The Best Hotels Closest to Historic Main Street in St. Louis for 2026

A brick-paved street lined with historic buildings and a yellow fire hydrant.

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Our top choices for Historic Main Street hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

1. Drury Plaza Hotel St. Louis St. Charles

1.8 km from Historic Main Street

Robert

SAR 544

SAR 631 total

includes taxes & fees

25 Oct - 26 Oct

A brick building with a sign reading "Country Inn & Suites."

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

A spacious living room with a blue sofa, a white coffee table, and a striped armchair. There is a bookshelf filled with decorative items and a television on a wooden stand.

2. Country Inn & Suites by Radisson, St. Charles Historic District

St. Charles Historic District, 1 km from Historic Main Street

Stewart

SAR 489

SAR 562 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with a central island, breakfast bar, and various appliances.

An indoor swimming pool with blue walls, a tiled floor, and lounge chairs.

A hotel room with a large bed, a desk, a chair, and a window with a view.

A modern hotel reception area with a receptionist desk, a large welcome sign, and a view of the cityscape through the glass doors.

3. Hampton Inn & Suites St. Charles Old Town Area

1.5 km from Historic Main Street

Sara

SAR 478

SAR 573 total

includes taxes & fees

19 Nov - 20 Nov

A large hotel with a prominent tower and multiple parking areas.

A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.

A bar area with a long counter, multiple screens, and seating.

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

4. Hollywood Casino & Hotel St. Louis

3 km from Historic Main Street

Lindsay

SAR 354

SAR 471 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

A bar area with multiple seating arrangements, a stage, and a chandelier.

A bakery display case with various pastries and cakes.

A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

5. Ameristar Casino Resort and Spa

1.4 km from Historic Main Street

Melissa

SAR 597

SAR 760 total

includes taxes & fees

16 Nov - 17 Nov

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

6. Comfort Suites St Charles - St Louis

1.5 km from Historic Main Street

Bryan

SAR 363

SAR 417 total

includes taxes & fees

2 Nov - 3 Nov

A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

A spacious living room with a modern chandelier, a fireplace, and a large television on the wall.

A hotel room with a large bed, bedside tables with lamps, a flat-screen TV, and a large window with curtains.

A spacious room with multiple tables and chairs, a reception desk, and a counter with various items.

7. Best Western Plus The Charles Hotel

1.5 km from Historic Main Street

Tony

SAR 348

SAR 403 total

includes taxes & fees

27 Oct - 28 Oct

A modern kitchen with white cabinets, a long countertop, and overhead lighting.

A hotel room with two beds, a desk with a television, a microwave, and a small refrigerator.

8. Elimwood Hotel, a Ramada by Wyndham

3.1 km from Historic Main Street

Lucas

SAR 238

SAR 279 total

includes taxes & fees

3 Nov - 4 Nov

A restaurant with a long wooden table, cushioned seating, and decorative lanterns.

A hotel room with a kitchenette, a sofa, a desk, and a large window with curtains.

A lobby with a checkered floor, a sofa, armchairs, a small table, and a water dispenser.

A compact kitchen with dark wooden cabinets, a built-in microwave, and a stainless steel refrigerator.

9. Holiday Inn St. Louis Arpt West-Earth City by IHG

2.9 km from Historic Main Street

Bryan

SAR 349

SAR 405 total

includes taxes & fees

25 Oct - 26 Oct

A shower with grab bars and a towel rack.

A hotel room with a large bed, two bedside lamps, a nightstand with a phone and alarm clock, and two framed floral pictures on the wall.

A lobby with a fireplace, several potted plants, a television, and a sofa.

A spacious lobby with a reception desk, seating area, and a fireplace.

10. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1.6 km from Historic Main Street

Gonzalo

SAR 338

SAR 391 total

includes taxes & fees

21 Oct - 22 Oct

An outdoor patio with a built-in grill, seating area, and stone walls.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

A multi-story hotel with a parking lot in front.

A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

11. Residence Inn by Marriott St. Louis Chesterfield

15.1 km from Historic Main Street

Chelsea

SAR 709

SAR 830 total

includes taxes & fees

27 Oct - 28 Oct

A spacious lobby with a central round table, two sofas, and a chandelier.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

12. Drury Plaza Hotel St. Louis Chesterfield

15.8 km from Historic Main Street

Chasity

SAR 485

SAR 563 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

13. Pear Tree Inn St. Louis Airport

10.6 km from Historic Main Street

Brittany

SAR 320

SAR 380 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

14. Wingate by Wyndham St. Louis Airport

10.7 km from Historic Main Street

Rachal

SAR 363

SAR 431 total

includes taxes & fees

28 Oct - 29 Oct

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

15. Hyatt Place St. Louis/Chesterfield

15.9 km from Historic Main Street

Debbie

SAR 453

SAR 525 total

includes taxes & fees

25 Oct - 26 Oct

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel reception area with a counter, seating, and a staircase.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A pool area with two hot tubs, seating, and a view of the outdoors.

16. Drury Inn & Suites St. Louis Airport

11.3 km from Historic Main Street

Ethan

SAR 410

SAR 485 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A modern lobby with blue seating, a reception desk, and large windows.

17. Hyatt Select St. Louis Airport

12 km from Historic Main Street

Daisy

SAR 413

SAR 512 total

includes taxes & fees

29 Oct - 30 Oct

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A modern lobby with a reception desk, seating area, and a dining section.

A Holiday Inn Express hotel with a modern design, featuring a covered entrance and multiple windows.

