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Check prices for these dates

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

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Our top choices for Main Street Fort Pierce hotels

A hotel lobby with a large reception desk, multiple seating areas, and a patterned carpet.

1. Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
3.0 star property
7.7 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1,005 reviews)
"This place is a blue collar, pet-friendly safe spot. The staff are friendly and helpful. Clean, decent breakfast and plenty of parking."
United States
Kirk
The price is SAR 348
SAR 390 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott Fort Pierce
A beach with a wooden pier, a thatched-roof structure, and beach chairs.

2. Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.2 out of 10, Very good, (1,373 reviews)
"Clean room nice staff and awesome view!! Will be staying there again soon!"
United States
Lana
The price is SAR 388
SAR 506 total
includes taxes & fees
3 Dec - 4 Dec
Hutchinson Island Hotel
A modern reception area with a long corridor, a reception desk, and a seating area with tables and chairs.

3. Holiday Inn Express Hotel & Suites Fort Pierce West by IHG

Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
2.5 star property
8.3 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (909 reviews)
"Clean rooms and bathrooms, breakfast and ample parking. The staff was very helpful as well"
United States
Dorisbell
The price is SAR 398
SAR 446 total
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
A modern hotel lobby with a central seating area, a bar, and a coffee station.

4. Hampton Inn & Suites Ft. Pierce

Hampton Inn & Suites Ft. Pierce
2.5 star property
7.9 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1,000 reviews)
"Rooms & common areas were clean & breakfast was good with a wide variety to choose from. Would stay here again."
United States
Ashton
The price is SAR 348
SAR 390 total
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn & Suites Ft. Pierce
An outdoor seating area with fire feature, stone walls, and a view into the building.

5. Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
7.8 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (278 reviews)
"Nice little breakfast...very clean and easy check in and check out..."
United States
JERRY
The price is SAR 475
SAR 532 total
includes taxes & fees
22 Nov - 23 Nov
Home2 Suites by Hilton Ft. Pierce I-95
A spacious living area with a grey sofa, a blue sofa, and a wooden accent wall with a flat-screen TV.

6. La Quinta Inn & Suites by Wyndham Ft. Pierce

La Quinta Inn & Suites by Wyndham Ft. Pierce
3.0 star property
7.9 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,005 reviews)
"Great property and service but they allow dogs to stay in the hotel and getting awaken by barking dogs is a no go"
United States
Willie
The price is SAR 330
SAR 370 total
includes taxes & fees
15 Nov - 16 Nov
La Quinta Inn & Suites by Wyndham Ft. Pierce
A hotel room with two beds, a nightstand, a wall-mounted lamp, and a sunset view painting.

7. Days Inn & Suites by Wyndham Fort Pierce Midtown

Days Inn & Suites by Wyndham Fort Pierce Midtown
2.0 star property
4.5 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (18 reviews)
"Very clean and convenient."
United States
Gary
The price is SAR 265
SAR 297 total
includes taxes & fees
11 Nov - 12 Nov
Days Inn & Suites by Wyndham Fort Pierce Midtown
A hotel room with a bed, a sofa, and a small table. There are framed pictures on the wall.

8. Comfort Suites Fort Pierce I-95

Comfort Suites Fort Pierce I-95
2.5 star property
7.7 km from Main Street Fort Pierce
7.8 out of 10, Good, (981 reviews)
"Clean rooms, friendly staff"
United States
Marina
The price is SAR 345
SAR 386 total
includes taxes & fees
11 Nov - 12 Nov
Comfort Suites Fort Pierce I-95
A hotel entrance with a welcome sign, a black mat, and two potted plants.

9. At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.2 out of 10, Very good, (1,386 reviews)
"Everything was great!"
United States
John
The price is SAR 198
SAR 222 total
includes taxes & fees
7 Dec - 8 Dec
At Home Inn
A hotel room with two beds, a television, a ceiling fan, and a view of the beach.

