Cherokee Vacation Rentals

Q: What are some of the best vacation home rentals that Cherokee has to offer?

Restful on Rhody : This vacation home rental outside of Cherokee is located on a lake and has a fireplace, a balcony, and WiFi to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Kick off your shoes and enjoy yourself with a garden and an arcade game room.

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Dates

November 2026

December 2026

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Our top choices for Cherokee vacation rentals

A modern two-story house with a balcony, garage, and a number '307' on the garage door.

1. NEW 1BR efficiency apartment in Johnson City

Johnson City

Kyle S.

SAR 800 total

includes taxes & fees

20 Nov - 21 Nov

A compact living space with a bed, a sofa, a dining table with chairs, a kitchen area, and a sliding glass door leading to an outdoor area.

2. Welcoming Tiny House close to ETSU, Medical Center and Downtown Johnson City, TN

Johnson City

Jan L.

SAR 680 total

includes taxes & fees

8 Nov - 9 Nov

A wooden cabin with a bear statue on the porch, wooden chairs, and a view of trees.

3. ❤️Unique Cabin studio, in Heart of the tri cities

Bluff City

Mike

SAR 536 total

includes taxes & fees

2 Dec - 3 Dec

A room with a wooden cabinet, a television on top, a small table with a magazine, and a grey rug on the floor.

4. Quiet Retreat in the Tree Streets!

Johnson City

Alexandria William B.

SAR 531 total

includes taxes & fees

9 Nov - 10 Nov

A modern kitchen with white cabinets, a stainless steel refrigerator, and a tiled backsplash.

5. Downtown Johnson City Loft: Pet-Friendly & Walk 201

Johnson City

Matthew

A modern kitchen with white cabinets, a black countertop, and two yellow bar stools.

6. Stay in heart of Johnson City - Urban Loft

Johnson City

Frances M.

SAR 1,221 total

includes taxes & fees

20 Nov - 21 Nov

A modern living room with a grey sofa, a round wooden coffee table, and a dining area with a white table and chairs.

7. The Blue Loft on Main | Walkable Downtown Stay

Johnson City

A modern kitchen with white cabinets, a wooden dining table, and a window with blinds.

8. Lamont 6 1Bed Pet-Friendly Apt

Johnson City

Kelli H.

A wooden deck with a 'WELCOME' sign, a green watering can, and decorative shelves with plants and a birdcage.

9. Lou's Loft of Hampton, TN

Hampton

Marilyn

SAR 566 total

includes taxes & fees

20 Nov - 21 Nov

A cozy cabin interior with a wooden floor, a sofa, a chair, a table with books, a lamp, and a view of a forest through large windows.

10. Peacocks, blacksmithing, buffalo, wildlife, a studio cabin by the pond.

Unicoi

Stephanie W.

SAR 661 total

includes taxes & fees

7 Nov - 8 Nov

A covered porch with wicker furniture and a wooden deck.

11. Modern Pet-Friendly Apt near Downtown Johnson City L5

Johnson City

Katie

A spacious living room with a dark wooden floor, a sofa set, a coffee table, and a side table with a lamp.

12. Amazing 1 Bedroom Apartment, Downtown Jonesborough

Jonesborough

Rick R.

SAR 1,060 total

includes taxes & fees

20 Nov - 21 Nov

A kitchen with a wooden table, a vase with flowers, and a window with natural light.

13. Remodeled 2BR · Steps to ETSU · Pets Welcome

Johnson City

Lori V.

SAR 1,330 total

includes taxes & fees

20 Nov - 21 Nov

A modern living room with a grey sectional sofa, a wall-mounted TV, and a window with blue curtains.

14. Buc-Themed 2BR Condo · Two En Suites · 5 Min to ETSU, JCMC & the VA

Johnson City

Richard T.

A two-story wooden cabin with a balcony, situated in a grassy field.

