A calm sea with a small boat and a row of palm trees on the shore.

Find 4 Star Hotels in Eastern Panama from SAR 1,742

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Check availability on Eastern Panama 4 Star Hotels

Tonight
18 Sep - 19 Sep
Tomorrow
19 Sep - 20 Sep
This weekend
18 Sep - 20 Sep
Next weekend
25 Sep - 27 Sep

Our top choices for Eastern Panama 4-star hotels

1. Ordovician Beach Resort

Ordovician Beach Resort
Isla Grande
Canada
Janet
SAR 1,577
SAR 1,742 total
includes taxes & fees
21 Sep - 22 Sep
Ordovician Beach Resort

2. Mandalas Ecolodge

Mandalas Ecolodge
Caimitillo
Mandalas Ecolodge

3. El Otro Lado

El Otro Lado
Portobelo
United States
Jacob
El Otro Lado

4. Portobello Historico

Portobello Historico
Portobelo
Portobello Historico
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Learn more about Eastern Panama

Explore attractions like Cayos Holandeses and Chagres National Park as you discover things to see and do in Eastern Panama.

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A man in a canoe with a sail on a turquoise sea, surrounded by palm trees.
Photo by ‎Katsmeow43

Top Eastern Panama Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Eastern Panama?
With Expedia's handy filter tool, scoring an awesome deal on a 4-star hotel in Eastern Panama just got simpler. Start by keying in your chosen arrival date and length of your vacation. Then sort the results by price and pick the option that best matches your budget and style.
  • Search for the lowest price from SAR 1,742
What's the difference between 5-star and 4-star hotels in Eastern Panama?
If you decide to book a stay at a 4-star hotel in Eastern Panama, you'll usually find lots of conveniences to keep you comfortable, such as a pool, restaurant and gym. You can experience top-quality service and upscale accommodations. Go for a 5-star hotel and you'll have access to a few more bells and whistles — think on-site spas, concierge assistance and nightly turndown services. You'll most likely get extra amenities and premium services at a 5-star retreat, but both are terrific options for luxury guests.
Does Eastern Panama have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Eastern Panama where just about everything is taken care of, from your meals to your accommodations, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.