10. Royal Inn Beach Hotel Hutchinson Island

Royal Inn Beach Hotel Hutchinson Island
2.5 star property
3.8 km from Main Street Fort Pierce
7.2 out of 10, Good, (1,002 reviews)
"My go-to hotel when I need a place to get away!"
United States
Taylor
The price is SAR 405
SAR 514 total
includes taxes & fees
9 Nov - 10 Nov
Royal Inn Beach Hotel Hutchinson Island
A modern living room with a fireplace, a dining area with bar stools, and a large TV mounted on the wall.

11. Hampton Inn & Suites Vero Beach Downtown

Hampton Inn & Suites Vero Beach Downtown
2.5 star property
22.1 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1,000 reviews)
"Everything was excellent."
United States
Judith
The price is SAR 459
SAR 514 total
includes taxes & fees
6 Dec - 7 Dec
Hampton Inn & Suites Vero Beach Downtown
An outdoor seating area with wicker furniture, a fire pit, and palm trees.

12. Staybridge Suites Vero Beach by IHG

Staybridge Suites Vero Beach by IHG
3.0 star property
24.1 km from Main Street Fort Pierce
9.6 out of 10, Exceptional, (728 reviews)
"Perfect stay"
United States
Michelle
The price is SAR 465
SAR 521 total
includes taxes & fees
15 Nov - 16 Nov
Staybridge Suites Vero Beach by IHG
A multi-story hotel with a modern design, featuring a prominent sign for 'Springhill Suites Marriott'.

13. SpringHill Suites Port St. Lucie

SpringHill Suites Port St. Lucie
3.0 star property
17.2 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1,001 reviews)
"Loved our stay, great staff."
United States
Amy
The price is SAR 332
SAR 372 total
includes taxes & fees
15 Nov - 16 Nov
SpringHill Suites Port St. Lucie
A hotel lobby with seating areas, a kitchenette, and a view of the outdoors.

14. Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West
2.5 star property
17.4 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1,009 reviews)
"Very Helpful and Friendly staff, our room was super clean, and breakfast was great!"
United States
Ahim
The price is SAR 364
SAR 407 total
includes taxes & fees
6 Dec - 7 Dec
Hampton Inn & Suites Port St. Lucie, West
A Holiday Inn Express & Suites hotel with a modern design, featuring a prominent entrance, well-maintained landscaping, and a clear view of the sky.

15. Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG
2.5 star property
17.1 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,002 reviews)
"My stays there was pretty cool !!"
United States
Pierre Guens
The price is SAR 443
SAR 496 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express & Suites Port St. Lucie West by IHG
A hotel lobby with a reception desk, a chandelier, a clock, and a sofa.

16. Sleep Inn Fort Pierce I-95

Sleep Inn Fort Pierce I-95
2.5 star property
7.9 km from Main Street Fort Pierce
7.6 out of 10, Good, (927 reviews)
"Staff was very friendly and rooms were clean"
United States
Charity
The price is SAR 278
SAR 311 total
includes taxes & fees
29 Nov - 30 Nov
Sleep Inn Fort Pierce I-95
A hotel lobby with a reception desk, seating area, and a hallway leading to other rooms.

17. Days Inn & Suites by Wyndham Fort Pierce I-95

Days Inn & Suites by Wyndham Fort Pierce I-95
2.5 star property
7.8 km from Main Street Fort Pierce
7.4 out of 10, Good, (1,000 reviews)
"The staff was excellent"
United States
Carlton
The price is SAR 222
SAR 248 total
includes taxes & fees
29 Nov - 30 Nov
Days Inn & Suites by Wyndham Fort Pierce I-95
A clear blue swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a gazebo.

18. Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
14 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,004 reviews)
"Great stay"
United States
Patrisha
The price is SAR 338
SAR 378 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Port St. Lucie
A reception area with a wooden reception desk, a bulletin board with various notices, a window with blinds, and a wall-mounted security camera.