18. Holiday Inn Express & Suites St Peters by IHG

15.7 km from Historic Main Street

Serah

SAR 443

SAR 532 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with a table and chairs, a fire feature, and a brick wall.

A bar area with a counter, stools, and shelves with bottles and glasses.

A hotel lobby with a seating area, tables, and a TV screen.

A hotel room with a bed, bedside tables, a wardrobe, and a window with curtains.

19. SpringHill Suites by Marriott St. Louis Chesterfield

15.4 km from Historic Main Street

Jamie

SAR 459

SAR 532 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A snack vending machine with various snack options.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

20. Hampton Inn By Hilton St Louis Airport

11.7 km from Historic Main Street

Judith

SAR 428

SAR 515 total

includes taxes & fees

19 Nov - 20 Nov

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Compare popular hotels close to Historic Main Street

Property	Property class	Guest rating
Drury Plaza Hotel St. Louis St. Charles	9.6 Exceptional 1,004 reviews	View
Country Inn & Suites by Radisson, St. Charles Historic District	9.4 Exceptional 1,107 reviews	View
Hampton Inn & Suites St. Charles Old Town Area	9.0 Wonderful 751 reviews	View
Hollywood Casino & Hotel St. Louis	8.6 Excellent 2,230 reviews	View
Ameristar Casino Resort and Spa	8.6 Excellent 1,080 reviews	View

Top Historic Main Street Hotel Reviews

Riverwood Retreat | Main Street 2BR

10/10 Excellent

"Very Good apt! Near everything!"

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

10/10 Excellent

"The rental is small but it worked perfectly for 3. The beds are very comfortable. I was a little worried about the twin beds upstairs- but they were comfortable as well!The location is perfect for strolling around St. Charles historic district. We could shop, drop off bags and head out for more shopping.Very easy checkout."

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent

"Perfect downtown stay! Lots of shopping, food and bars within walking distance. Love that the rooms had a sound machine!"

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

10/10 Excellent

"Beautiful place and close to shops and dining!"

The Oak & Aura Retreat

10/10 Excellent

"The room was great. Very good location for the Oktoberfest. Very clean. We love the stay great communications."

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent

"They were excellent hosts and great communication!! I highly recommend this house!"

Main Street 2BR - Walk to Dining & Riverfront

10/10 Excellent

"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"

The Fox Den Suite — Cozy, playful, and memorable.

8/10 Good

"Great place right on Main Street. Bed was very comfortable. Couch is like a mini couch, very low to the ground and not what’s in the listing picture. As others have mentioned it is very noisy on Friday and Saturday nights with the bar next door. Parking was a little chaotic due to the craft show going on all weekend, but not the hosts fault. It would be nice if there was reserved parking for those staying at the Outter. Overall the place is cute, clean, comfortable bed, and great bathroom."

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent

"Everything was exactly as described. St. Charles is an awesome place!"

Other attractions near Historic Main Street

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.

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A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)

You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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First Missouri State Capitol Historic Site

8.2/10 (25 reviews)

You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.

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Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)

You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lindenwood University

8.6/10 (183 reviews)

Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St Charles Convention Center

8.4/10 (223 reviews)

After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.

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Frequently asked questions

What's the area like around Historic Main Street?

Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 103 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Historic Main Street?

Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.

How many hotels are there near Historic Main Street?

Expedia has 103 hotels and other accommodations within a mile from Historic Main Street.

If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.

Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?

For more information about rescheduling or cancelling your stay near Historic Main Street, click here.

What can I see and do near Historic Main Street?

Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

Find hotels near Historic Main Street, St. Louis from SAR 279

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Treat yourself

Be picky

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Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

2. Country Inn & Suites by Radisson, St. Charles Historic District

3. Hampton Inn & Suites St. Charles Old Town Area

4. Hollywood Casino & Hotel St. Louis

5. Ameristar Casino Resort and Spa

6. Comfort Suites St Charles - St Louis

7. Best Western Plus The Charles Hotel

8. Elimwood Hotel, a Ramada by Wyndham

9. Holiday Inn St. Louis Arpt West-Earth City by IHG

10. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

11. Residence Inn by Marriott St. Louis Chesterfield

12. Drury Plaza Hotel St. Louis Chesterfield

13. Pear Tree Inn St. Louis Airport

14. Wingate by Wyndham St. Louis Airport

15. Hyatt Place St. Louis/Chesterfield

16. Drury Inn & Suites St. Louis Airport

17. Hyatt Select St. Louis Airport

18. Holiday Inn Express & Suites St Peters by IHG

19. SpringHill Suites by Marriott St. Louis Chesterfield

20. Hampton Inn By Hilton St Louis Airport

Compare popular hotels close to Historic Main Street

Top Historic Main Street Hotel Reviews

Riverwood Retreat | Main Street 2BR

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

The Rustic Revival | Charming 2BR Retreat

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

The Oak & Aura Retreat

The St. Charles Guest House, lovely historic home, fun for families and groups

Main Street 2BR - Walk to Dining & Riverfront

The Fox Den Suite — Cozy, playful, and memorable.

The Foundry Flat | Industrial-Inspired 2-Bedroom

Other attractions near Historic Main Street

Frontier Park

Katy Trail

First Missouri State Capitol Historic Site

Missouri Artists on Main

Lewis & Clark Boathouse and Nature Center

Frenchtown Heritage Museum

Lindenwood University

St Charles Convention Center

Frequently asked questions