Find hotels in Cairo, IL from SAR 247

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Compare 22 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Quality Inn Cairo I-57

2.5 star property
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Housekeeping
6.6 out of 10, (259)
  • cleanliness
    Travelers start their day with a hearty breakfast before lounging by the pool or enjoying a quiet moment with coffee in the welcoming lobby area

What verified guests said

"Stay here almost weekly. Very quiet, not around anything other than a dollar general which is good. Just a bit pricey for a night. "

Quality Inn Cairo I-57 highlights

Quality Inn Cairo I-57 welcomes guests with a full breakfast and free in-room WiFi. Enjoy the seasonal outdoor pool and relax in the lobby with coffee, tea, and newspapers. The attentive front desk team is available around the clock.
The price is SAR 263
SAR 292 total
includes taxes & fees
19 Jul - 20 Jul
Quality Inn Cairo I-57

La Center Motel

2.0 star property
  • Parking included
  • Free WiFi
7.6 out of 10, Good, (13)

What verified guests said

"Clean, friendly, easy parking, good price, remodel restroom, good refrigerator and microwave "
La Center Motel

Eagle Inn Charleston

2.0 star property
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Gym
  • Housekeeping
6.8 out of 10, (100)
  • cleanliness
    Travelers find a quiet countryside escape with complimentary in-room WiFi at their fingertips and a health club ready for morning workouts

What verified guests said

"Comfortable bed, easy access to room"

Eagle Inn Charleston highlights

Eagle Inn Charleston offers a genuine rural retreat with free WiFi in rooms, access to health club facilities, complimentary self-parking, and 24/7 front desk staff.
The price is SAR 248
SAR 275 total
includes taxes & fees
25 Jun - 26 Jun
Eagle Inn Charleston

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Business services
6.6 out of 10, (567)
  • cleanliness
    Business travelers and late arrivals find convenience at this city-center motel where check-in is available around the clock

What verified guests said

"Gross"

Super 8 by Wyndham Charleston/Sikeston East MO highlights

Super 8 by Wyndham Charleston/Sikeston East MO is centrally located, offering a free to-go breakfast. Guests value the laundry services, reliable WiFi, business center, extended parking, and consistently praised staff.
The price is SAR 247
SAR 274 total
includes taxes & fees
29 Jun - 30 Jun
Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Charleston - Sikeston

2.5 star property
  • Breakfast included
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning
  • Business services
6.8 out of 10, (386)
  • cleanliness
    Travelers start their day with a hearty breakfast buffet at this welcoming hotel, where staying connected is easy no matter where they roam throughout the property

What verified guests said

"Very friendly and accommodating "

Quality Inn Charleston - Sikeston highlights

The Quality Inn Charleston - Sikeston offers a satisfying breakfast buffet and a practical business center. Guests appreciate the reliable WiFi, convenient RV/truck parking, and handy vending machine. Previous visitors consistently note the property's well-maintained condition.
The price is SAR 274
SAR 304 total
includes taxes & fees
13 Jul - 14 Jul
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Cairo

Escape to quaint Cairo! Enjoy its ruins, history, and riverfront.

Frequently asked questions

Where is the best place for a stay in Cairo?

Based on our traveler data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your trip to the area are Quality Inn Charleston - Sikeston and Super 8 by Wyndham Charleston/Sikeston East MO. See all available top hotels, or vacation rentals in Cairo.

What are some of the best vacation rentals in Cairo?

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286: This vacation home rental near Cairo is located in a rural location and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Cairo.

If I need to cancel my hotel reservation in Cairo, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.

Where can I learn more about changing or cancelling my trip to Cairo?

For more information about updating your trip to Cairo or cancelling it, head over to our customer service page.

Where is the best hotel to stay close to Fort Defiance?

Quality Inn Cairo I-57 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 4.9 mi (7.8 km) from Fort Defiance. Other good options around the area include Victorian Splendor in So. Illinois: wallmanor.com and Eagle Inn Charleston.

What's the best hotel for staying near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Cairo like?

Visitors can enjoy all that Cairo has to offer including the restaurants, entertainment choices, and riverfront. This city also attracts tourists with its small-town vibe. There are 22 hotels and other accommodations in the surrounding area. Find out more about Cairo.

What should I see while I'm in Cairo?

A couple of favorite places to visit are Mississippi River and Fort Defiance State Park. You'll also find Columbus-Belmont State Park and Ballard Wildlife Management Area in the area. Check out what more to see and do in Expedia's Cairo guide.

What's the seasonal weather like in Cairo?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.