Matthews Vacations

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    Save up to SARĀ 5,400 when you book a flight and hotel together*

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Find the Best Matthews Vacation Packages

Matthews Hotel Deals

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is SARĀ 417 per night from Jul 21 to Jul 22
SARĀ 417
SARĀ 479 total
21 Jul - 22 Jul
includes taxes & fees
Drury Inn & Suites Sikeston, MO
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is SARĀ 338 per night from Aug 9 to Aug 10
SARĀ 338
SARĀ 386 total
9 Aug - 10 Aug
includes taxes & fees
Best Western Plus Sikeston I-55
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
The price is SARĀ 252 per night from Aug 9 to Aug 10
SARĀ 252
SARĀ 287 total
9 Aug - 10 Aug
includes taxes & fees
7.2/10 Good! (1,000 reviews)
"I had a stay at this hotel. The rooms were clean, comfortable, and well maintained. The staff was friendly, professional, and always willing to help. The location was in a convenient place for us to take a quick rest The breakfast was delicious with plenty of options, and the overall atmosphere was ..."

Reviewed on 4 July 2026

Days Inn and Suites by Wyndham Sikeston
See all 45 properties in Matthews
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matthews vacation package cost?
You can pick up a vacation package to this popular destination on Expedia. But how much your vacation to Matthews costs will depend on the season, length of stay and hotel choice.
What are the cheapest months to go to Matthews?
If you're looking to book a cheap Matthews vacation package, consider visiting in January, February and November. You're likely to find lower rates on hotels and airfares during these months ā€” ideal for a budget-friendly getaway.
How to find the best Matthews package deals?
Finding a cheap Matthews package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your maximum budget, apply a few filters and see what's available. You can fine-tune your search by "Amenities," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most affordable Matthews package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book a Matthews vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalized Matthews vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Matthews?
If you're planning a spontaneous Matthews adventure, check out our last-minute deals that can be booked up to one week before you go. Don't want to leave things to the last minute? You can find amazing deals on your hotels and flights by booking well in advance.
How to plan a trip to Matthews?

  1. Choose when to travel: Check your schedule and get packing. Your preferred season and the activities on offer will also help you decide when to vacation in Matthews.
  2. Plan your budget wisely: In addition to the price of your stay, you should factor in other expenses too. These include flights, food and transportation. Also, put aside a little extra for unexpected expenses that could crop up during your trip to Matthews.
  3. Decide how many days away: Start by compiling a list of the activities and attractions you'd like to experience in Matthews. Then, estimate how long you'll need for each, along with any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a personalized Matthews vacation package.