Photo by Ryan Coleman

Search Motels in Sikeston

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec
In one month
2 Jan - 4 Jan
In two months
30 Jan - 1 Feb

Motels in Sikeston

Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (611)
"Staff was great! Room was nice. "
United States
Lana
The price is SAR 220
SAR 244 total
includes taxes & fees
3 Dec - 4 Dec
Super 8 by Wyndham Charleston/Sikeston East MO
Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets
Town House Inn

Town House Inn

2.5 star property
Jackson
7.6 out of 10, Good, (422)
"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
The price is SAR 219
SAR 237 total
includes taxes & fees
1 Jan - 2 January 2026
Town House Inn
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

2.0 star property
Charleston
6.8 out of 10, (103)
"Middle of nowhere hotel was ok"
United States
David
The price is SAR 227
SAR 252 total
includes taxes & fees
3 Dec - 4 Dec
Eagle Inn Charleston
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite

Country Yard Inn and Suite

2.0 star property
Sikeston
6.8 out of 10, (117)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is SAR 200
SAR 239 total
includes taxes & fees
3 Dec - 4 Dec
Country Yard Inn and Suite
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Dexter

Econo Lodge Dexter

2.0 star property
Dexter
6.8 out of 10, (250)
"The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. "
United States
Michelle
The price is SAR 207
SAR 233 total
includes taxes & fees
31 Dec - 1 January 2026
Econo Lodge Dexter
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is SAR 263
SAR 307 total
includes taxes & fees
8 Dec - 9 Dec
Town House Inn Cape Giradreau
Exterior
OYO Hickory House Inn

OYO Hickory House Inn

2.5 star property
Dexter
5.4 out of 10, (128)
"Courteous staff"
United States
GEORGE
The price is SAR 164
SAR 207 total
includes taxes & fees
31 Dec - 1 January 2026
OYO Hickory House Inn
Exterior
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2.0 star property
Perryville
8.4 out of 10, Very Good, (935)
"The room was spotless, and the staff was extremely patient. Each one was very helpful. It was easy to get a good night's sleep - the building was very quiet."
United States
Cynthia
The price is SAR 249
SAR 285 total
includes taxes & fees
1 Jan - 2 January 2026
Super 8 by Wyndham Perryville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

White Friday Sale

Limited-time deals: Save up to 50% on select hotels
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Sikeston Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"I liked how comfortable the beds and pillows were."
Christine 4-night trip
Posted 2 days ago
Pear Tree Inn Cape Girardeau Near the Medical Center

Frequently asked questions

What can I expect from a motel trip to Sikeston?
If you can't find a motel in Sikeston, allow Expedia help you find motels or similar properties from over 35 lodging options in the area. Just use our search tools to filter by price per night or money-saving amenities such as free parking and free breakfast.
What are motels like?
At many motels, you'll often find an outdoor pool and a free parking spot. When you stay at a motel property, you'll usually access your room from an outside corridor overlooking the parking lot. In the U.S., motels became more commonplace at the end of the 1940s when cars became more popular along with road trip vacations, peaking in the mid-1960s with more than 60,000 properties.
What are the best motels in Sikeston?
These are some of Expedia customers' favorite motels to book in the larger area. Country Yard Inn and Suite: Enjoy access to the 24-hour front desk, and freebies including WiFi and parking. Super 8 by Wyndham Perryville: A 24-hour fitness center along with freebies like breakfast, WiFi, and parking are available during your stay. Central Sikeston is 59.7 mi (96.1 km) away. Town House Inn Cape Giradreau: Enjoy access to the 24-hour front desk, and freebies including WiFi and parking. Located 30.2 mi (48.6 km) from the heart of Sikeston. Super 8 by Wyndham Charleston/Sikeston East MO: Central Sikeston is 15 mi (24.1 km) away. A business center along with freebies like breakfast, WiFi, and parking are available during your stay. Town House Inn: 34.6 mi (55.7 km) from the heart of Sikeston. Enjoy access to the laundry facilities, and freebies including WiFi and parking.
What things can I to do in Sikeston?
In this family-friendly area, you can check out the shops and enjoy the restaurants while you're sightseeing. Those who've visited Sikeston like the riverfront. Parks and outdoorsy places nearby include Central Park and Hunter-Dawson State Historic Site. While you're checking out the area, consider visiting Sikeston Depot Museum, Front Street Studio & Art Gallery, and Stoddard County Civil War Memorial Cemetery.
What's the weather like in Sikeston?
Weather can make or break a roadtrip, so here's some data about year-round temperatures in Sikeston to help you plan yours: The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.
What are my options for getting around Sikeston when staying in a motel?
We've gathered some information about getting around Sikeston to help you navigate your stay: Fly into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the heart of the city. You can also search for flights into Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is 24.2 mi (38.9 km) away. If you'd like to venture out around the area, you may want a rental car for your journey.