The Best Hotels Closest to Buffalo Museum of Science in Buffalo for 2026

Our top choices for Buffalo Museum of Science hotels

InnBuffalo off Elmwood

Elmwood Village, 3 km from Buffalo Museum of Science

Beth

SAR 861 total

includes taxes & fees

2 Jun - 3 Jun

Buffalo Harmony House

Allentown, 3.2 km from Buffalo Museum of Science

Dustin

SAR 1,073 total

includes taxes & fees

28 Jun - 29 Jun

The Edward Hotel

Elmwood Village, 2.4 km from Buffalo Museum of Science

Catherine

SAR 693 total

includes taxes & fees

31 May - 1 Jun

Wyndham Garden Buffalo Downtown

Downtown Buffalo, 1.9 km from Buffalo Museum of Science

Stephen

SAR 697 total

includes taxes & fees

31 May - 1 Jun

The Mansion On Delaware Ave

Allentown, 3 km from Buffalo Museum of Science

Olga

SAR 997 total

includes taxes & fees

31 May - 1 Jun

Buffalo Guesthouse

Allentown, 2.4 km from Buffalo Museum of Science

Joseph

SAR 622 total

includes taxes & fees

30 May - 31 May

Residence Inn by Marriott Buffalo Downtown

Allentown, 2.6 km from Buffalo Museum of Science

Carlos

SAR 1,514 total

includes taxes & fees

28 Jun - 29 Jun

Lenox Hotel and Suites

Allentown, 2.6 km from Buffalo Museum of Science

Richard

SAR 438 total

includes taxes & fees

31 May - 1 Jun

Suite, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

Best Western on the Avenue

Allentown, 2.8 km from Buffalo Museum of Science

Brian

SAR 666 total

includes taxes & fees

21 Jun - 22 Jun

1 bedroom, in-room safe, desk, laptop workspace

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 3.1 km from Buffalo Museum of Science

Deb

SAR 596 total

includes taxes & fees

11 Jun - 12 Jun

Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 3 km from Buffalo Museum of Science

Dean

SAR 1,012 total

includes taxes & fees

21 Jun - 22 Jun

4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.4 km from Buffalo Museum of Science

SAR 1,972 total

includes taxes & fees

4 Jun - 5 Jun

Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 3.4 km from Buffalo Museum of Science

Jessica

SAR 1,120 total

includes taxes & fees

31 May - 1 Jun

Reikart House, Buffalo, a Tribute Portfolio Hotel

8.3 km from Buffalo Museum of Science

Michael

SAR 1,071 total

includes taxes & fees

5 Jun - 6 Jun

55-inch Smart TV with satellite channels, TV, Netflix

Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 4.4 km from Buffalo Museum of Science

Carna

SAR 1,140 total

includes taxes & fees

14 Jun - 15 Jun

The Westin Buffalo

Buffalo Theater District, 3.3 km from Buffalo Museum of Science

Michaline

SAR 1,152 total

includes taxes & fees

14 Jun - 15 Jun

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

9 km from Buffalo Museum of Science

Shadane

SAR 905 total

includes taxes & fees

29 May - 30 May

Salvatores Grand Hotel

13.1 km from Buffalo Museum of Science

Ethan

SAR 551 total

includes taxes & fees

31 May - 1 Jun

Hampton Inn Buffalo - Amherst, NY

10.6 km from Buffalo Museum of Science

SONNY

SAR 522 total

includes taxes & fees

14 Jun - 15 Jun

The Richardson Hotel

Elmwood Bidwell, 4 km from Buffalo Museum of Science

doris

SAR 686 total

includes taxes & fees

3 Jun - 4 Jun

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Compare popular hotels close to Buffalo Museum of Science

Property	Property class	Guest rating
InnBuffalo off Elmwood	2.5 star property	10.0 Exceptional 218 reviews	View
Buffalo Harmony House	4.5 star property	10.0 Exceptional 51 reviews	View
The Edward Hotel	3.0 star property	9.6 Exceptional 241 reviews	View
Wyndham Garden Buffalo Downtown	3.0 star property	9.0 Wonderful 1,822 reviews	View
The Mansion On Delaware Ave	4.0 star property	9.4 Exceptional 1,007 reviews	View

Top Buffalo Museum of Science Hotel Reviews

Buffalo Guesthouse

10/10 Excellent

"The staff was very nice and the property was a far more interesting stay than a typical hotel which was a benefit. The shower could have been a little cleaner but, the stay was good!"

