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Check prices for these dates

Tonight
18 Sep - 19 Sep
Tomorrow
19 Sep - 20 Sep
This weekend
18 Sep - 20 Sep
Next weekend
25 Sep - 27 Sep

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Star rating

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Our top choices for San Francisco hotels

Outdoor pool
Restaurant
Front of property
Deluxe Single Room | Desk, laptop workspace, WiFi (free)

1. HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
United States
Hedwig
SAR 287
SAR 316 total
includes taxes & fees
21 Sep - 22 Sep
HOTEL VISTA LAGO
Interior
Junior Studio Suite | Interior
Interior
Junior Studio Suite | Desk, blackout drapes, iron/ironing board (on request), WiFi (free)

2. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
SAR 195
SAR 214 total
includes taxes & fees
19 Sep - 20 Sep
Hotel Plaza Los Tucanes
Outdoor pool, free cabanas, pool umbrellas
Exterior
Interior detail
Free daily cooked-to-order breakfast

3. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
SAR 273
SAR 300 total
includes taxes & fees
19 Sep - 20 Sep
Hotel Gran David
3 outdoor pools, free cabanas, pool umbrellas
3 outdoor pools, free cabanas, pool umbrellas
Lobby sitting area
Free daily cooked-to-order breakfast

4. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
SAR 308
SAR 341 total
includes taxes & fees
23 Sep - 24 Sep
Hotel Mykonos Panama
Restaurant
Exterior
Terrace/patio
Terrace/patio

5. Hotel Anachoreo

Hotel Anachoreo
Santa Fe
United States
John
SAR 318
SAR 349 total
includes taxes & fees
24 Sep - 25 Sep
Hotel Anachoreo
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Top San Francisco Hotel Reviews

Hotel Mykonos Panama

Hotel Mykonos Panama

10/10 Excellent
"Me encantó mi estadía en Hotel Mykonos. La habitación fue muy cómoda, mis hijos disfrutaron muchísimo la piscina y el servicio fue excelente. ❤️ Lo que más me encantó fue la comida del restaurante. La amapola (piña colada virgen) estaba espectacular, ¡10/10! 🍍🥥 De las mejores que he probado en Panamá. Además, la ubicación al lado de Santiago Mall es súper conveniente. Quedé muy satisfecha y definitivamente pienso regresar. ¡Mis hijos también quedaron encantados! 🙌❤️"
Nitza 1-night trip
Posted 3 days ago
Hotel Mykonos Panama
La Qhia Eco Retreat

La Qhia Eco Retreat

10/10 Excellent
"This is a beautiful property but remember it is somewhat rustic. The neighborhood roosters make sure to wake you. The rooms are comfortable and with the mountain air and ceiling fan you don’t miss AC. Free breakfast was tasty. Dinner was good but lunch is not available. The best part is the well maintained landscaping. We were fortunate to have a peaceful rainy day that was heaven on the covered patio with hammocks. The staff is friendly & helpful."
Patricia 3-night trip
Posted 7 days ago
La Qhia Eco Retreat
HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Balcony"
Carmen 1-night trip
Posted 13 days ago
HOTEL VISTA LAGO
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 3 weeks ago
Hotel Plaza Los Tucanes
Hotel Galería

Hotel Galería

10/10 Excellent
"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."
Lionel 1-night trip
Posted 6 months ago
Hotel Galería

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Frequently asked questions

What's the best place for a stay in San Francisco?
Hotel Mykonos Panama, located 10.4 mi (16.8 km) from the heart of San Francisco, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Hotel Gran David and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Francisco.
What are some of the best vacation rentals that San Francisco has to offer?
Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.: This vacation home rental outside of San Francisco is located in a rural location and offers a garden, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchenette with a stovetop, a microwave, and a coffee maker, so you can cook with friends or family. See all vacation rentals in San Francisco.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
To find more details about picking new dates or cancelling your trip to San Francisco, click here.
What is staying in San Francisco like?
Visitors to San Francisco are sure to find plenty to explore and enjoy. There are 18 hotels and other accommodations in the surrounding area. Find out more about San Francisco.
What should I see while I'm in San Francisco?
Places to visit in the wider area include Parque Acuatico Italia Guadalupe Panama, Laguna de La Yeguada, and Los Pozos Termales. You'll also find Omar Torrijos Herrera Stadium and Plaza Banconal in the area. Check out what more to see and do in Expedia's San Francisco guide.
What's the weather like in San Francisco?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in San Francisco are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.