The Best Hotels Closest to Historic Main Street in St. Louis for 2026

A brick-paved street lined with historic buildings and a yellow fire hydrant.

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Our top choices for Historic Main Street hotels

A brick building with a sign reading "Country Inn & Suites."

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

1. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District, 1 km from Historic Main Street

Roseanna

SAR 477

SAR 548 total

includes taxes & fees

1 Nov - 2 Nov

A large hotel with a prominent tower and multiple parking areas.

A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.

A spacious lobby with a patterned carpet, a reception desk, and a seating area with a sofa and chairs.

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

2. Hollywood Casino & Hotel St. Louis

3 km from Historic Main Street

Nicole

SAR 355

SAR 472 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

A bar area with multiple seating arrangements, a stage, and a chandelier.

3. Ameristar Casino Resort and Spa

1.4 km from Historic Main Street

Melissa

SAR 673

SAR 848 total

includes taxes & fees

13 Oct - 14 Oct

A modern lounge area with sofas, tables, and chairs, featuring a mix of seating arrangements and a central coffee station.

A modern lounge area with seating arrangements, tables, and hanging pendant lights.

A modern cafe with a self-serve beverage station, a central island with seating, and large windows offering a view.

4. Tru by Hilton St. Charles St. Louis, MO

2.1 km from Historic Main Street

Kippi

SAR 476

SAR 551 total

includes taxes & fees

1 Nov - 2 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A lobby with a wooden floor, a reception desk, a seating area with a red sofa, and a glass door leading to another room.

5. Comfort Suites St Charles - St Louis

1.5 km from Historic Main Street

Bryan

SAR 355

SAR 409 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, a desk with a television, a microwave, and a small refrigerator.

A modern kitchen with white cabinets, a long countertop, and overhead lighting.

6. Elimwood Hotel, a Ramada by Wyndham

3.1 km from Historic Main Street

Harry

SAR 265

SAR 310 total

includes taxes & fees

2 Nov - 3 Nov

A restaurant with a long wooden table, cushioned seating, and decorative lanterns.

A lobby with a checkered floor, a sofa, armchairs, a small table, and a water dispenser.

A compact kitchen with dark wooden cabinets, a built-in microwave, and a stainless steel refrigerator.

A hotel room with a kitchenette, a sofa, a desk, and a large window with curtains.

7. Holiday Inn St. Louis Arpt West-Earth City by IHG

2.9 km from Historic Main Street

Bryan

SAR 379

SAR 440 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a reception desk, seating area, and a fireplace.

A dining area with round tables and white chairs, a kitchen counter with appliances, and a framed picture on the wall.

A lobby with a fireplace, several potted plants, a television, and a sofa.

A living room with a beige sofa, a wooden coffee table, a patterned rug, a potted plant, and two framed pictures on the wall.

8. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1.6 km from Historic Main Street

Lynda

SAR 287

SAR 333 total

includes taxes & fees

13 Oct - 14 Oct

A spacious lobby with a central round table, two sofas, and a chandelier.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

9. Drury Plaza Hotel St. Louis Chesterfield

15.8 km from Historic Main Street

Chasity

SAR 488

SAR 566 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

A hotel room with a bed, a dresser, a nightstand with a lamp, a framed map on the wall, and a carpeted floor.

An outdoor patio area with a table and chairs, a glass door entrance, and a visible interior with a dining area.

A spacious lobby with a blue sofa, round coffee table, and blue chairs. There is a reception desk and a seating area with a high ceiling and large windows.

10. Drury Inn & Suites St. Louis St. Peters

12 km from Historic Main Street

Ashley

SAR 413

SAR 475 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

11. Hyatt Place St. Louis/Chesterfield

15.9 km from Historic Main Street

Debbie

SAR 453

SAR 525 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

12. Pear Tree Inn St. Louis Airport

10.6 km from Historic Main Street

Murphy

SAR 335

SAR 398 total

includes taxes & fees

19 Oct - 20 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

13. Wingate by Wyndham St. Louis Airport

10.7 km from Historic Main Street

Mary

SAR 364

SAR 432 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with a built-in grill, seating area, and stone walls.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.

A multi-story hotel with a parking lot in front.

14. Residence Inn by Marriott St. Louis Chesterfield

15.1 km from Historic Main Street

Chelsea

SAR 710

SAR 830 total

includes taxes & fees

18 Oct - 19 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

15. Hyatt Select St. Louis Airport

12 km from Historic Main Street

Daisy

SAR 413

SAR 512 total

includes taxes & fees

20 Oct - 21 Oct

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A modern lobby with a reception desk, seating area, and a dining section.

A Holiday Inn Express hotel with a modern design, featuring a covered entrance and multiple windows.

A coffee station with two coffee machines and a variety of coffee pods and cups.

16. Holiday Inn Express & Suites St Peters by IHG

15.7 km from Historic Main Street

Serah

SAR 443

SAR 533 total

includes taxes & fees

25 Oct - 26 Oct

A modern lounge area with a stone fireplace, a blue sofa, and a small table.

An indoor swimming pool with lounge chairs and tables, large windows, and a clock on the wall.

A Fairfield Inn & Suites Marriott hotel entrance with a modern design, featuring a brick facade, a covered entrance area, and a clear sky in the background.

A modern lobby with a blue sofa, a reception desk, and a snack bar.

