Clayton, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's acclaimed art scene or attend a baseball game.
St. Louis Zoo
Why not visit the native and exotic animals who live at St. Louis Zoo during your trip to St. Louis? Amble around the area's lush forest or attend a sporting event.
City Museum
You can spend an afternoon studying the exhibits at City Museum during your trip to St. Louis. Experience the area's fascinating museums and great live music.
Forest Park
After visiting Forest Park, make a plan to see the other sights and activities in St. Louis. Discover the area's entertainment choices and shops.
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
Breakfast was fresh,
Reviewed on 12 January 2026
The Ritz-Carlton, St. Louis
Great property. Concierge level wonderful.
Reviewed on 2 January 2026
Le Méridien St. Louis Clayton
Nice
Reviewed on 5 January 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
We got upgraded which I thought was awesome but we had those Japanese Beatles in our room. They did offer to change to a smaller room so we just decided to flush them as we found them. Probably like 20-30 total. But for the warmer weather in St. Louis I guess that can be expected.
Reviewed on 7 January 2026
AC Hotel St. Louis Clayton
The room was very clean
Reviewed on 7 January 2026
Hyatt Regency St. Louis at The Arch
Room was clean, excellent view!
Reviewed on 13 January 2026
Other neighborhoods around Clayton
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Dogtown
If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.
Ladue
The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Art Museum, a few notable attractions nearby.
The Hill
If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Southwest Garden
Though Southwest Garden might not have many top sights, you can venture to the surrounding area to see attractions like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Clayton, MO
- Places of interest
- Clayton Hotels by Star Rating
- More Hotel Options in Clayton
- Hotels in top St. Louis neighborhoods
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- Chapel of St. Timothy And St. Titus
- St. Louis Union Station
- Busch Stadium
- Gateway Arch
- St. Louis Zoo
- Enterprise Center
- Washington University in St. Louis
- Barnes Jewish Hospital
- America's Center Convention Complex
- Dome at America’s Center
- City Museum
- Forest Park
- St. Louis University
- Ameristar Casino St. Charles
- Mississippi River
- Fox Theater
- Hollywood Casino Amphitheatre
- Horseshoe St. Louis Casino
- St Charles Convention Center
- Westport Plaza
- Anheuser-Busch Brewery
- Hidden Valley Ski Resort
- Magic House - St. Louis Children's Museum
- Route 66 State Park
- Show Me
- Missouri Botanical Gardens and Arboretum
- St. Louis Aquarium at Union Station
- Saint Louis Galleria Mall
- Grant's Farm
- Lindenwood University
- St. Louis Science Center
- Hollywood Casino
More Hotel Options in Clayton
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