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Check prices for these dates

Tonight
11 May - 12 May
Tomorrow
12 May - 13 May
This weekend
15 May - 17 May
Next weekend
22 May - 24 May

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Our top choices for O Brien hotels

Individually decorated, desk, laptop workspace, iron/ironing board

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,001 reviews)
"Low cost but worth it"
United States
Michael
The price is SAR 225
SAR 253 total
includes taxes & fees
12 May - 13 May
Days Inn by Wyndham Lake City I-10
Premium bedding, desk, blackout drapes, soundproofing

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (606 reviews)
"Staff nice and helpful"
United States
Drew
The price is SAR 244
SAR 274 total
includes taxes & fees
12 May - 13 May
Palms Garden Inn
Lobby sitting area

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
7.8 out of 10, Good, (166 reviews)
"Staff was very nice"
United States
Susan
The price is SAR 274
SAR 308 total
includes taxes & fees
12 May - 13 May
Motel 6 – Lake City, Fl – Medical Center
Down comforters, pillowtop beds, blackout drapes, free WiFi

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (709 reviews)
"Great counters in the bathroom!! Loved the served breakfast and dinner!"
United States
Wendy
The price is SAR 236
SAR 265 total
includes taxes & fees
10 Jun - 11 Jun
Super 8 by Wyndham Lake City
Exterior

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,011 reviews)
"Great stay, nice area"
United States
Jennifer
The price is SAR 390
SAR 439 total
includes taxes & fees
31 May - 1 Jun
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
BBQ/picnic area

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,022 reviews)
"Staff , AC very good, clean"
United States
John C
The price is SAR 252
SAR 283 total
includes taxes & fees
12 May - 13 May
Americas Best Value Inn Lake City
Reception

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (185 reviews)
"The parking was easy, and it’s a beautiful place. We really liked the history and decor, and the common spaces were a plus!"
United States
LEYA
The price is SAR 507
SAR 570 total
includes taxes & fees
28 May - 29 May
The Blanche
Indoor pool

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (234 reviews)
"Excellent stay. Great breakfast. "
United States
Janet
The price is SAR 522
SAR 587 total
includes taxes & fees
18 May - 19 May
Fairfield Inn & Suites Lake City
Exterior

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (207 reviews)
"Very happy to have stayed here. Great place, clean well designed, pretty and with all the amenities ready to use and working. Im glad I choose this place and highly recommend it."
United States
Andy
The price is SAR 559
SAR 945 total
includes taxes & fees
14 May - 15 May
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Suite, Multiple Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, iron/ironing board

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,010 reviews)
"The staff was very nice, breakfast was good and they kept a watch on to replace any items that needed. The room was clean, the beds comfortable. We had a wonderful stay."
United States
Evelin
The price is SAR 432
SAR 486 total
includes taxes & fees
25 May - 26 May
Comfort Suites Lake City
Breakfast area

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (510 reviews)
"Room was very clean, breakfast was awesome, everything was good."
United States
James
The price is SAR 390
SAR 439 total
includes taxes & fees
17 May - 18 May
Hampton Inn & Suites Alachua I-75
Lobby

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,062 reviews)
"Breakfast was very good."
United States
Bradley
The price is SAR 390
SAR 439 total
includes taxes & fees
31 May - 1 Jun
Best Western Plus Lake City
Pillowtop beds, in-room safe, desk, blackout drapes

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,006 reviews)
"Good hotel for the price."
United States
John
The price is SAR 237
SAR 267 total
includes taxes & fees
12 May - 13 May
Days Inn by Wyndham Lake City I-75
Exterior

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (250 reviews)
"Clean hotel, nice room, good value."
United States
Danielle
The price is SAR 411
SAR 463 total
includes taxes & fees
24 May - 25 May
Courtyard By Marriott Lake City
1 bedroom, laptop workspace, free WiFi, bed sheets

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (18 reviews)
"Calm peaceful stay, staff was very helpful and attentive. "
United States
Patrick
The price is SAR 363
SAR 654 total
includes taxes & fees
13 May - 14 May
Vista Verde Farm Retreat
Exterior

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,106 reviews)
"Overall a nice stay"
United States
Crystal
The price is SAR 392
SAR 441 total
includes taxes & fees
24 May - 25 May
La Quinta Inn & Suite by Wyndham Lake City
Lobby

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (668 reviews)
"It's a great place to stay if you're going to a festival at the spirit of Suwanee music Park "
United States
Elizabeth
The price is SAR 269
SAR 296 total
includes taxes & fees
2 Jun - 3 Jun
Quality Inn White Springs Suwanee
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,002 reviews)
"Breakfast menu was fresh, the room was clean, and the staff friendly and professional."
United States
Claire
The price is SAR 540
SAR 608 total
includes taxes & fees
17 May - 18 May
Hampton Inn & Suites Lake City
Snack bar

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,010 reviews)
"Very clean and a great place to stay!"
United States
Charika
The price is SAR 409
SAR 460 total
includes taxes & fees
31 May - 1 Jun
Tru by Hilton Lake City
Fountain

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (439 reviews)
"Wonderful staff nice location clean rooms"
United States
Wayne
The price is SAR 355
SAR 399 total
includes taxes & fees
13 May - 14 May
BlueGem Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Best Western Plus Lake City

Best Western Plus Lake City

10/10 Excellent
"Quiet Clean &comfortable"
William 1-night trip
Posted 2 hours ago
Best Western Plus Lake City

More cheap stays in O Brien

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

3835 West US Highway 90 Lake City FL
The price is SAR 252 per night from May 12 to May 13
SAR 252
SAR 283 total
12 May - 13 May
includes taxes & fees
8.6/10 Excellent! (1,022 reviews)

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Comfort Suites Lake City. See all available top hotels, or vacation rentals in O Brien.
What's the top vacation rental in O Brien?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Provides on-the-go, an indoor pool, and free self parking. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and Little River Spring Cave divers poolside Hideaway are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Bob's River Place in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.