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Check prices for these dates

Next weekend
19 Dec - 21 Dec
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26 Dec - 28 Dec
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9 Jan - 11 Jan
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6 Feb - 8 Feb

Our top choices for Santa Fe Depot vacation homes

Dining
Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown

Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown

Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown
Central Oklahoma City
10.0 out of 10, Exceptional, (118)
"We needed a place to stay while our home went through some repairs and while our oldest son receives treatment at Oklahoma City Children's Hospital for a rare cancer. This place was close, clean and affordable for our entire family!"
United States
Christina P.
Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown
Property grounds
Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!

Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!

Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!
Central Oklahoma City
9.8 out of 10, Exceptional, (39)
"Great place, location, and communication! Would definitely recommend to others and would book again. "
United States
Amanda S.
Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!
Fridge, microwave, oven, stovetop
Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly

Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly

Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly
Central Oklahoma City
9.2 out of 10, Wonderful, (19)
"The kitchen was well equipped, property was clean, and just what we need for our two small dogs."
United States
Casey H.
The price is SAR 919
SAR 1,961 total
includes taxes & fees
18 Dec - 19 Dec
Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly
Fridge, microwave, oven, stovetop
Cozy 2-bedroom, 2-bath house in charming Oklahoma City

Cozy 2-bedroom, 2-bath house in charming Oklahoma City

Cozy 2-bedroom, 2-bath house in charming Oklahoma City
Central Oklahoma City
10.0 out of 10, Exceptional, (1)
"We thoroughly enjoyed our stay in this very clean and nicely done bungalow. It was centrally located to all we had planned. It was quiet and comfortable, with good AC, ceiling fans and comfortable furnishings. The listing was missing a few things I found on another site but I have seen that with VRBO before and do not fault the owner. The owner was extremely responsive to all queries, even late at night. Overall, it was a very good stay and we will definitely stay again when we return for...
United States
Eileen K.
Cozy 2-bedroom, 2-bath house in charming Oklahoma City
TV, fireplace
Beautiful 4 Bed House With King Bed & HOA Park

Beautiful 4 Bed House With King Bed & HOA Park

Beautiful 4 Bed House With King Bed & HOA Park
Central Oklahoma City
9.2 out of 10, Wonderful, (12)
"Very convenient to the OUHSC. Close access to midtown and downtown as well. Good communication with the hosts and having a garage was a nice bonus. "
United States
Kendra H.
Beautiful 4 Bed House With King Bed & HOA Park
Fridge, microwave, oven, stovetop
Spacious 4 Bed House With King Bed & Playground

Spacious 4 Bed House With King Bed & Playground

Spacious 4 Bed House With King Bed & Playground
Central Oklahoma City
9.6 out of 10, Exceptional, (11)
"Great property, clean, comfy beds...everything we needed...and the communication was excellent!"
United States
Katrina P.
The price is SAR 553
SAR 1,169 total
includes taxes & fees
15 Dec - 16 Dec
Spacious 4 Bed House With King Bed & Playground
Exterior
Midtown Historic Bungalow

Midtown Historic Bungalow

Midtown Historic Bungalow
2.0 star property
Central Oklahoma City
10.0 out of 10, Exceptional, (4)
"We loved our weekend stay at this cute little house!"
United States
Meghan K.
Midtown Historic Bungalow
Fridge, microwave, oven, stovetop
Beautifully Remodeled 3B1.5B W/ King Bed By OU Med

Beautifully Remodeled 3B1.5B W/ King Bed By OU Med

Beautifully Remodeled 3B1.5B W/ King Bed By OU Med
Central Oklahoma City
9.4 out of 10, Exceptional, (11)
"Great stay! Very very good communication with host!"
United States
Mike S.
Beautifully Remodeled 3B1.5B W/ King Bed By OU Med
Interior
Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking

Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking

Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking
Central Oklahoma City
10.0 out of 10, Exceptional, (7)
"It was a good overall experience for a family with kids to stay in this property. Thanks Colten!!!"
United States
sugumar r.
Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking
Interior
"The Ivyson" on 10th Urban Core Midtown OKC

"The Ivyson" on 10th Urban Core Midtown OKC

"The Ivyson" on 10th Urban Core Midtown OKC
Central Oklahoma City
6.0 out of 10, (1)
"The place looked just like the pictures. Nicely decorated and very clean. The downstairs bed is bigger than it looks in the picture. My two teen girls slept in it just fine. My only complaint is it smelled like someone had smoked weed in the house. It gave two of us really bad headaches and one of my kids got sick to her stomach from it. Overall we loved the place…except the weed smell! "
United States
Julie N.
"The Ivyson" on 10th Urban Core Midtown OKC
Fridge, microwave, oven, stovetop
Quiet 4 Bed Home With HOA Park

Quiet 4 Bed Home With HOA Park

Quiet 4 Bed Home With HOA Park
Central Oklahoma City
8.8 out of 10, Excellent, (5)
"This VRBO was clean and quiet. Cute space "
United States
Kristen M.
Quiet 4 Bed Home With HOA Park
Fridge, microwave, oven, stovetop
Modern OKC Retreat: Half-Mile to Plaza District!

