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Find 4 Star Hotels in De Soto, MO

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Check availability on De Soto 4 Star Hotels

Compare De Soto 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

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Kayaking down the Big River on a fall day!
Photo by Jessica King
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Frequently asked questions

How much does it cost to stay in a 4-star hotel in De Soto?
To find a 4-star hotel in De Soto that's within your budget, make use of Expedia's handy filters. Check out the availability during your preferred dates and use our pricing filter to set your maximum rate. You can also sort your results by the most economical option first.

  • Search for the lowest price

What's the difference between 5-star and 4-star hotels in De Soto?
Treat yourself to luxury living during your De Soto escape by staying at a 4-star hotel. As well as featuring upscale accommodations, these retreats are typically filled with amenities, including large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. Round-the-clock concierge assistance, luxurious spas and gourmet dining are only the start of the first-rate conveniences and services you'll likely be able to enjoy.
Does De Soto have any 4-star all-inclusive resorts?
Finding your dream vacation in De Soto is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where almost everything is already taken care of like your meals, room, entertainment and activities, or choose a standard 4-star resort in or around this popular destination.