Find 5 Star Hotels in Santee, SC

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Check availability on Santee 5 Star Hotels

Tonight
25 Feb - 26 Feb
Tomorrow
26 Feb - 27 Feb
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santee.
Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

401 Bass Drive Santee SC
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

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Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Santee?
How much you pay for a 5-star hotel in Santee can vary depending on what time of year you travel and how long you plan to stay, among a range of factors. Take advantage of our price per night filter and other search tools to find the best rate on a high-end stay.

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What makes a hotel 5 stars in Santee?
From fine dining restaurants and 24-hour gyms to swimming pools and luxury bedding, the 5-star experience in Santee is all about indulgence and comfort. But it requires more than just top-notch perks to earn a 5-star rating. Accommodations also have to offer remarkable guest-focused services like in-room beauty treatments, on-site laundry and dry cleaning and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Santee?
Find an indulgent getaway that includes your room, meals, activities and entertainment in Santee with our filters. Search for properties with a 5-star rating and select the "All inclusive" filter. Be sure to check what's included in the purchase price. That way, you're ready to take advantage of the premium perks on offer as soon as you arrive.