Medical Center District, TX

San Antonio

Photo by Linda Cronan

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Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is SAR 333 per night from Dec 7 to Dec 8
SAR 333
SAR 394 total
7 Dec - 8 Dec
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,098 reviews)
Very clean and comfortable room.

Reviewed on 5 December 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is SAR 334 per night from Dec 7 to Dec 8
SAR 334
SAR 397 total
7 Dec - 8 Dec
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (1,031 reviews)
The room is clean and the hotel staff are all nice including the staff from the restourant

Reviewed on 30 November 2025

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is SAR 334 per night from Dec 19 to Dec 20
SAR 334
SAR 395 total
19 Dec - 20 Dec
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,007 reviews)
Room was clean, staff was very friendly!!

Reviewed on 19 November 2025

Courtyard by Marriott Medical Center San Antonio
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is SAR 389 per night from Dec 7 to Dec 8
SAR 389
SAR 567 total
7 Dec - 8 Dec
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (2,202 reviews)
Perfect location!

Reviewed on 3 December 2025

Hotel Valencia Riverwalk
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,156 reviews)
This is a historic building. We arrived early and the staff gave us zero grief about holding our bags until it was time to check in. We also checked out and wanted to explore before we caught our plane home. Once again… zero grief. The rooms are in need of some minor repairs and paint touch ups. ...

Reviewed on 30 November 2025

Riverwalk Plaza
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street San Antonio TX
The price is SAR 267 per night from Dec 14 to Dec 15
SAR 267
SAR 381 total
14 Dec - 15 Dec
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (3,782 reviews)
Loved it, clean nice just a walk away to riverwalk

Reviewed on 2 December 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Medical Center District

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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Northwest Side
Brackenridge Park

Midtown

3.5/5(197 area reviews)

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like San Antonio Museum of Art and Historic Brackenridge Golf Course.

Tobin Hill
Marion Koogler McNay Art Museum featuring art and interior views

Uptown

While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Uptown
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Alamo Heights

You'll enjoy the museums and coffeehouses in Alamo Heights. You might want to make time for a stop at San Antonio River or Harry B Orem Stadium.

Alamo Heights


Medical Center District, TX

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