19. Rodeway Inn Fort Pierce US Highway 1

Rodeway Inn Fort Pierce US Highway 1
2.0 star property
2.9 km from Main Street Fort Pierce
6.8 out of 10, (126 reviews)
"Clean room, convenient location"
United States
Natalia
The price is SAR 321
SAR 359 total
includes taxes & fees
13 Nov - 14 Nov
Rodeway Inn Fort Pierce US Highway 1
A hotel room with a large bed, a desk, a chair, a bathroom, and a hallway.

20. Red Roof Inn Ft Pierce

Red Roof Inn Ft Pierce
2.0 star property
4.6 km from Main Street Fort Pierce
7.2 out of 10, Good, (819 reviews)
"Great place to stay as a family the day staff was wonderful when my hubby went to ask for an extra towel he was only given a had towel then had a fall in the shower due to no grip in the tub/shower but the room was up to par for the price pool was even still open"
United States
Sam
The price is SAR 285
SAR 320 total
includes taxes & fees
9 Nov - 10 Nov
Red Roof Inn Ft Pierce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Main Street Fort Pierce

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A modern hotel lobby with a central seating area, a bar, and a coffee station.
Hampton Inn & Suites Ft. Pierce
2.5 star property
9.2
Wonderful
1,000 reviews
View
A hotel lobby with a large reception desk, multiple seating areas, and a patterned carpet.
Fairfield Inn & Suites by Marriott Fort Pierce
3.0 star property
8.8
Excellent
1,005 reviews
View
A modern reception area with a long corridor, a reception desk, and a seating area with tables and chairs.
Holiday Inn Express Hotel & Suites Fort Pierce West by IHG
2.5 star property
9.0
Wonderful
909 reviews
View
An outdoor seating area with fire feature, stone walls, and a view into the building.
Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
9.4
Exceptional
278 reviews
View
A spacious living area with a grey sofa, a blue sofa, and a wooden accent wall with a flat-screen TV.
La Quinta Inn & Suites by Wyndham Ft. Pierce
3.0 star property
8.6
Excellent
1,005 reviews
View

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.
A coastal area with a narrow waterway, a beach, and residential buildings.

Lakewood Park

While Lakewood Park isn't home to many top sights, McKee Botanical Garden and Avalon State Park are some notable places to visit nearby.

Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Harbor Branch Ocean Discovery Center and McKee Botanical Garden.

A calm lake reflecting trees and a clear sky.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

A coastal city with a bay, mangrove islands, and a clear blue sky.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

A mosaic sign with 'Mainstreet Fort Pierce' written on it.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Endless Summer Vineyard & Winery and Al's Family Farms.

Top Main Street Fort Pierce Hotel Reviews

Best Western Downtown Stuart

Best Western Downtown Stuart

10/10 Excellent
"Very clean and well Maintained. We had a courtyard view which was very nice. Bed was comfortable and bathroom and shower was equally suitable. We wanted a place close to downtown and this was perfect. We would stay here again on our next visit to Stuart Stay there again on our ne"
Patricia 1-night trip
Posted 4 hours ago
Best Western Downtown Stuart

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Sunrise Theater and Fort Pierce Farmer's Market as part of your Main Street Fort Pierce travel plans.
How many hotels can I expect to find in Main Street Fort Pierce?
Book one of Expedia's 7 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.
Where can I learn more about changing or cancelling my trip to Main Street Fort Pierce?
For additional details about changing or cancelling your trip to Main Street Fort Pierce, head over to our customer service page.
What is there to do in this Fort Pierce neighborhood?
Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Fort Pierce Farmer's Market and Fort Pierce City Marina are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Manatee Education and Observation Center, House of Seven Gables, and A.E. Backus Museum. Marina at Fort Pierce and Causeway Cove are also worth a visit when you're out sightseeing in Fort Pierce.