15. ❤️Relaxing Cabin studio, in Heart of the tri citie

Bluff City

Angela C.

SAR 540 total

includes taxes & fees

7 Dec - 8 Dec

A kitchen with white cabinets, a stainless steel refrigerator, a granite countertop, two bar stools, and a potted plant.

16. Pet-Friendly Loft Downtown Near Dining & Parks 203

Johnson City

Christine B.

A modern living room with a green sofa, a round wooden coffee table, and a kitchen in the background.

17. Charming 1-bedroom apartment in welcoming Johnson City with AC

Johnson City

Angel E.

SAR 1,144 total

includes taxes & fees

20 Nov - 21 Nov

A wooden deck with a sofa, chairs, and a table, overlooking a forested valley.

18. Spacious Apartment with Scenic Deck Views

Johnson City

Todd M.

SAR 1,059 total

includes taxes & fees

20 Nov - 21 Nov

A building with a brick facade, black awning, and outdoor seating area with tables and chairs.

19. Downtown JC Apt: Courtyard View & Pet-Friendly 203

Johnson City

Derek H.

A living room with a fireplace, a television mounted on the wall, and a door with a window.

20. 3BR house in neighborhood with ETSU, JCMC, VA

Johnson City

Penny P.

SAR 1,203 total

includes taxes & fees

7 Dec - 8 Dec

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Find vacation rentals that suit your style

Top Cherokee Hotel Reviews

A bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

Carnegie Hotel & Spa

Johnson City

10/10 Excellent

Susan

A modern living room with a stone fireplace, a blue sectional sofa, and a wooden reception desk.

Fairfield Inn & Suites by Marriott Johnson City

Johnson City

10/10 Excellent

Donna

An outdoor seating area with sofas, chairs, and a fire feature.

Home2 Suites by Hilton Johnson City, TN

Johnson City

10/10 Excellent

Glyne

A snack kiosk with various packaged snacks and a vending machine area.

Hampton Inn Johnson City

Johnson City

10/10 Excellent

I chose this hotel while interviewing at ETSU and was not disappointed. The staff was friendly and welcoming, the room clean, and the hotel quiet. We chose a room with a jacuzzi tub and it was a great way to relax after a long and exhausting day. The hotel is located close to many great restaurants and stores, so there are plenty of options to explore. The pillows were a little uncomfortable and I would recommend bringing your own, but otherwise a great stay!

Brittany

A modern kitchen with dark wood cabinets, stainless steel appliances, and a central island with seating.

Staybridge Suites By Holiday Inn Johnson City by IHG

Johnson City

10/10 Excellent

Our stay for 2 nights was heaven. The beds were like sleeping on a marshmallow. Just the right softness and I had no problem sleeping that night. We found everything so clean and inviting. It was a little outdated. The couch was low and so was the chair. I am handicapped and I had to be helped off the couch. It was uncomfortable also. The bathroom needs some sort of heavy glass. Running to the kitchen for a glass is dumb. I had a handful of medication and needed a glass. To the kitchen for a...

Wendy

A Sleep Inn hotel with a modern design, featuring a prominent entrance and a parking lot.

Sleep Inn & Suites Johnson City

Johnson City

10/10 Excellent

Abby

An indoor swimming pool with checkered flooring, surrounded by brick walls and large windows.

DoubleTree by Hilton Hotel Johnson City

Johnson City

10/10 Excellent

William

A wooden gazebo with a clear blue sky in the background.

Holiday Inn Express Hotel and Suites Kingsport by IHG

Kingsport

10/10 Excellent

Jessica

A hotel room with a large bed, a sofa, a small table, and a nightstand with a lamp.

Comfort Suites Johnson City near University

Johnson City

10/10 Excellent

Paul

A hotel room with a flat-screen TV, a sofa, a small table, a bed, and large windows offering a view of greenery.

Hampton Inn Kingsport

Kingsport

10/10 Excellent

Bob

A modern living room with a fireplace, green armchairs, a round coffee table, and a stone accent wall.

