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Compare Isla Grande 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Ordovician Beach Resort
Isla Grande
10.0 out of 10, Exceptional, (3)

El Otro Lado
Portobelo
9.8 out of 10, Exceptional, (8)

Portobello Historico
Portobelo
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Learn more about Isla Grande
Snorkel through crystal-clear waters to spot colorful coral reefs and tropical fish just off the white-sand beaches. Hike to the historic Spanish fort on the island's edge or take boat tours to nearby Portobelo National Park.

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Isla Grande Hotels by Star Rating
Stay near popular Isla Grande attractions
- Hotels near Blanca Beach
- Hotels near Isla Mamey
- Hotels near Chagres National Park
- Hotels near Playa La Angosta
- Hotels near Portobelo National Park
- Hotels near San Felipe Church
- Hotels near Real Aduana de Portobelo
- Hotels near Fuerte San Fernando
- Hotels near Safarick's Zoo
- Hotels near Mirador Perú
- Hotels near Fuerte San Jerónimo
- Hotels near Fuerte Santiago
More Accommodation Types in Isla Grande
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- Spacious Beach House on the ocean front with huge pool and patio.
- ScubaPortobelo
- BEAUTIFUL APARTMENT IN FRONT OF THE SEA
- Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
- Cabaña La Punta op het Strand!!
- Piscina Mar en el Paraíso Caribe
- BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES
- Caribbean Beach House with Pool
- Casa Frente al Mar - Isla Grande
- Perfect getaway to the sea - Family apartment in exclusive Resort
- Caribbean getaway: beach cottage just on the sand
- Caribbean Paradise - Beachfront Getaway
- Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual
- Kasa Leilani, the perfect Caribbean gateway!
- Nice house in Portobelo, Skybluebyguanche
- Pebos Reef with amazing terrace over the sea - apartment #1
- Cara al mar Cacique
- A fantastic place between the sea and the jungle
- Casa Anzuelo is an oceanfront home that is all about the water and nature.
- Despierta sobre el mar









