Matlacha Isles Vacations
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Where to stay in Matlacha Isles
Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles
Pelican
1 out of top 10 points of interest in this area
If you're spending some time in Pelican, Tarpon Point and Rotary Park Environmental Center are top sights worth seeing.
Matlacha Isles Hotel Deals
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is SARĀ 714 per night from Aug 17 to Aug 18
SARĀ 714
SARĀ 984 total
17 Aug - 18 Aug
includes taxes & fees
9/10 Wonderful! (2,330 reviews)
"Love love love it. ."
Reviewed on 17 July 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is SARĀ 718 per night from Aug 10 to Aug 11
SARĀ 718
SARĀ 932 total
10 Aug - 11 Aug
includes taxes & fees
8.6/10 Excellent! (1,002 reviews)
"Hotel was pretty the yacht wasnāt running the lobby stuff was rude unknown charges at check in 600 plus no beach access big disappointment had to pay parking an toll fees to go to a beach told them we were there to celebrate my husbands birthday they done nothing special to help us celebrate just ..."
Reviewed on 16 July 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is SARĀ 558 per night from Aug 16 to Aug 17
SARĀ 558
SARĀ 706 total
16 Aug - 17 Aug
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.