Irene Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to SARĀ 5,400 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Irene Vacation Packages

Irene Hotel Deals

Best Western Kelly Inn

Best Western Kelly Inn

2.5 out of 5
1607 E Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
The price is SARĀ 425 per night from Jul 19 to Jul 20
SARĀ 425
SARĀ 470 total
19 Jul - 20 Jul
includes taxes & fees
Best Western Kelly Inn
Comfort Inn Yankton SD

Comfort Inn Yankton SD

2.5 out of 5
611 W 23rd Street Yankton SD
Fully refundable
The price is SARĀ 425 per night from Aug 9 to Aug 10
SARĀ 425
SARĀ 470 total
9 Aug - 10 Aug
includes taxes & fees
8.8/10 Excellent! (746 reviews)
"Thank you for the giant carafe of ice cold lemon water. That made my day."

Reviewed on 13 July 2026

Comfort Inn Yankton SD
Econo Lodge Inn & Suites Yankton

Econo Lodge Inn & Suites Yankton

2 out of 5
2410 Broadway Ave Yankton SD
Fully refundable
The price is SARĀ 351 per night from Aug 11 to Aug 12
SARĀ 351
SARĀ 389 total
11 Aug - 12 Aug
includes taxes & fees
Econo Lodge Inn & Suites Yankton
See all 86 properties in Irene
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Irene vacation package cost?
You can snap up a vacation package to this destination on Expedia. However, how much your vacation to Irene costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Irene?
You can typically find lower rates and greater availability in January, February and November. Explore our cheap Irene vacation packages and you could get some excellent off-season deals.
How to find the best Irene package deals?
Bagging a cheap Irene package deal is easy with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your maximum budget, apply a few filters and see what's available. You can customize your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most economical Irene package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book an Irene vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll typically get a better deal than booking each component individually. And you'll still have the freedom to create a customized Irene vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Irene?
If you've got your Irene travel dates locked in, book as soon as you can to score some incredible deals. With Expedia, you can generally reserve some flights up to one year ahead of time. Prefer spontaneous adventures? Our last-minute deals are ideal for setting off on a whim.
How to plan a trip to Irene?

  1. Choose when to go: Check your calendar and get packing. Your favorite time of year and the activities on offer will also help you decide when to escape to Irene.
  2. Calculate your budget: Make sure you have enough money to cover everything from transportation and food to flights and activities. Your accommodations will likely be the largest expense during your trip to Irene.
  3. Decide how long to go for: Now that you know more about Irene, you can work out the perfect length of your break. Put together a rough plan and give yourself enough time to get through everything on your must-do list.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Irene vacation package.