17. Fairfield Inn & Suites St Louis Westport

9.5 km from Historic Main Street

Alan

SAR 492

SAR 576 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

18. Hampton Inn By Hilton St Louis Airport

11.7 km from Historic Main Street

Leia

SAR 484

SAR 582 total

includes taxes & fees

29 Oct - 30 Oct

An outdoor seating area with a table and chairs, a fire feature, and a brick wall.

A modern hotel with a flat roof, large windows, and a prominent signage for 'SPRINGHILL SUITES.'

A hotel lobby with a seating area, tables, and a TV screen.

A hotel room with a bed, bedside tables, a wardrobe, and a window with curtains.

19. SpringHill Suites by Marriott St. Louis Chesterfield

15.4 km from Historic Main Street

Jamie

SAR 459

SAR 533 total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a hot tub, a pool, and outdoor seating.

A modern coffee shop interior with wooden furniture, a coffee bar, and a sign for 'KELSO+BROS Coffee Roasters'.

A large conference room with rows of chairs, a patterned carpet, and a ceiling with recessed lighting and a chandelier.

A modern lounge area with grey armchairs, a sofa, a TV, and a bookshelf.

20. Drury Plaza Hotel St. Louis Creve Coeur

12.6 km from Historic Main Street

Eryn

SAR 492

SAR 572 total

includes taxes & fees

2 Nov - 3 Nov

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Compare popular hotels close to Historic Main Street

Property	Property class	Guest rating
Country Inn & Suites by Radisson, St. Charles Historic District	9.4 Exceptional 1,101 reviews	View
Hollywood Casino & Hotel St. Louis	8.6 Excellent 2,225 reviews	View
Ameristar Casino Resort and Spa	8.6 Excellent 1,075 reviews	View
Tru by Hilton St. Charles St. Louis, MO	8.6 Excellent 878 reviews	View
Comfort Suites St Charles - St Louis	8.4 Very good 1,005 reviews	View

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

8/10 Good

"Wonderful stay for a small bachelorette party. Had a wonderful time!"

Riverwood Retreat | Main Street 2BR

10/10 Excellent

"Very Good apt! Near everything!"

The Oak & Aura Retreat

10/10 Excellent

"The room was great. Very good location for the Oktoberfest. Very clean. We love the stay great communications."

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent

"They were excellent hosts and great communication!! I highly recommend this house!"

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

8/10 Good

"Great accessibility to shops and restaurants"

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent

"The Host ensured our needs were taken care. Perfect location!"

Driftwood Den | Boho 2BR | Dog-Friendly

10/10 Excellent

"Clean, easy parking, easy egress and ingress"

Main Street 2BR - Walk to Dining & Riverfront

10/10 Excellent

"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent

"Everything was exactly as described. St. Charles is an awesome place!"

Other attractions near Historic Main Street

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.

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A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)

You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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First Missouri State Capitol Historic Site

8.2/10 (25 reviews)

You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.

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Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)

You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lindenwood University

8.6/10 (183 reviews)

Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St Charles Convention Center

8.4/10 (223 reviews)

After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.

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Frequently asked questions

What's the area like around Historic Main Street?

Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 103 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Historic Main Street?

Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.

How many hotels are there near Historic Main Street?

Expedia has 103 hotels and other accommodations within a mile from Historic Main Street.

If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.

Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?

For more information about rescheduling or cancelling your stay near Historic Main Street, click here.

What can I see and do near Historic Main Street?

Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

Find hotels near Historic Main Street, St. Louis from SAR 310

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Treat yourself

Be picky

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Our top choices for Historic Main Street hotels

1. Country Inn & Suites by Radisson, St. Charles Historic District

2. Hollywood Casino & Hotel St. Louis

3. Ameristar Casino Resort and Spa

4. Tru by Hilton St. Charles St. Louis, MO

5. Comfort Suites St Charles - St Louis

6. Elimwood Hotel, a Ramada by Wyndham

7. Holiday Inn St. Louis Arpt West-Earth City by IHG

8. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

9. Drury Plaza Hotel St. Louis Chesterfield

10. Drury Inn & Suites St. Louis St. Peters

11. Hyatt Place St. Louis/Chesterfield

12. Pear Tree Inn St. Louis Airport

13. Wingate by Wyndham St. Louis Airport

14. Residence Inn by Marriott St. Louis Chesterfield

15. Hyatt Select St. Louis Airport

16. Holiday Inn Express & Suites St Peters by IHG

17. Fairfield Inn & Suites St Louis Westport

18. Hampton Inn By Hilton St Louis Airport

19. SpringHill Suites by Marriott St. Louis Chesterfield

20. Drury Plaza Hotel St. Louis Creve Coeur

Compare popular hotels close to Historic Main Street

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

Riverwood Retreat | Main Street 2BR

The Oak & Aura Retreat

The St. Charles Guest House, lovely historic home, fun for families and groups

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

The Rustic Revival | Charming 2BR Retreat

Driftwood Den | Boho 2BR | Dog-Friendly

Main Street 2BR - Walk to Dining & Riverfront

The Foundry Flat | Industrial-Inspired 2-Bedroom

Other attractions near Historic Main Street

Frontier Park

Katy Trail

First Missouri State Capitol Historic Site

Missouri Artists on Main

Lewis & Clark Boathouse and Nature Center

Frenchtown Heritage Museum

Lindenwood University

St Charles Convention Center

Frequently asked questions