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Top Cairo Regional Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Oh my! The food was delicious, the bed is completely comfy, the room was clean and very nice, the drinks were perfect, all of the crowd that was there were all happy and pleased, I just can’t express how nice our stay was. In fact we’re staying again in the same place! ❤️"

Wandering the wineries or hitting the hills? We got you! Come stay!

10/10 Excellent

"Wonderful hosts with perfect communication all through the vist. Property is large enough for 4 couples, the gazebo with the firepit in the middle is perfect for fires in the other 3 seasons, was too hot to use it this time. Plenty of things to do, with a pool table, dartboard, board games. Yard is large and it's quiet other than road traffic. Decorated well in the hunting/fishing theme. Pets were welcome which is what we were after in trying to get away from an over abundance of fireworks in our area this year. Definitely worth checking out and bringing friends along with you."

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"I had a stay at this hotel. The rooms were clean, comfortable, and well maintained. The staff was friendly, professional, and always willing to help. The location was in a convenient place for us to take a quick rest The breakfast was delicious with plenty of options, and the overall atmosphere was relaxing and welcoming. I would definitely stay here again and highly recommend this hotel to anyone looking for a comfortable and enjoyable experience."

Welcoming 4-bedroom house with AC in charming La Center

10/10 Excellent

"We needed a 1 night stay, got in late. Great house and it was clean. The only comment I would say and they are very minor is, there was no light outside and it was very dark. Also, the rug at the front door both inside and out, had no grip so we slid around a bit."

Frequently asked questions

What's the area like near Cairo, IL (CIR-Cairo Regional)?

If you're flying into Cairo, IL (CIR-Cairo Regional), you might take some time to enjoy the sights in town. If you're looking for a convenient place to stay, you might search for properties close to public transportation so it's easy to get around.

What's the best place to stay near Cairo, IL (CIR-Cairo Regional)?

Quality Inn Cairo I-57 is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.1 mi (3.4 km) from Cairo, IL (CIR-Cairo Regional).

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Top Cairo Regional Hotel Reviews

Drury Inn & Suites Sikeston, MO

The Riverview

The Riverstone Hotel Charleston-Sikeston

Wandering the wineries or hitting the hills? We got you! Come stay!

Days Inn and Suites by Wyndham Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Welcoming 4-bedroom house with AC in charming La Center

Cozy cabins on beautiful Horseshoe Lake

Frequently asked questions

Explore a world of travel with Expedia

Hotel options around Cairo Regional

Find Hotels near Cairo Regional Airport (CIR)

Change your mind

Treat yourself

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Check prices for these dates

Filter by

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Top Cairo Regional Hotel Reviews

Drury Inn & Suites Sikeston, MO

Frequently asked questions

Explore a world of travel with Expedia

Hotel options around Cairo Regional