A brick-paved street lined with historic buildings and a yellow fire hydrant.

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5 Sep - 6 Sep
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6 Sep - 7 Sep
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11 Sep - 13 Sep
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18 Sep - 20 Sep

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Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
1.8 km from Historic Main Street
United States
Robert
SAR 544
SAR 631 total
includes taxes & fees
13 Sep - 14 Sep
Drury Plaza Hotel St. Louis St. Charles

2. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
St. Charles Historic District, 1 km from Historic Main Street
United States
Susan Greening.
SAR 510
SAR 586 total
includes taxes & fees
4 Oct - 5 Oct
Country Inn & Suites by Radisson, St. Charles Historic District

3. Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
1.5 km from Historic Main Street
United Kingdom
Nicola
SAR 428
SAR 515 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites St. Charles Old Town Area

4. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
2.1 km from Historic Main Street
United States
Denise
SAR 520
SAR 598 total
includes taxes & fees
13 Sep - 14 Sep
Embassy Suites by Hilton St. Louis St. Charles

5. Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.1 km from Historic Main Street
United States
Denise
SAR 459
SAR 532 total
includes taxes & fees
13 Sep - 14 Sep
Tru by Hilton St. Charles St. Louis, MO

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
1.4 km from Historic Main Street
United States
Tracey
SAR 589
SAR 750 total
includes taxes & fees
21 Sep - 22 Sep
Ameristar Casino Resort and Spa

7. Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3 km from Historic Main Street
United States
Glenda
SAR 351
SAR 521 total
includes taxes & fees
5 Oct - 6 Oct
Hollywood Casino & Hotel St. Louis

8. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
1.5 km from Historic Main Street
United States
Bryan
SAR 312
SAR 359 total
includes taxes & fees
4 Oct - 5 Oct
Comfort Suites St Charles - St Louis

9. Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
1.5 km from Historic Main Street
United States
Melisa
SAR 316
SAR 366 total
includes taxes & fees
9 Sep - 10 Sep
Best Western Plus The Charles Hotel

10. Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
3.1 km from Historic Main Street
United States
Jasmine
SAR 312
SAR 362 total
includes taxes & fees
8 Sep - 9 Sep
Elimwood Hotel, a Ramada by Wyndham

11. Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
2.9 km from Historic Main Street
United States
Bryan
SAR 413
SAR 475 total
includes taxes & fees
9 Sep - 10 Sep
Holiday Inn St. Louis Arpt West-Earth City by IHG

12. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
1.6 km from Historic Main Street
United States
Tom
SAR 338
SAR 392 total
includes taxes & fees
6 Sep - 7 Sep
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

13. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
12 km from Historic Main Street
United States
Paige
SAR 413
SAR 508 total
includes taxes & fees
20 Sep - 21 Sep
Hyatt Select St. Louis Airport

14. Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
11.3 km from Historic Main Street
United States
Jeff
SAR 432
SAR 507 total
includes taxes & fees
27 Sep - 28 Sep
Drury Inn & Suites St. Louis Airport

15. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
10.7 km from Historic Main Street
United States
Margaret
SAR 415
SAR 489 total
includes taxes & fees
14 Sep - 15 Sep
Wingate by Wyndham St. Louis Airport

16. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
10.6 km from Historic Main Street
United States
Darren
SAR 338
SAR 398 total
includes taxes & fees
9 Sep - 10 Sep
Pear Tree Inn St. Louis Airport

17. Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport
11.7 km from Historic Main Street
United States
Carrie
SAR 515
SAR 614 total
includes taxes & fees
20 Sep - 21 Sep
Hampton Inn By Hilton St Louis Airport

18. Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
9.5 km from Historic Main Street
United States
Deoshae
SAR 492
SAR 571 total
includes taxes & fees
13 Sep - 14 Sep
Fairfield Inn & Suites St Louis Westport

19. Residence Inn St Louis Westport

Residence Inn St Louis Westport
9.5 km from Historic Main Street
United States
Satesh
SAR 605
SAR 702 total
includes taxes & fees
13 Sep - 14 Sep
Residence Inn St Louis Westport

20. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
15.9 km from Historic Main Street
United States
Jolisa
SAR 439
SAR 509 total
includes taxes & fees
13 Sep - 14 Sep
Hyatt Place St. Louis/Chesterfield
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Compare popular hotels close to Historic Main Street

