Find Business Hotels in St. James, MO

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on St. James Business Hotels

This weekend
Next weekend

Top St. James Business Hotels

Greenlight Inn & Suites

2.0 star property
St. James
8.6 out of 10, Excellent, (426)
"Very clean, comfortable bed, warm room very cozy after a long day traveling. Breakfast really good! I recommend this place!"
United States
Maria Victoria
The price is SAR 220
SAR 249 total
includes taxes & fees
1 Jan - 2 January 2026
Greenlight Inn & Suites

Escape to PARADISE on 10 sprawling acres in which to do anything you please!

Leasburg
9.8 out of 10, Exceptional, (33)
"We loved this place"
United States
Patricia B.
The price is SAR 1,010
SAR 1,366 total
includes taxes & fees
8 Dec - 9 Dec
Escape to PARADISE on 10 sprawling acres in which to do anything you please!

Spacious Ozarks Family Home - Private Pool & Grill

3.0 star property
Bourbon
The price is SAR 1,336
SAR 1,929 total
includes taxes & fees
5 Dec - 6 Dec
Spacious Ozarks Family Home - Private Pool & Grill

Days Inn & Suites by Wyndham Cuba

2.0 star property
Cuba
7.2 out of 10, Good, (757)
"Parking was secure, staff very friendly, rooms we’re excellent. "
United States
Kenneth
The price is SAR 270
SAR 307 total
includes taxes & fees
4 Jan - 5 January 2026
Days Inn & Suites by Wyndham Cuba

Super 8 by Wyndham Cuba

2.0 star property
Cuba
8.8 out of 10, Excellent, (985)
"Great place to stay if floating river."
United States
Denise
The price is SAR 297
SAR 337 total
includes taxes & fees
4 Jan - 5 January 2026
Super 8 by Wyndham Cuba

Hampton Inn Rolla

2.5 star property
Rolla
9.2 out of 10, Wonderful, (461)
"Staff friendly "
United States
Yanira
The price is SAR 375
SAR 426 total
includes taxes & fees
4 Jan - 5 January 2026
Hampton Inn Rolla

Rustic Motel Rolla

2.0 star property
Rolla
7.8 out of 10, Good, (243)
"Great rooms especially for the price. Super nice people too"
United States
Ruth
The price is SAR 237
SAR 267 total
includes taxes & fees
5 Dec - 6 Dec
Rustic Motel Rolla

Best Western Coachlight

2.5 star property
Rolla
7.6 out of 10, Good, (623)
"The staff was super friendly and the room was very clean"
United States
Jeremy
The price is SAR 338
SAR 380 total
includes taxes & fees
14 Dec - 15 Dec
Best Western Coachlight

Quality Inn Rolla

2.5 star property
Rolla
8.0 out of 10, Very Good, (359)
"Room was really clean, staff very friendly"
United States
Nadine
The price is SAR 281
SAR 324 total
includes taxes & fees
4 Jan - 5 January 2026
Quality Inn Rolla

Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG

2.5 star property
Rolla
8.8 out of 10, Excellent, (878)
"Clean, convenient and great breakfast buffet."
United States
Diana
The price is SAR 514
SAR 579 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. James Hotel Reviews

Explore a world of travel with Expedia