Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art scene and churches in this vibrant area.
Brancacci Chapel
You can learn about the history of Florence with a stop at Brancacci Chapel. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Ponte Vecchio
Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the notable monuments and stunning cathedral in this vibrant area.
Cathedral of Santa Maria del Fiore
Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the fascinating museums and acclaimed art scene in this vibrant area.
Uffizi Gallery
Uffizi Gallery is a top museum in Florence with a rich history. Stroll along the riverfront or visit the notable monuments in this vibrant area.
Santo Spirito Hotel Deals
Hotel Horto Convento
Great hotel all around and great breakfast. Highly recommend and will go back when in Florence
Reviewed on 19 April 2026
Palazzo Mannaioni Suites
Great location. Clean room. Great staff.
Reviewed on 22 April 2026
La Torre Del Cestello
The room was not at all as shown. The hotel lobby isn’t a lobby but a small room with a check in desk on the 3 floor. There is only a few rooms. This is not a hotel. The cafe/bar on the lower level is loud with extremely loud music and they go until 4 am. We could not sleep. The main chandelier in ...
Reviewed on 20 April 2026
UNA Hotels Vittoria Firenze
Helpful staff. Vey good breakfast. Clean and comfortable room.
Reviewed on 1 April 2026
Foresteria Valdese di Firenze - Casa per Ferie
The staff was amazing.
Reviewed on 10 April 2026
1900 Artevita
Huge room on the outskirts of the city centre. Lovely area with great restaurants. The room was exceptionally clean, the downside was the very hard bed as we prefer a softer bed. We would definitely come back here if we returned to Florence.
Reviewed on 10 April 2026
Other neighborhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
