A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Resorts & Hotels with Spas in Key Largo, FL

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Check availability on Key Largo Resorts & Hotels with Spas

Tonight
2 Oct - 3 Oct
Tomorrow
3 Oct - 4 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Key Largo hotels with a spa

A hotel room with a bed, a dresser, a mirror, and a nightstand.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A beachfront property with a balcony overlooking the sea, palm trees, and a well-lit outdoor seating area.
A poolside area with blue chairs and a thatched-roof structure.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
  • Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
SAR 822
SAR 1,075 total
includes taxes & fees
4 Oct - 5 Oct
Reefhouse Resort & Marina
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.
A beachside patio with lounge chairs, a table, and a view of the ocean.
An aerial view of a resort with a large pool, palm trees, and a beach.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.

2. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
SAR 987
SAR 1,318 total
includes taxes & fees
19 Oct - 20 Oct
Playa Largo Resort & Spa, Autograph Collection
A view through a window with metal bars, featuring a beach with palm trees, a thatched umbrella, and a wooden dock.
A tropical resort with a paved pathway leading to a building, surrounded by palm trees and lush greenery.
A beachside resort with lounge chairs, a pool, and palm trees.
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a sign indicating no diving.

3. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
  • Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
SAR 603
SAR 784 total
includes taxes & fees
4 Oct - 5 Oct
Kona Kai Resort and Gallery - Adults Only
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A balcony with white wicker furniture, a table with a drink and snacks, and a view of the ocean.
A living room with a view of turquoise waters, a white sofa, a glass coffee table, and a wicker chair.
A coconut drink with a straw, a cherry, and a slice of fruit on a table by a pool with a waterfall and palm trees in the background.

4. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
SAR 1,044
SAR 1,381 total
includes taxes & fees
12 Oct - 13 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A wooden table with two white cups, one with coffee and one with tea, placed on a body of water.
A floating house with a thatched roof, large sliding glass doors, and a wooden deck with a chair.
A floating house with a thatched roof, a glass door, and a small deck area.
A couple in a room with a large window overlooking the sea, a bed with pillows, a small table with a vase of flowers, and a plant.

5. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
Key Largo
  • Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
SAR 2,662
SAR 2,995 total
includes taxes & fees
11 Oct - 12 Oct
Premium Floating Bungalow by Stay Ombi
A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A balcony with a view of palm trees and the sea, a white railing, and a table with chairs.
A tropical resort with a swimming pool, palm trees, and a waterfall.

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
SAR 492
SAR 828 total
includes taxes & fees
4 Oct - 5 Oct
Cheeca Lodge & Spa
A hotel room with two beds, a large window with a view of a balcony, and a curtain on the window.
A balcony with two wooden chairs and a small table, overlooking a beach with palm trees and the ocean.
A modern hotel room with a balcony, a flat-screen TV, a sofa, a dining table, and a view of the ocean.
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.

7. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
  • Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
SAR 1,842
SAR 2,316 total
includes taxes & fees
7 Oct - 8 Oct
The Islands of Islamorada
View all properties

Choose what matters most at spa hotels in Key Largo

Pool
Hot tub
Breakfast included
Gym
5 stars

Top Key Largo Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"Great amenities and activities for a family with yound children. Two very different beach area atmospheres made for a nice variety of experiences."
Austin 4-night trip
Posted 11 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Dove Creek Resort & Marina, Trademark Collection by Wyndham

Dove Creek Resort & Marina, Trademark Collection by Wyndham

10/10 Excellent
"We have a really good time"
Raquel 3-night trip
Posted 1 day ago
Dove Creek Resort & Marina, Trademark Collection by Wyndham
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Nice property. Disappointed we could not check in earlier."
Marcus B. 2-night trip
Posted 2 days ago
Reefhouse Resort & Marina
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

8/10 Good
"Decent hotel to stay at. Breakfast was pricey, we searched elsewhere to eat. We couldn’t connect to the WiFi in the room the whole week. Their tech tried to help, but no luck. Close to restaurants and sites that we wanted to go visit."
Ann 5-night trip
Posted 2 weeks ago
Holiday Inn Key Largo by IHG

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 4 restaurants, 3 bars, a 24-hour fitness center, and a hair salon. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia's 1296 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a bit of extra time while you're in the area, you might want to check out John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.