Adrian, TX

Travel Guide

A signpost with distance markers for Chicago and Los Angeles.

A road with 'Midpoint' marking, a 'Welcome' sign, and a 'Route 66' symbol.

A road with a white line marking and a Route 66 sign.

A welcome sign for Route 66 with a windmill and wind turbines in the background.

A welcome sign for Adrian, Texas, indicating it is the midpoint of Route 66 between Los Angeles and Chicago, each 1139 miles away.

Visit Adrian

Route 66 Desert Rose Country Inn

1800 West Vega Boulevard Vega TX

Fully refundableReserve now, pay when you stay

SAR 258

SAR 289 total

12 Oct - 13 Oct

includes taxes & fees

Book a stay at this business-friendly hotel in Vega. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...

8/10 Very Good! (429 reviews)

"Tf"

Reviewed on 27 September 2026

Days Inn by Wyndham Vega TX

1005 S Main St Vega TX

SAR 345

SAR 386 total

5 Oct - 6 Oct

includes taxes & fees

Stay at this hotel in Vega. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Magnolia Gas Station is located nearby.

Route 66 Retreat

Vega TX

Stay at this vacation home in Vega. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attraction Magnolia Gas Station is located ...

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See all 3 properties in Adrian

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Route 66 Retreat

Vega TX

Stay at this vacation home in Vega. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attraction Magnolia Gas Station is located ...

See all properties in Adrian

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.