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Top Cairo Regional Hotel Reviews

Drury Inn & Suites Sikeston, MO
10/10 Excellent
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Hotel options around Cairo Regional
- Welcoming 4-bedroom house with AC in charming La Center
- Drury Inn & Suites Sikeston, MO
- Fabulous cabin with AC in charming Tamms
- Beautiful Cabin Retreat
- Days Inn and Suites by Wyndham Sikeston
- The Riverview
- Country Yard Inn and Suite
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Super 8 by Wyndham Sikeston/Miner Area
- Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
- Comfort Inn & Suites Sikeston I-55
- Charming cottage overlooking Lake Acre
- Charming Home just minutes from Interstate and Mall
- Beautiful newly renovated farm house overlooking 5 acre lake. ****New Rates ***
- Courtyard by Marriott Cape Girardeau Downtown
- Holiday Inn Express & Suites Sikeston Southwest by IHG
- Hampton Inn Sikeston
- Quiet Country Stay: Modern Home Near Paducah
- Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.







