Find Hotels near Cairo Regional Airport (CIR)

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    one key icon
    Treat yourself
    Save instantly and earn perks with One Key
    Learn about One Key
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveler experience
Traveler experience

Compare hotels near Cairo Regional airport with room rates, reviews, and updated availability. Most hotels are fully refundable.

Exterior
Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, (224)
"Good bang for your buck! Price through the app was on point and $25 less than going through the hotel..Room was clean zero complaints on cleanliness except for the carpet that you could feel moisture in which also made the hallway and rooms smell..Get rid of the carpet and put down laminate and I’m pretty sure the smell would go away! "
The price is SAR 300
SAR 328 total
includes taxes & fees
28 Jum. I - 29 Jum. I
Quality Inn Cairo I-57
The Labrador Room
Cozy cabins on beautiful Horseshoe Lake
9.8 out of 10, Exceptional, (18)
"We were looking for a place to view the 2024 solar eclipse and we found this cabin, which was in the path of totality! We were so excited to be able to view the eclipse from the property, which meant that we didn't have to deal with traffic getting home or to other lodging. Sherry was a great host. The cabin was quiet and clean. and just perfect for a two-night stay. "
The price is SAR 431
SAR 506 total
includes taxes & fees
27 Jum. I - 28 Jum. I
Cozy cabins on beautiful Horseshoe Lake
Room
The Rested Duck Mallard Room
8.8 out of 10, Excellent, (14)
"Lovely, unexpected gem! I would love to come back again!"
The price is SAR 431
SAR 536 total
includes taxes & fees
27 Jum. I - 28 Jum. I
The Rested Duck Mallard Room
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.8 out of 10, (498)
"It was fine, nothing exceptional"
The price is SAR 246
SAR 273 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior
Eagle Inn Charleston
2.0 star property
6.8 out of 10, (93)
"Simple but clean. Bathroom door would not close due to water damage on bottom. This was only issue. Comfortable sleeping "
The price is SAR 264
SAR 293 total
includes taxes & fees
27 Jum. I - 28 Jum. I
Eagle Inn Charleston
Exterior
Quality Inn - Sikeston
2.5 star property
6.8 out of 10, (326)
"Everything was very nice it was a quick pit.stop on a long trip but was clean and they upgraded our room at no extra charge when we got there"
The price is SAR 237
SAR 256 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Quality Inn - Sikeston
Front of property
La Center Motel
2.0 star property
6.0 out of 10, (3)
"Very good. It’s an older motel but the new owners are repairing and upgrading units. Staff was willing to assist in any way, eager to please. Highly recommend."
The price is SAR 244
SAR 281 total
includes taxes & fees
25 Jum. I - 26 Jum. I
La Center Motel
Aerial view
Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024.
The price is SAR 150
SAR 225 total
includes taxes & fees
28 Jum. I - 29 Jum. I
Solar Eclipse Festival at our Campground at Benton Speedway. April 6-8th 2024.
Aerial view
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.
10.0 out of 10, Exceptional, (1)
"As described. Happy with the experience for the eclipse."
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.
Room
Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.0 out of 10, Good, (1004)
"Great value and super quiet. "
The price is SAR 255
SAR 284 total
includes taxes & fees
30 Jum. I - 31 Jum. I
Days Inn and Suites by Wyndham Sikeston
Pool
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1000)
"Convenient location and newer facility compared to other area options."
The price is SAR 371
SAR 421 total
includes taxes & fees
9 Jum. II - 10 Jum. II
Drury Inn & Suites Sikeston, MO
Exterior
Beautiful Cabin Retreat
8.2 out of 10, Very Good, (39)
"Host had the cabin very clean. New leather couch & recliner. Mattress was extremely comfortable. Washer & Dryer were excellent. Another Rental house near, long-term renters were very quiet. Internet not very good in the Illinois woods. Closed cabin has a musty smell from humidity in the woods. Host had an automatic air freshener going to help with air quality."
The price is SAR 450
SAR 728 total
includes taxes & fees
25 Jum. I - 26 Jum. I
Beautiful Cabin Retreat
Exterior
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1002)
"Just a rest stop"
The price is SAR 354
SAR 406 total
includes taxes & fees
28 Jum. I - 29 Jum. I
Pear Tree Inn Sikeston
Exterior
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, (1002)
"No comment"
The price is SAR 412
SAR 459 total
includes taxes & fees
24 Jum. II - 25 Jum. II
Best Western Plus Sikeston
Room
Travel Inn & Suites
2.5 star property
8.4 out of 10, Very Good, (523)
"Would stay again. Nice and clean. "
The price is SAR 257
SAR 291 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Travel Inn & Suites
Exterior
Country Yard Inn and Suite
2.0 star property
7.6 out of 10, Good, (32)
"Considering the price of the room, it was adequate. Thankfully it was a cooler weekend (the previous week had been uncharacteristically warm) or we would have had to move rooms due to an inadequate air conditioning unit. That being said, it was a clean room and the bed was comfortable. The motel is convenient to the interstate and the main road into Sikeston. Our room was at the far end of the motel, so away from any interstate noise."
The price is SAR 208
SAR 231 total
includes taxes & fees
1 Jum. II - 2 Jum. II
Country Yard Inn and Suite
Front entrance in spring. A new metal roof was installed in October of 2018.
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
10.0 out of 10, Exceptional, (138)
"This was our third time booking this home on VRBO. We always enjoy our stay here, and this time was no different. It’s a very cozy home to stay in. We never spend much time here throughout the day since we always come up from Texas to visit family here locally, however we are here overnights. The beds are very comfortable, and it’s very spacious and quiet. They are pet friendly and since we never travel without our dogs, it makes it very nice to book here. We plan to return again next Spring."
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Exterior
Comfort Inn & Suites Sikeston I-55
2.5 star property
8.4 out of 10, Very Good, (197)
"Place was great"
The price is SAR 382
SAR 433 total
includes taxes & fees
2 Jum. II - 3 Jum. II
Comfort Inn & Suites Sikeston I-55
Charming cottage overlooking Lake Acre
10.0 out of 10, Exceptional, (84)
"What a cute property that is nicely furnished and very comfortable. Suzie was a great host and we’d definitely book this place again."
The price is SAR 563
SAR 960 total
includes taxes & fees
29 Jum. I - 30 Jum. I
Charming cottage overlooking Lake Acre
Exterior
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
6.4 out of 10, (471)
"It was by the outlet store"
The price is SAR 226
SAR 252 total
includes taxes & fees
30 Jum. I - 31 Jum. I
Super 8 by Wyndham Sikeston/Miner Area
Don't see what you're looking for?
See all available properties in Cairo, IL (CIR-Cairo Regional)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like near Cairo, IL (CIR-Cairo Regional)?

If you're flying into Cairo, IL (CIR-Cairo Regional), you might take some time to enjoy the sights in town. If you're looking for a convenient place to stay, you might search for properties close to public transportation so it's easy to get around.

Recent reviews of Cairo Regional hotels
Expedia verified reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

5/5 Excellent
"Great value and super quiet. "
A verified traveler stayed at Days Inn and Suites by Wyndham Sikeston
Posted 1 day ago
Days Inn and Suites by Wyndham Sikeston