborhoods. As the capital of Panama, it is located along the Pacific coast and serves as a gateway to the Panama Canal. Travelers flock to Panama City year-round for family-friendly activities, business opportunities, and cultural experiences. You can explore bustling shopping malls, local markets, and enjoy the beautiful beaches and parks nearby. The city's rich history and diverse culture make it a must-visit destination, with attractions like the historic Casco Viejo and the iconic Panama Canal just a short distance away.
  • Obarrio: Situated less than 1.6km from San Francisco, Obarrio is a thriving neighborhood known for its upscale shopping and business environment. This area attracts visitors looking for a blend of family, city-themed, and business experiences. Here, you'll find a variety of shopping centers and malls, making it a perfect spot for those looking to indulge in retail therapy. Obarrio's proximity to parks and tourist precincts adds to its charm, inviting travelers to unwind in green spaces while enjoying the urban atmosphere. The neighborhood’s dynamic vibe and convenient location make it an appealing stop on your journey.
  • Bella Vista: Located about a mile from San Francisco, Bella Vista is a lively neighborhood that captures the essence of city life in Panama. Known for its family-friendly atmosphere and numerous business opportunities, Bella Vista offers visitors an array of shopping options, including prominent shopping malls and centers. With beautiful parks and vibrant streets, it’s an ideal area for leisurely strolls and exploration. The neighborhood's rich cultural landscape and accessibility to various attractions ensure that travelers will have an engaging and enjoyable experience during their stay.

Things to do in and around San Francisco

San Francisco is perfect for family vacations or business trips, offering a blend of memorable experiences. Visitors can enjoy stunning ocean views and explore various shopping malls and centers, ideal for a day out. The city also features beautiful picnic areas, making it a great spot for relaxation. Whether you're seeking adventure or leisure, San Francisco has something for everyone.

Shopping

In San Francisco, you can shop at Multiplaza Pacific Mall and Multicentro Panama, both offering a vibrant mix of business, entertainment, and family-friendly vibes. If you're willing to travel a mile, visit Pacific Center for more shopping options and local finds.

Recreation

In San Francisco, visit Estadio Rommel Fernandez, Estadio Nacional Rod Carew, and Maracana Stadium, all within 6.4km, for energetic sports vibes and engaging activities. These venues offer an exciting atmosphere for both sports enthusiasts and those looking to recharge through active participation.

Adventure

Hike Honeycreeper Ridge Trail, located 37.0km from San Francisco, where you'll enjoy breathtaking scenery and immerse yourself in nature's adventure vibes. Experience the thrill of ziplining at Gatun Eco Adventures, 46.7km away, surrounded by lush landscapes and outdoor excitement.

Nightlife

Experience the vibrant nightlife in San Francisco with a visit to the National Theater, Anita Villalaz Theater, and Theater Circle, all offering a blend of romance, entertainment, and cultural vibes. Each venue promises a unique atmosphere, perfect for a memorable evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for San Francisco

To save money during your trip to San Francisco, visit between September and November when prices are lower, and opt for a Tuesday stay to avoid peak Saturday rates. Utilize Expedia to find budget-friendly accommodations, especially eco-certified hotels. Consider booking a package that combines your hotel, flights, and activities for additional discounts. For public transportation, use the Muni system, which is cost-effective and reliable. Lastly, explore free activities like visiting Golden Gate Park or walking along the waterfront to enjoy the city's sights without spending a dime.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around San Francisco are September to November, where the prices are slightly lower. This is in comparison to January and March to April, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around San Francisco is Tuesday. The most expensive day to stay around San Francisco is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to customize your options based on your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and environmentally-friendly hotels that are currently available. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in San Francisco with your flights and activities by booking an Expedia package.

Find the best attractions near San Francisco

San Francisco offers a diverse vacation experience suitable for families, business travelers, and culture enthusiasts alike. Explore its vibrant streets, beautiful urban parks, and various event venues that cater to a wide range of interests. Whether you're looking for cultural experiences or business opportunities, San Francisco has something for everyone. Don't miss the chance to visit local attractions like Santa Maria while enjoying the unique charm of this iconic city.

  • Cinta Costera: This urban park stretches along the waterfront, offering stunning views of the bay and skyline. Perfect for families, the park features walking and biking paths, playgrounds, and green spaces, making it an ideal spot for relaxation and recreation.
  • Avenida Balboa: Renowned for its vibrant city atmosphere, Avenida Balboa is a bustling street lined with shops, restaurants, and scenic views of the ocean. It's a popular place for both locals and tourists to stroll, dine, and soak in the lively ambiance of Panama City.
  • Panama Viejo: As a UNESCO World Heritage site, Panama Viejo offers a glimpse into the rich history and culture of the region. Explore the ruins of the original city, including ancient churches and fortifications, while learning about its fascinating past.

Best time to go to San Francisco

The best time to visit San Francisco can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around San Francisco falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around San Francisco falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudyAverageAverage
July79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudySlightly LowSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly LowAverage

The nearest major airports for your trip to San Francisco

Traveling to San Francisco can be convenient with several major airports nearby. Tocumen International Airport (PTY) is 16.1km away, with luxury accommodations like The Santa Maria, a 5-star hotel located 8.0km from the airport. Marcos A. Gelabert International Airport (PAC) is closer at 6.4km, offering hotels like Sofitel Legend Casco Viejo, just 3.2km away. Balboa Airport (BLB) is 12.9km from San Francisco, with options like Hilton Panama, located 9.7km from the airport. Transportation services include airport shuttles and transfers available at these hotels, providing easy access to and from the airports.

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on our traveler data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Aloft by Marriott Panama and Courtyard by Marriott Panama Multiplaza Mall.
How many hotels will I find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 328 San Francisco hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.
What is there to do in this Panama City neighborhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Via Espana, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Pacific Center. When you're sightseeing in Panama City, Soho City Center and National Shrine of the Heart of Mary are also worth a stop.