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Lobby
Drury Plaza Hotel St. Louis St. Charles
9.6
Exceptional
1,003 reviews
View
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District
9.4
Exceptional
1,076 reviews
View
Free daily buffet breakfast
Hampton Inn & Suites St. Charles Old Town Area
9.0
Wonderful
731 reviews
View
Lobby
Embassy Suites by Hilton St. Louis St. Charles
8.8
Excellent
1,000 reviews
View
Exterior
Tru by Hilton St. Charles St. Louis, MO
8.6
Excellent
863 reviews
View

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

8/10 Good
"Room was clean Pillows not comfy There was no cold water-odd as no hot water is the common problem with water but too hot to take a shower !!!"
Mary 1-night trip
Posted 10 hours ago
Ameristar Casino Resort and Spa
Driftwood Den | Boho 2BR | Dog-Friendly

Driftwood Den | Boho 2BR | Dog-Friendly

10/10 Excellent
"Clean, easy parking, easy egress and ingress"
Rachel M. 5-night trip
Posted 10 days ago
Driftwood Den | Boho 2BR | Dog-Friendly
Stylish 2BR Retreat - Concrete & Canopy

Stylish 2BR Retreat - Concrete & Canopy

10/10 Excellent
"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"
Billi G. 2-night trip
Posted 10 days ago
Stylish 2BR Retreat - Concrete & Canopy
The Foundry Flat | Industrial-Inspired 2-Bedroom

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent
"Everything was exactly as described. St. Charles is an awesome place!"
Michael 2-night trip
Posted 11 days ago
The Foundry Flat | Industrial-Inspired 2-Bedroom
The Global Getaway | World-Inspired 2-Bedroom Stay

The Global Getaway | World-Inspired 2-Bedroom Stay

10/10 Excellent
"Perfect location to Main Street.Hosts were easy to communicate with.No issues with the unit"
Tony M. 4-night trip
Posted 12 days ago
The Global Getaway | World-Inspired 2-Bedroom Stay
The Rustic Revival | Charming 2BR Retreat

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent
"The property is very conveniently located to shops and restaurants on Main Street of the St Charles Historic District. The area feels very safe and locals were friendly."
Terry H. 4-night trip
Posted 2 weeks ago
The Rustic Revival | Charming 2BR Retreat
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

10/10 Excellent
"The home was very inviting! All of the hosts extra touches so appreciated (coffee pods, snacks, etc). Beds were comfortable and all necessities were available. A wonderful stay! We will definitely return."
Cathilynne F. 3-night trip
Posted 3 weeks ago
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

10/10 Excellent
"This is a great little gem in the heart of the historic district. The hosts communicated very well and often. The location is within walking distance of many restaurants and activities. I would stay here again."
Debbie R. 4-night trip
Posted 3 weeks ago
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
The St. Charles Guest House, lovely historic home, fun for families and groups

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent
"The location of the house was fabulous. You are literally steps from the Main Street of historic St. Charles. Walking distance to several restaurants, shops, dessert stops and coffee shops. We also enjoyed the greater St Charles area and it was a quick drive into St Louis.The house is well stocked (could use some more towels) with a nice kitchen area. We enjoyed the game room and living room reading corner. Love being able to come home with clean clothes so appreciate the washer and dryer.We hit St Charles during a heat wave and the house really struggled to get cooler than 75 degrees. We also didn’t realize how many steps there were throughout the house. The staircase upstairs is fairly steep. To get to the master bedroom one must maneuver several steps and climb from the steps into the bed. We were fine just wanted to give others the heads up if accessibility was an issue.We truly enjoyed the St Charles area and hope to visit again soon!"
Erin T. 4-night trip
Posted 1 month ago
The St. Charles Guest House, lovely historic home, fun for families and groups

Other attractions near Historic Main Street

A person holding a guitar.
Photo by HA

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.
See properties
A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
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First Missouri State Capitol Historic Site

8.2/10 (25 reviews)
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.
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Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)
You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.
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Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
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Lindenwood University

8.6/10 (183 reviews)
Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.
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St Charles Convention Center

8.4/10 (223 reviews)
After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 106 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Historic Main Street?
Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Hollywood Casino & Hotel St. Louis, located 1.8 mi (3 km) away.
How many hotels are there near Historic Main Street?
Expedia has 106 hotels and other accommodations within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.
Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?
For more information about rescheduling or cancelling your stay near Historic Main Street, click here.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.