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18 Sep - 20 Sep Our top choices for Historic Main Street hotels




1. Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles1.8 km from Historic Main Street
Robert
SAR 544
SAR 631 total
includes taxes & fees
13 Sep - 14 Sep




2. Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic DistrictSt. Charles Historic District, 1 km from Historic Main Street
Susan Greening.
SAR 469
SAR 539 total
includes taxes & fees
4 Oct - 5 Oct




3. Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area1.5 km from Historic Main Street
Daniel
SAR 428
SAR 515 total
includes taxes & fees
4 Oct - 5 Oct




4. Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles2.1 km from Historic Main Street
Denise
SAR 520
SAR 598 total
includes taxes & fees
27 Sep - 28 Sep




5. Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa1.4 km from Historic Main Street
Tracey
SAR 589
SAR 750 total
includes taxes & fees
22 Sep - 23 Sep




6. Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis3 km from Historic Main Street
Nicole
SAR 378
SAR 552 total
includes taxes & fees
5 Oct - 6 Oct




7. Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis1.5 km from Historic Main Street
Bryan
SAR 300
SAR 345 total
includes taxes & fees
14 Sep - 15 Sep




8. Best Western Plus The Charles Hotel
Best Western Plus The Charles Hotel1.5 km from Historic Main Street
Melisa
SAR 316
SAR 366 total
includes taxes & fees
13 Sep - 14 Sep




9. Elimwood Hotel, a Ramada by Wyndham
Elimwood Hotel, a Ramada by Wyndham3.1 km from Historic Main Street
Jasmine
SAR 312
SAR 362 total
includes taxes & fees
10 Sep - 11 Sep




10. Holiday Inn St. Louis Arpt West-Earth City by IHG
Holiday Inn St. Louis Arpt West-Earth City by IHG2.9 km from Historic Main Street
Bryan
SAR 413
SAR 475 total
includes taxes & fees
20 Sep - 21 Sep




11. Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles Inn1.6 km from Historic Main Street
Tom
SAR 300
SAR 348 total
includes taxes & fees
10 Sep - 11 Sep




12. Hyatt Select St. Louis Airport
Hyatt Select St. Louis Airport12 km from Historic Main Street
Paige
SAR 413
SAR 508 total
includes taxes & fees
27 Sep - 28 Sep




13. Drury Inn & Suites St. Louis Airport
Drury Inn & Suites St. Louis Airport11.3 km from Historic Main Street
Jeff
SAR 432
SAR 507 total
includes taxes & fees
27 Sep - 28 Sep




14. Wingate by Wyndham St. Louis Airport
Wingate by Wyndham St. Louis Airport10.7 km from Historic Main Street
Margaret
SAR 415
SAR 489 total
includes taxes & fees
15 Sep - 16 Sep




15. Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport10.6 km from Historic Main Street
Monica
SAR 338
SAR 398 total
includes taxes & fees
21 Sep - 22 Sep




16. Hampton Inn By Hilton St Louis Airport
Hampton Inn By Hilton St Louis Airport11.7 km from Historic Main Street
Danielle
SAR 515
SAR 614 total
includes taxes & fees
20 Sep - 21 Sep




17. Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria Area18.7 km from Historic Main Street
Carlos
SAR 490
SAR 576 total
includes taxes & fees
13 Sep - 14 Sep




18. Fairfield Inn & Suites St Louis Westport
Fairfield Inn & Suites St Louis Westport9.5 km from Historic Main Street
Deoshae
SAR 492
SAR 571 total
includes taxes & fees
13 Sep - 14 Sep




19. Hyatt Place St. Louis/Chesterfield
Hyatt Place St. Louis/Chesterfield15.9 km from Historic Main Street
Jolisa
SAR 392
SAR 454 total
includes taxes & fees
13 Sep - 14 Sep




20. Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis Chesterfield15.8 km from Historic Main Street
Cassandra
SAR 488
SAR 566 total
includes taxes & fees
22 Sep - 23 Sep
Compare popular hotels close to Historic Main Street
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included |
|---|---|---|---|---|---|---|---|
![]() Drury Plaza Hotel St. Louis St. Charles | 9.6 Exceptional 1,007 reviews | View | |||||
![]() Country Inn & Suites by Radisson, St. Charles Historic District | 9.4 Exceptional 1,082 reviews | View | |||||
![]() Hampton Inn & Suites St. Charles Old Town Area | 9.0 Wonderful 733 reviews | View | |||||
![]() Embassy Suites by Hilton St. Louis St. Charles | 8.8 Excellent 1,000 reviews | View | |||||
![]() Ameristar Casino Resort and Spa | 8.6 Excellent 1,045 reviews | View |
Top Historic Main Street Hotel Reviews
Ameristar Casino Resort and Spa
10/10 Excellent
"I'll tell you what. I visited the Ameristar for a fun weekend reunion with a long time college friend I hadn't seen in 30 years. We had plans to see the city, eat Italian on the Hill, go see the arch, see the city museum. But no...we left one time to go to a diner around the corner for breakfast and realized we had no desire to leave the hotel again. The food was amazing, the people (most likely regulars) were hilarious and fun. The pool was to die for. The bartenders at the pool were amazing and fun. We went to see the cover band at one of the bars on Saturday night and the place was PACKED. I think people were there just to go see them. Costumes, mullet wigs, 90's hair band...it was so fun. Will most DEFINITELY be back. Can't say enough good things. The rooms were HUGE and lovely. There were 17 pillows to choose from for your firmness desire (okay, maybe just 4 but still...). We had a blast."
The Rustic Revival | Charming 2BR Retreat
10/10 Excellent
"The Host ensured our needs were taken care. Perfect location!"
Driftwood Den | Boho 2BR | Dog-Friendly
10/10 Excellent
"Clean, easy parking, easy egress and ingress"
Stylish 2BR Retreat - Concrete & Canopy
10/10 Excellent
"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"
The Foundry Flat | Industrial-Inspired 2-Bedroom
10/10 Excellent
"Everything was exactly as described. St. Charles is an awesome place!"
The Global Getaway | World-Inspired 2-Bedroom Stay
10/10 Excellent
"Perfect location to Main Street.Hosts were easy to communicate with.No issues with the unit"
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
10/10 Excellent
"The home was very inviting! All of the hosts extra touches so appreciated (coffee pods, snacks, etc). Beds were comfortable and all necessities were available. A wonderful stay! We will definitely return."
The St. Charles Guest House, lovely historic home, fun for families and groups
10/10 Excellent
"The location of the house was fabulous. You are literally steps from the Main Street of historic St. Charles. Walking distance to several restaurants, shops, dessert stops and coffee shops. We also enjoyed the greater St Charles area and it was a quick drive into St Louis.The house is well stocked (could use some more towels) with a nice kitchen area. We enjoyed the game room and living room reading corner. Love being able to come home with clean clothes so appreciate the washer and dryer.We hit St Charles during a heat wave and the house really struggled to get cooler than 75 degrees. We also didn’t realize how many steps there were throughout the house. The staircase upstairs is fairly steep. To get to the master bedroom one must maneuver several steps and climb from the steps into the bed. We were fine just wanted to give others the heads up if accessibility was an issue.We truly enjoyed the St Charles area and hope to visit again soon!"
Hearth & Harvest | Historic St. Charles 2BR
10/10 Excellent
"This is one place that I would book again and again. Yes, however, the one-bedroom is on the main street, so there's outside noise, but I'm thankful to have a TV to drown out some of the chatter and music from outside. High ceilings great vibes."
Other attractions near Historic Main Street
Photo by HA
Frontier Park
You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.

Katy Trail
9.0/10 (158 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
First Missouri State Capitol Historic Site
8.2/10 (25 reviews)
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.
Missouri Artists on Main
You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
Lewis & Clark Boathouse and Nature Center
8.8/10 (113 reviews)
You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
Frenchtown Heritage Museum
You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
Lindenwood University
8.6/10 (183 reviews)
Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.
St Charles Convention Center
8.4/10 (223 reviews)
After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.




