
Find Hotels near Cairo Regional Airport (CIR)
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for ${destinationAirportFriendlyName} hotels

Quality Inn Cairo I-57
Quality Inn Cairo I-573.4 km from Cairo, IL (CIR-Cairo Regional)
6.6 out of 10, (284 reviews)
The price is SAR 287
SAR 318 total
includes taxes & fees
12 May - 13 May

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO18 km from Cairo, IL (CIR-Cairo Regional)
6.8 out of 10, (630 reviews)
The price is SAR 236
SAR 262 total
includes taxes & fees
1 Jun - 2 Jun

Eagle Inn Charleston
Eagle Inn Charleston17.2 km from Cairo, IL (CIR-Cairo Regional)
6.6 out of 10, (106 reviews)
The price is SAR 206
SAR 229 total
includes taxes & fees
2 May - 3 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Cairo Regional Hotel Reviews

Drury Inn & Suites Sikeston, MO
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
Hotel options around Cairo Regional
- Drury Inn & Suites Sikeston, MO
- Fabulous cabin with AC in charming Tamms
- Beautiful Cabin Retreat
- Days Inn and Suites by Wyndham Sikeston
- ELEGANT COZY 3BR HOME
- The Riverview
- Super 8 by Wyndham Sikeston/Miner Area
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Country Yard Inn and Suite
- Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
- Comfort Inn & Suites Sikeston I-55
- Hampton Inn Sikeston
- Charming cottage overlooking Lake Acre
- Charming Home just minutes from Interstate and Mall
- Courtyard by Marriott Cape Girardeau Downtown
- Building at Cape Girardeau Regional Airport
- Quiet Country Stay: Modern Home Near Paducah
- Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
















