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Check prices for these dates

Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec
In one month
2 Jan - 4 Jan
In two months
30 Jan - 1 Feb

Resorts in Santee

No exact matches found, but these alternatives could be just right

Recommended hotels in Santee

Lobby
Tru By Hilton Santee

Tru By Hilton Santee

2.5 star property
Santee
9.2 out of 10, Wonderful, (624)
"Nice place to stay"
Canada
Tanya
The price is SAR 357
SAR 397 total
includes taxes & fees
14 Dec - 15 Dec
Tru By Hilton Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1405)
"The best stay"
United States
Terez
The price is SAR 300
SAR 333 total
includes taxes & fees
30 Dec - 31 Dec
Baymont by Wyndham Santee
Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1001)
"Very welcoming, hotel has a clean and friendly presentation."
Canada
VALERIE AND JOHN
The price is SAR 454
SAR 504 total
includes taxes & fees
14 Dec - 15 Dec
Fairfield Inn & Suites by Marriott Santee
Seasonal outdoor pool
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 star property
Santee
9.6 out of 10, Exceptional, (1001)
"Breakfast was really good"
United States
Vinicius
The price is SAR 420
SAR 467 total
includes taxes & fees
10 Dec - 11 Dec
Hampton Inn Santee-I-95
Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is SAR 443
SAR 492 total
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Santee Inn
Exterior
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3.0 star property
Santee
8.2 out of 10, Very Good, (970)
"Was able to walk to convenience store and other dinning alternatives. Safe secure building"
United States
Joan
The price is SAR 417
SAR 463 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Santee by IHG
Lobby
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 star property
Santee
8.0 out of 10, Very Good, (1010)
"Close to the highway with a safe location."
United States
Benjamin
The price is SAR 370
SAR 411 total
includes taxes & fees
14 Dec - 15 Dec
Comfort Inn & Suites Santee
Exterior
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2.0 star property
Santee
7.0 out of 10, Good, (673)
"Breakfast could be a little better. Room was okay."
United States
Roger
The price is SAR 233
SAR 258 total
includes taxes & fees
28 Dec - 29 Dec
Travelodge by Wyndham Santee
Smart TV, offices
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee
10.0 out of 10, Exceptional, (37)
"Amazing host, comfy furniture, the fenced in yard was perfect for our fur babies! Hope to stay here again. 1.2 miles away from I-95! "
United States
Lauren B.
The price is SAR 378
SAR 1,228 total
includes taxes & fees
8 Dec - 9 Dec
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Smart TV, video games, books
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Santee
10.0 out of 10, Exceptional, (11)
"Nice place great location "
United States
Jeffrey H.
The price is SAR 724
SAR 1,729 total
includes taxes & fees
10 Dec - 11 Dec
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Lobby
Super 8 by Wyndham Santee

Super 8 by Wyndham Santee

2.0 star property
Santee
6.8 out of 10, (438)
"Clean room and felt safe and secured. "
United States
Kelly
The price is SAR 281
SAR 312 total
includes taxes & fees
8 Dec - 9 Dec
Super 8 by Wyndham Santee
Lobby
Red Roof Inn Santee

Red Roof Inn Santee

2.0 star property
Santee
6.6 out of 10, (637)
"It's a good stop for the price "
United States
Martin
The price is SAR 263
SAR 292 total
includes taxes & fees
8 Dec - 9 Dec
Red Roof Inn Santee
Business center
Quality Inn & Suites

Quality Inn & Suites

2.5 star property
Santee
6.0 out of 10, (452)
"Great place. Excellent people. Great service"
United States
Jesse
The price is SAR 204
SAR 247 total
includes taxes & fees
18 Dec - 19 Dec
Quality Inn & Suites
Exterior
Econo Lodge

Econo Lodge

2.0 star property
Santee
6.4 out of 10, (309)
"Check in was easy."
United States
Amy
The price is SAR 235
SAR 261 total
includes taxes & fees
24 Dec - 25 Dec
Econo Lodge
Property amenity
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2.0 star property
Santee
6.2 out of 10, (541)
"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
The price is SAR 292
SAR 325 total
includes taxes & fees
21 Dec - 22 Dec
Ramada by Wyndham Santee I-95
Lobby
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1001)
"Staff are great, room is clean and amenities very amusing "
United States
Salah
The price is SAR 387
SAR 430 total
includes taxes & fees
4 Jan - 5 January 2026
Tru by Hilton Orangeburg
Exterior
Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG

2.5 star property
Orangeburg
8.6 out of 10, Excellent, (793)
"The room was spotless and the staff was courteous. "
United States
Terrance
The price is SAR 357
SAR 397 total
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Express & Suites Orangeburg by IHG
Reception
Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg

2.5 star property
Orangeburg
8.4 out of 10, Very Good, (684)
"Enjoyed my stay for homecoming go Bulldogs ! "
United States
David
The price is SAR 315
SAR 350 total
includes taxes & fees
4 Jan - 5 January 2026
Fairfield Inn by Marriott Orangeburg
Exterior
Best Inn of Manning

Best Inn of Manning

2.5 star property
Manning
7.4 out of 10, Good, (6)
"I was not pleased that I called after making reservation to request a room on the main level and was told that they would make a note and that this would be arranged but when I got there, they had me in an upstairs room. When I discussed this with the young lady at the front desk, she was kind and accomodating but I was put in a room then switched to another room. The bath tub faucet came out of the wall when I tried to pull up the tub plug. There was no waste basket in the room and the floor...
United States
rhonda
The price is SAR 272
SAR 302 total
includes taxes & fees
7 Dec - 8 Dec
Best Inn of Manning
Front of property
Peach Tree Inn

Peach Tree Inn

2.5 star property
St. George
7.2 out of 10, Good, (133)
"Air conditioning very good, check in easy, staff very pleasant"
United States
Linda
Peach Tree Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10/10 Excellent
"This home was perfect for our Thanksgiving family getaway. We really enjoyed everything about the house, especially the fenced yard for the dogs. I would definitely stay here again. The house was exceptionally clean. "
Kelly C. 3-night trip
Posted 3 days ago
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Frequently asked questions

What can I expect from a resort vacation in Santee?
Longing for a relaxing escape? Indulge in the comforts of a resort, where you can find everything you want for your vacation from tasty food and drink options to activities and entertainment. Pick from 7 resorts in Santee and discover the best one for you, whether you envision yourself sitting down to fine dining or heading to the spa for a deep-tissue massage.
What's a favorite resort in Santee?
Waterfront Condo on Lake Marion - Golf resort. Features a fitness center. Lake Marion 2Bed/2Bath Deluxe! - Enjoy the fitness center, garden, and outdoor pool. Lake Marion 3Bed/3Bath Deluxe! - Amenities include a fitness center, a garden, and an outdoor pool. 2Bed/2Bath Deluxe at Lake Marion! - Access to a fitness center, a garden, and an outdoor pool.
How many resorts will I find in Santee?
Choose among Expedia's 7 resort hotels in Santee where you'll find onsite spas, beautiful rooms, and more.
What can I do in Santee?
Travelers enjoy the golfing and other activities in Santee, and also have good things to say about the dining options here. If you brought your golf clubs, you can hit the links at Santee Cooper Country Club or Santee National Golf Club. Additional attractions in the area include Santee State Park and Lake Marion.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's the best way to get to and around Santee?
Fly into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the heart of the city. If you'd like to venture out around the area, you may want to rent a car for your trip.