Find Resorts & Hotels with Spas in Chillicothe, MO

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Pick from Chillicothe Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Frequently asked questions

Looking for a spa hotel in Chillicothe?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the natural parks in Chillicothe - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Chillicothe?
Among Expedia’s 10 accommodation options in Chillicothe, there are 2 spa hotels.
What's there to see and do in Chillicothe?
Experience Chillicothe with a stop at Chillicothe Country Club, Green Hills Golf Course, and Daryl Danner Memorial Park. If you have spare time during your trip, you might want to make a stop at Pershing State Park and Black Silo Winery.
What is a Chillicothe spa hotel?
Spa hotels in Chillicothe provide lodging and have an on-site spa offering services like therapies and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

Recent reviews of Chillicothe hotels
Expedia verified reviews

Quality Inn & Suites Bethany

Quality Inn & Suites Bethany

5/5 Excellent
Stay in Bethany Quality Inn
"As others mention, they do a $100 deposit for "incidents". We had a single king bedroom. We were impressed by having the extra space as we were easily able to set up 2 pack-n-plays for our kids. Room was very clean. Pillows were what you expect as well as bed. Nothing to brag about, but did the trick for the night. Didn't use pool. Breakfast was typical for a Choice hotel with cereal, some bakery items, bananas, yogurt, and hot food of biscuits, cream of mushroom for gravy with biscuits, eggs, and sausage links. Easy on/off of interstate. Worked great for family of 4."
A verified traveler stayed at Quality Inn & Suites Bethany
Posted 3 days ago
Quality Inn & Suites Bethany
Comfort Inn Marshall Station

Comfort Inn Marshall Station

5/5 Excellent
"This a beautiful place to stay. Very very clean staff is great place is beautiful inside and out.i stay here when I visit my son at Missouri Valley College!"
A verified traveler stayed at Comfort Inn Marshall Station
Posted 1 month ago
Comfort Inn Marshall Station