Santuario Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to SAR 5,400 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santuario

Find the best Santuario areas and neighborhoods for the activities you enjoy most. Learn more about Santuario
The U.S. Airways Center with a large illuminated sign, surrounded by glass buildings and potted plants.

Downtown Phoenix

3 out of top 10 points of interest in this area

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Tom's Thumb Trail and Golf Club Scottsdale.

A building with a sign reading "MODE SALON + SPA" and a brick facade.

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Scottsdale Waterfront and Western Spirit: Scottsdale's Museum of the West.

A desert landscape with a large rock arch, a group of people climbing a hill, and distant mountains.

Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

An aerial view of a residential area with a lake, boats, and houses.

The Islands

While there might not be top attractions in The Islands, you can explore the larger area and discover places like Gilbert Civic Center and Gilbert Farmers Market.

Santuario Hotel Deals

Hilton Phoenix Tapatio Cliffs Resort

Hilton Phoenix Tapatio Cliffs Resort

11111 N 7th St Phoenix AZ
Fully refundableReserve now, pay when you stay
SAR 397
SAR 614 total
1 Sep - 2 Sep
includes taxes & fees
8.8/10 Excellent! (2,944 reviews)
"The room was very accommodating for the price but needs a little TLC to make it exceptional. The staff is fabulous; very personable, professional and helpful. There is a daily charge for parking, and it can be difficult to find a space near your room when the hotel is full. Luckily there are several ..."

Reviewed on 6 August 2026

Hilton Phoenix Tapatio Cliffs Resort
Talking Stick Resort

Talking Stick Resort

9800 E. Talking Stick Way Scottsdale AZ
Fully refundableReserve now, pay when you stay
SAR 448
SAR 618 total
20 Aug - 21 Aug
includes taxes & fees
Talking Stick Resort
Arizona Biltmore, LXR Hotels & Resorts

Arizona Biltmore, LXR Hotels & Resorts

2400 E Missouri Avenue Phoenix AZ
Fully refundableReserve now, pay when you stay
SAR 895
SAR 1,233 total
9 Aug - 10 Aug
includes taxes & fees
Arizona Biltmore, LXR Hotels & Resorts
See all 11,270 properties in Santuario
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.