Downtown Clayton, MO
St. Louis
Visit Downtown Clayton
Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
"Great for a quick overnight stay!"
Reviewed on 25 July 2026
Le Méridien St. Louis Clayton
"Very cute hotel- clean, workers were kind and helpful. Pool was beautiful, drinks were good, and snacks were yummy. Highly recommend."
Reviewed on 25 July 2026
AC Hotel St. Louis Clayton
Hyatt Regency St. Louis at The Arch
"Very friendly and helpful customer service, clean room"
Reviewed on 25 July 2026
Hollywood Casino & Hotel St. Louis
"Checking in is easy & rooms are pretty decent, paying for wifi and parking with no breakfast included is a negative but proximity to the concerts is a plus."
Reviewed on 25 July 2026
Pear Tree Inn St. Louis Airport
Where to stay in Downtown Clayton
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Central West End
The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