Fairfield Inn & Suites by Marriott Kingsport

Kingsport

10/10 Excellent

A Great Easy Location to get to & from to all of the eating establishments & attractions in the area. Upon check in, I was greeted warmly by a wonderful staffer, she made me feel welcome & offered any assistance during my Stay; later she gave me Fabulous Directions to the Conference I was attending + gave me a tasty menu recommendation when she gave me additional driving directions to meet friends for Dinner; she also directed me to the Airport the evening before I checked out. I had another...

Caron Marie

A spacious lobby with a blue sofa, a round coffee table, and a reception desk.

Comfort Suites Kingsport South

Kingsport

10/10 Excellent

Anonymous traveler

A modern reception area with a glass coffee table, leather seating, and a reception desk with a sign reading "Quality Inn."

Quality Inn Johnson City near Downtown

Johnson City

10/10 Excellent

George

A spacious lobby with a blue accent wall, a staircase, seating area, and a view of the outdoors.

Sleep Inn & Suites Kingsport TriCities Airport

Blountville

10/10 Excellent

Sharon

Frequently Asked Questions

Are there vacation rentals in Cherokee?

Yes, we have vacation rentals near top points of interest in Cherokee, or you can go with a more remote option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Cherokee has to offer?

Restful on Rhody: This vacation home rental outside of Cherokee is located on a lake and has a fireplace, a balcony, and WiFi to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Kick off your shoes and enjoy yourself with a garden and an arcade game room.

What can I see and do in Cherokee?

Explore the area and family-friendly sights such as Wetlands Water Park, or get out into nature at a spot like Tweetsie Trail Trailhead. In the larger area, you’ll find East Tennessee State University and Yee-Haw Brewing Company.

What’s a vacation rental in Cherokee like?

Vacation rentals are private properties you can reserve for several days or longer in Cherokee. Vacation rentals feature extras like laundry facilities and kitchens so you'll have all the conveniences of home. If you're concerned about a clean environment, a vacation rental can provide a sense of privacy away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.

Cherokee Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Cherokee vacation rentals

1. NEW 1BR efficiency apartment in Johnson City

2. Welcoming Tiny House close to ETSU, Medical Center and Downtown Johnson City, TN

3. ❤️Unique Cabin studio, in Heart of the tri cities

4. Quiet Retreat in the Tree Streets!

5. Downtown Johnson City Loft: Pet-Friendly & Walk 201

6. Stay in heart of Johnson City - Urban Loft

7. The Blue Loft on Main | Walkable Downtown Stay

8. Lamont 6 1Bed Pet-Friendly Apt

9. Lou's Loft of Hampton, TN

10. Peacocks, blacksmithing, buffalo, wildlife, a studio cabin by the pond.

11. Modern Pet-Friendly Apt near Downtown Johnson City L5

12. Amazing 1 Bedroom Apartment, Downtown Jonesborough

13. Remodeled 2BR · Steps to ETSU · Pets Welcome

14. Buc-Themed 2BR Condo · Two En Suites · 5 Min to ETSU, JCMC & the VA

15. ❤️Relaxing Cabin studio, in Heart of the tri citie

16. Pet-Friendly Loft Downtown Near Dining & Parks 203

17. Charming 1-bedroom apartment in welcoming Johnson City with AC

18. Spacious Apartment with Scenic Deck Views

19. Downtown JC Apt: Courtyard View & Pet-Friendly 203

20. 3BR house in neighborhood with ETSU, JCMC, VA

Find vacation rentals that suit your style

Top Cherokee Hotel Reviews

Carnegie Hotel & Spa

10/10 Excellent

Frequently Asked Questions

Are there vacation rentals in Cherokee?

What are some of the best vacation home rentals that Cherokee has to offer?

What can I see and do in Cherokee?

What’s a vacation rental in Cherokee like?