Located in Rome City Centre, a neighborhood in Rome, Hotel Sant' Anna is near a metro station. St. Peter's Basilica and Vatican Museums are notable landmarks, and travelers looking to shop may want to visit Via del Corso and Via Veneto. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Visit our Rome travel guide
via borgo pio 134, Rome, RM, 00193
What's nearby
St. Peter's Square
2 min walk - 0.2 km
Via Cola di Rienzo
3 min walk - 0.3 km
St. Peter's Basilica
5 min walk - 0.5 km
Castel Sant'Angelo
7 min walk - 0.6 km
Sistine Chapel
7 min walk - 0.6 km
Getting around
Risorgimento/S. Pietro Tram Stop
4 min walk
Rome San Pietro Station
15 min walk
Ciampino Airport (CIA)
54 min drive
Restaurants
McDonald's
1 min walk
Pastasciutta
2 min walk
Trattoria Da Marcello
1 min walk
Ristorante Pizzeria Marcantonio
1 min walk
Caffe Moretto
2 min walk
About this property
Hotel Sant' Anna
Hotel near St. Peter's Square
A short walk from St. Peter's Basilica and Vatican Museums, Hotel Sant' Anna provides a garden and more. Guests can connect to free in-room WiFi.
Other perks at this hotel include:
Buffet breakfast (surcharge), luggage storage, and a 24-hour front desk
Concierge services and smoke-free premises
Guest reviews speak highly of the helpful staff and location
Room features
All guestrooms at Hotel Sant' Anna include perks such as air conditioning, in addition to amenities like free WiFi and safes.
Other amenities include:
Bidets, free toiletries, and hair dryers
Wardrobes/closets, electric kettles, and daily housekeeping
How much does it cost to stay at Hotel Sant' Anna?
As of 24 Shawwal 2026, prices found for a 1-night stay for 2 adults at Hotel Sant' Anna on 15 Dhuʻl-Qiʻdah 2026 start from SAR 704, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking?
This property doesn't offer parking.
What time is check-in at Hotel Sant' Anna?
Check-in start time: 1 PM; Check-in end time: midnight. Late check-in is available during limited hours.
What time is check-out at Hotel Sant' Anna?
Check-out is at 10:30 AM.
Where is Hotel Sant' Anna located?
Located in Rome City Centre, this hotel is within a 10-minute walk of St. Peter's Square, St. Peter's Basilica, and Sistine Chapel. Vatican Museums and Castel Sant'Angelo are also within 15 minutes. Risorgimento/S. Pietro Tram Stop is only a 4-minute walk and Ottaviano - San Pietro - Musei Vaticani Station is 9 minutes.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Hotel Sant' Anna Reviews
9.6
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.
This is a lovely hotel very close to St. Peter’s Cathedral and Vatican Museum. It’s about a 10 minute walk to the nearest Metro where we were able to explore other parts of the city. The staff was most helpful and charming restaurants are just outside the door.
Recommended! They were fast and responsive on Expedia chat beforehand. Fast check-in. Nice, cold A/C. Strong water pressure. Bidet. Fast, reliable Internet. All around a good experience.
We had a wonderful stay! The hotel was beautiful, impeccably maintained, and in the perfect location—just steps from Vatican City, making it incredibly convenient for sightseeing and attending events at St. Peter’s Basilica. The staff was exceptionally friendly, welcoming, and always eager to help with recommendations and any questions we had. Our room was comfortable and surprisingly spacious, with plenty of room for our family of four. We couldn’t have asked for a better place to stay in Rome and would gladly return!
Great historic hotel in a good neighborhood 3 blocks from St Peter’s Square. Many restaurants on the street and easily walkable as an old Rome neighborhood with the cobble stone streets. Closer to the Tiber and Castle San’Angelo. Lovely breakfast and friendly, helpful staff.
What an amazing experience. The staff are friendly and helpful (great recommendations for dinner), the hotel is charming, the neighbourhood is interesting and walkable, and the location is great.
The rooms are very clean and spacious.
The coffee and tea making was definitely a big plus for us.
We did not eat breakfast at the hotel as we had early tours booked.
There are great restaurants in the hotel street. We tried 6 of them and they were all had amazing food.
Stayed 4 nights in Jun 2026
Verified review
10/10 Excellent
John
6 November 2025
Liked: Cleanliness, staff & service, amenities
Rooms were immaculate, staff were courteous, breakfast was wonderful.
We stayed on several hotels in London, Paris, and Frankfurt during our trip though Europe. This was the only hotel that its air conditioning worked very well. We enjoyed their great location, about a block from the Vatican. There’s even a small convenience store around the corner where we could buy water and snacks and there’s also a lot of restaurants and gelato stores literally next door. The street in front of the hotel it’s for pedestrians only, so it’s quiet at night. The hotel offered a shuttle service to pick us up from the airport, at a price lower than Uber, though it has to be paid in cash to the driver. Their breakfast was great and reasonably priced. Overall we had a very good experience with this hotel. We highly recommend it.
This hotel is very quaint near everything to walk. The front desk was very nice and helpful and polite. Nice breakfast in the morning too. I would definitely stay here again.