Modern OKC Retreat: Half-Mile to Plaza District!

Modern OKC Retreat: Half-Mile to Plaza District!
Central Oklahoma City
10.0 out of 10, Exceptional, (4)
"We had great communication from our host. We found the house stocked with everything we needed."
United States
Nancy W.
Modern OKC Retreat: Half-Mile to Plaza District!
Private kitchen
Velvet studio apartment located in Deep Duece.

Velvet studio apartment located in Deep Duece.

Velvet studio apartment located in Deep Duece.
2.0 star property
Downtown Oklahoma City
9.6 out of 10, Exceptional, (10)
"Great location and very cute apartment"
United States
DUSTYN ROSE
Velvet studio apartment located in Deep Duece.
Fridge, microwave, oven, stovetop
Howes Capitol–3 in 1-near OU Med, Bricktown, Arena

Howes Capitol–3 in 1-near OU Med, Bricktown, Arena

Howes Capitol–3 in 1-near OU Med, Bricktown, Arena
Central Oklahoma City
9.2 out of 10, Wonderful, (7)
"Recommend this listing for families who would like the 3 seperate duplexes / apartments all next to each other (would not recommend for an individual family that does not want to sleep separately from kids, etc). All 3 were extremely comfortable and spacious, next to each other and right in the heart of Oklahoma City."
Australia
Gabbi L.
Howes Capitol–3 in 1-near OU Med, Bricktown, Arena
Exterior
Blue Bungalow near OU Med/Downtown 0 cleaning fee

Blue Bungalow near OU Med/Downtown 0 cleaning fee

Blue Bungalow near OU Med/Downtown 0 cleaning fee
Central Oklahoma City
8.8 out of 10, Excellent, (9)
"I would recommend this stay to whomever has business or visiting family. House was just as described as in the site. It close to Oklahoma University. If you up for a bit of nostalgia, they have an old Airsteam you can sleep in. I was extremely impressed with this home. Would recommend. "
United States
Kenneth V.
Blue Bungalow near OU Med/Downtown 0 cleaning fee
TV, offices
Entire Lincoln Lodge by OU Medical

Entire Lincoln Lodge by OU Medical

Entire Lincoln Lodge by OU Medical
Central Oklahoma City
9.6 out of 10, Exceptional, (14)
"Love the property! Very clean, nicely decorated, quiet neighborhood. All the basics were supplied and everything was very very comfortable, but don’t look for luxury bedding if that’s your thing. Tons of space for everyone. Huge bonus: you don’t have to spend the morning of checkout stripping beds, mopping floors, cleaning bathrooms, etc. They do all that!!! Amazing and made things stress free. Would definitely stay again! "
United States
J L.
Entire Lincoln Lodge by OU Medical
Fridge, microwave, oven, stovetop
Casa Rivera Uptown with 2 king beds

Casa Rivera Uptown with 2 king beds

Casa Rivera Uptown with 2 king beds
Central Oklahoma City
Casa Rivera Uptown with 2 king beds
Outdoor dining
Upscale living in Downtown OKC. Unbeatable location and pet friendly!

Upscale living in Downtown OKC. Unbeatable location and pet friendly!

Upscale living in Downtown OKC. Unbeatable location and pet friendly!
Downtown Oklahoma City
2.0 out of 10, (1)
"Got confirmation at booking and 48 hours prior to check in. Then no door code, 3 hours before anyone could get ahold of owner who had no knowledge of booking. I had to get another room. "
United States
Dan D.
Upscale living in Downtown OKC. Unbeatable location and pet friendly!
Exterior detail
Chic 50s Time Capsule Downtown/OU Med/OK Capitol

Chic 50s Time Capsule Downtown/OU Med/OK Capitol

Chic 50s Time Capsule Downtown/OU Med/OK Capitol
Central Oklahoma City
9.8 out of 10, Exceptional, (11)
"Fun place to stay!"
United States
Christina F.
Chic 50s Time Capsule Downtown/OU Med/OK Capitol
Living area
Brick View Studio in downtown Oklahoma City

Brick View Studio in downtown Oklahoma City

Brick View Studio in downtown Oklahoma City
2.0 star property
Downtown Oklahoma City
Brick View Studio in downtown Oklahoma City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Fe Depot Hotel Reviews

Hyatt Place Oklahoma City / Bricktown

Hyatt Place Oklahoma City / Bricktown

10/10 Excellent
"Safe and clean stay "
Marc 1-night trip
Posted 11 hours ago
Hyatt Place Oklahoma City / Bricktown