4/5 - Good
Greg
I didn't spend any time in St. James. But for my brief stay, my impression is that it is safe and quiet.
Visit St. James
Greenlight Inn & Suites
110 N Outer Rd St. James MO
The price is SAR 219 per night from Jan 19 to Jan 20
SAR 219
SAR 249 total
19 Jan - 20 Jan
includes taxes & fees
Book a stay at this business-friendly hotel in St. James. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (448 reviews)
A very clean & comfortable place to stay. I really enjoyed my overnight stay and would return again, for sure.
Reviewed on 11 January 2026
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James
Saint James MO
The price is SAR 389 per night from Jan 20 to Jan 21
SAR 389
SAR 719 total
20 Jan - 21 Jan
includes taxes & fees
Stay at this vacation home in St. James. Enjoy laundry facilities, an in-room coffeemaker, and air conditioning. Popular attractions Rosati Winery Museum and ...
10/10 Exceptional! (25 reviews)
House is very clean and decorated really well!
Reviewed on 21 December 2025
Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.
Saint James MO
The price is SAR 375 per night from Jan 23 to Jan 24
SAR 375
SAR 675 total
23 Jan - 24 Jan
includes taxes & fees
Stay at this cottage in St. James. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions St. James Winery and Meramec Vineyards are ...
10/10 Exceptional! (52 reviews)
Easy to access, convenient location, quick reaponses from host and very cute property!
Reviewed on 23 December 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The James Stay on Historic Route 66, minutes away from Wineries & Restaurants
Saint James MO
Stay at this vacation home in St. James. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions St. James Winery and Meramec Vineyards ...
9.6/10 Exceptional! (29 reviews)
Nice house, very clean and close to everything. Enjoyed our stay.
Reviewed on 29 December 2025
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James
Saint James MO
Stay at this vacation home in St. James. Enjoy laundry facilities, an in-room coffeemaker, and air conditioning. Popular attractions Rosati Winery Museum and ...
10/10 Exceptional! (25 reviews)
House is very clean and decorated really well!
Reviewed on 21 December 2025
Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.
Saint James MO
Stay at this cottage in St. James. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions St. James Winery and Meramec Vineyards are ...
10/10 Exceptional! (52 reviews)
Easy to access, convenient location, quick reaponses from host and very cute property!
Reviewed on 23 December 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Maramec Spring Park
Explore the great outdoors at Maramec Spring Park, a lovely green space in St. James. While in this family-friendly area, you can enjoy the wineries.
St. James Winery
You can enjoy a tasting or tour at St. James Winery during your travels to St. James. While in this trendy area, you can enjoy the coffeehouses.
Rosati Winery Museum
You can spend an afternoon studying the exhibits at Rosati Winery Museum during your travels in St. James. While in this family-friendly area, you can enjoy the wineries.
Meramec Vineyards
You can enjoy a tasting or tour at Meramec Vineyards during your travels to St. James. While in this trendy area, you can enjoy the coffeehouses.
Great Circle
Though Great Circle might be what brings you to town, perhaps you'll have a chance to explore more of St. James while you are here.
Heinrichshaus Vineyard And Winery
You can enjoy a tasting or tour at Heinrichshaus Vineyard And Winery during your travels to St. James. While in this family-friendly area, you can enjoy the wineries.
Reviews of St. James
3.9
Guest rating
4/5 - Good
Verified traveler
I have traveled through this area several times in the past two years. There is an excellent winery right if the interstate!
5/5 - Excellent
Verified traveler
The people in St James were welcoming and social. The gentleman at O'Rielly's was SUPER knowledgeable and gave some great advice. It is just a lovely town and we look forward to our next visit.
4/5 - Good
Verified traveler
I lived here for years but it’s becoming a haven for pill heads(people who abuse pain medication). I’m aware that this problem has become nation wide but I had to move to a place nobody knew me.
3/5 - Okay
Verified traveler
Only there one night on trip from Arizona to Ohio
3/5 - Okay
Kris
Not a lot to do other than wine tasting on a Monday. I went to 3 that are open all week. Found a cool “junk shop” open on Tuesday—Casey’s. Paradise! I found two tools I had need of and a bunch of cool stuff I wanted, but didn’t have the trunk space.
- Maramec Spring Park
- St. James Winery
- Rosati Winery Museum
- Meramec Vineyards
- Heinrichshaus Vineyard And Winery
- Missouri University of Science and Technology
- Mark Twain National Forest
- The Fugitive Beach
- Meramec River
- Fanning Route 66 Outpost
- Lions Club Park
- Hood Park
- Onondaga Cave
- Cedar Street Playhouse
- Wenwood Farm Winery
- Peaceful Bend Vineyard
- Allgood-Bailey Stadium
- Fall Creek Rock Shop
