A shopping mall with a Magnolia Mall sign and a Burlington store across the street.

Cheap Flights from St. Louis (STL) to Florence (FLO)

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Popular airlines from St. Louis Lambert Intl. Airport (STL) to Florence, SC (FLO-Florence Regional)

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Frequently asked questions

Is it cheaper to buy a plane ticket from Lambert Field to Florence Regional Airport last minute?
Booking your trip from STL to Florence Regional Airport at the last minute could help you save if you're lucky to find a real bargain. However, tickets usually don't come down in price as the date of departure nears. If you choose to wait, flights could also be booked solid or the best seats taken. If you don't want to risk it, book well in advance of your departure date. Note that some of the biggest deals can be found up to a year in advance. If your preferred airline hasn't released its airfares yet, check back regularly as deals are updated on Expedia constantly.
What airports do you fly into for Florence from St. Louis?
Florence Regional Airport (FLO), Myrtle Beach Intl. Airport (MYR) and Hartsville Regional Airport (HVS) are your choices when traveling from St. Louis to Florence. About 3 kilometers east of central Florence, Florence Regional Airport (FLO) is the city's main entry point. Take into account factors like flight departure and arrival times and the distance to your hotel before settling on an airport. Magnolia Mall and Florence Museum are a couple of terrific attractions to visit when you arrive.
Can I change the date of my flight from STL to FLO?
It's so easy to make amendments to your Lambert Field to Florence Regional Airport journey yourself. Access your details via the Expedia Trips portal and choose "change flight." Look for new flights and secure the one that fits your new plans. You'll see an estimate of your flight change cost, if applicable. You can also find your way to our Customer Service portal to connect with our Virtual Agent and get answers to your questions.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Florence Regional
Distance
1070 km

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St. Louis to Florence Flights

Whether you’re looking for a grand adventure or just want to get away for a last-minute break, flights from St. Louis to Florence offer the perfect respite. Not only does exploring Florence provide the chance to make some magical memories, dip into delectable dishes, and tour the local landmarks, but the cheap airfare means you won’t bust your budget. So no matter whether your ideal itinerary involves flying one way, non-stop, or round trip, you’re bound to find flights that match your schedule on Expedia, and at prices that won’t shock your wallet.

Bagging a cheap flight from St. Louis to Florence may mean more dollars to spend on for one-of-a-kind souvenirs when you arrive, but it doesn’t mean you have to skimp on your travel experience, as Expedia offers a sizzling selection of cheap airlines that’ll put you in your happy place on their planes, whether that’s getting lost in a hair-raising airport thriller, dreaming on the passing landscape over a glass of bubbly, or jotting down your vacation bucket list at 38,000 feet. There’s also bound to be plenty of opportunities to snap a few photos of the high life that will make your friends green with envy. After all, enjoying the journey is part of the fun.

With so many affordable flights and so many wonderful adventures awaiting you, there’s no reason to put off booking a fantastic flight from to today. So don’t leave it to the last minute to make your dream trip a reality: pack your bags with your go-to travel accessories, put together your list of must-see attractions and can’t-miss activities, and get ready to broaden your horizons – with Expedia, the wonders of Florence are only a plane trip away. Book your travel arrangements with us today!

If you would like to book flights to Florence more flexibly many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Florence is now!

St. Louis to Florence Flights