Santa MarĆ­a Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to SARĀ 5,400 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Santa MarĆ­a Vacation Packages

Santa MarĆ­a Hotel Deals

OZ Hotel Collection

OZ Hotel Collection

4.5 out of 5
6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
The price is SARĀ 461 per night from Aug 9 to Aug 10
SARĀ 461
SARĀ 461 total
9 Aug - 10 Aug
9.6/10 Exceptional! (623 reviews)
"Everything was excellent"

Reviewed on 20 July 2026

OZ Hotel Collection
Hilton Cartagena

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
The price is SARĀ 767 per night from Aug 16 to Aug 17
SARĀ 767
SARĀ 767 total
16 Aug - 17 Aug
Hilton Cartagena
Holiday Inn Express Cartagena Bocagrande by IHG

Holiday Inn Express Cartagena Bocagrande by IHG

4 out of 5
Avenida San Martin Cra 2 N 9-54 Cartagena Bolivar
Fully refundable
The price is SARĀ 445 per night from Aug 9 to Aug 10
SARĀ 445
SARĀ 445 total
9 Aug - 10 Aug
Holiday Inn Express Cartagena Bocagrande by IHG
See all 4,033 properties in Santa MarĆ­a
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa MarĆ­a vacation package cost?
Offering excellent value package deals on Expedia, you'll be surprised at how little a vacation to Santa MarĆ­a costs! Our packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Santa MarĆ­a?
You can usually find lower rates and greater availability in April, September and October. Browse our cheap Santa MarĆ­a vacation packages and you could get some great off-season deals.
How to find the best Santa MarĆ­a package deals?
Finding a cheap Santa MarĆ­a package deal is a breeze with Expedia. After you've entered your destination and trip dates under our "Packages" tab, set your maximum budget, apply a few filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most economical Santa MarĆ­a package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santa MarĆ­a vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking flights and stays individually. Better still, you can tailor your Santa MarĆ­a getaway to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa MarĆ­a?
If you've got your Santa MarĆ­a travel dates locked in, book as early as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for jetting off on a whim.
How to plan a trip to Santa MarĆ­a?

  1. Choose your travel dates: What you want to do in Santa MarĆ­an and your preferred season can help you decide when to get away.
  2. Set your budget: Factor in costs such as flights, meals and transportation when working out how much to set aside for your trip to Santa MarĆ­a. Then, select a hotel that suits your budget, whether that's an affordable stay or a high-end retreat.
  3. Decide how long to go away for: Now that you're up to speed on Santa MarĆ­a, you can work out the perfect length of your break. Create a draft plan and allocate enough time to get through everything on your must-do list.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Santa MarĆ­a vacation package.