The Edward Hotel

10/10 Excellent

"The Edward is a hidden gem in the Elmwood area of Buffalo. The room was large and spacious. It had nice amenities as well, including an area off the lobby for people to gather. Check in was super easy and the staff checked in every day with us to make sure we had everything we needed. There are only 6 parking spots on site, but on street parking was available. Very lovely - would definitely stay there again!"

Best Western on the Avenue

10/10 Excellent

"We had an excellent visit to Best Western On The Avenue! The front desk staff were lovely upon arrival and check-in was a breeze. We were very pleasantly surprised with the Jetted Tub room where the Whirlpool hot tub was clean and functioned perfectly. The bathroom was ideal with a large shower, mirrors and a very unique red light bulb option. The Keurig, microwave and fridge in room were great amenities. The hotel was walking distance from plenty of bars and restaurants on beautiful Allen St. We loved being greeted by our new bird friend Simba at the front desk whenever we passed. The TV in-room had cable but we weren’t able to figure out the streaming apps / TV WiFi component. Can’t wait for our next stay!"

Fabulous 3-bedroom house with AC in charming Buffalo

10/10 Excellent

"We went to Buffalo for my son's wedding. This was the perfect place for us. Very spacious, comfortable couches, new kitchen and bathroom, great little space for shoes and coats and a great porch where we enjoyed coffee in the morning and a glass of wine at night. There's a little coffee bar and there were cold bottles of water in the fridge waiting for us. We also appreciated how very clean it was. It's near a large park where my son went jogging and it's a short walk on a sidewalked street to dollar general in case you need to get some supplies. Would absolutely stay here again."

Hotels near other Buffalo Museum of Science attractions

Buffalo Central Terminal

You can find out about the history of Buffalo when you stop by Buffalo Central Terminal. Experience the great live music and acclaimed theater scene in this vibrant area.

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Frequently asked questions

What's the area like around Buffalo Museum of Science?

Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, check out the 13 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Buffalo Museum of Science?

Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. It's located 1.2 mi (1.9 km) from Buffalo Museum of Science. Other good choices within 5 miles include Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG and Hyatt Regency Buffalo / Hotel and Conference Center.

How many hotels will I be able to find close to Buffalo Museum of Science?

Expedia has 13 hotels and other accommodations within a mile from Buffalo Museum of Science.

If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Buffalo Museum of Science.

Where can I learn more about changing or cancelling my trip in the area near Buffalo Museum of Science?

For more information about picking new dates or cancelling your stay near Buffalo Museum of Science, go to https://www.expedia.com/service/.

What can I see and do near Buffalo Museum of Science?

Study the collections at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, Buffalo AKG Art Museum, or Buffalo History Museum. Some landmarks that you won't want to miss include Buffalo Central Terminal, Statler Tower, and Ellicott Square Building. You can watch performances at Kleinhans Music Hall, Paul Robeson Theater, and Ujima Theatre Company if you're interested in local theater.

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Our top choices for Buffalo Museum of Science hotels

InnBuffalo off Elmwood

Buffalo Harmony House

The Edward Hotel

Wyndham Garden Buffalo Downtown

The Mansion On Delaware Ave

Buffalo Guesthouse

Residence Inn by Marriott Buffalo Downtown

Lenox Hotel and Suites

Best Western on the Avenue

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Aloft by Marriott Buffalo Downtown

4 Mi to Dtwn: Family Home in Buffalo

Curtiss Hotel, an Ascend Collection Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel

Buffalo Marriott at LECOM HARBORCENTER

The Westin Buffalo

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

Salvatores Grand Hotel

Hampton Inn Buffalo - Amherst, NY

The Richardson Hotel

Compare popular hotels close to Buffalo Museum of Science

Top Buffalo Museum of Science Hotel Reviews

Buffalo Guesthouse

Hotels near other Buffalo Museum of Science attractions

Buffalo Central Terminal

Frequently asked questions

Explore a world of travel with Expedia

Hotels near popular Buffalo Attractions

Other Hotels near Buffalo Museum of Science, MLK Park

More Hotel Options in Buffalo Museum of Science

Explore more hotels