The Best Hotels Closest to Historic Main Street in St. Louis for 2026

A brick-paved street lined with historic buildings and a yellow fire hydrant.

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Our top choices for Historic Main Street hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A gym with treadmills, stationary bikes, and a weight machine.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

1. Drury Plaza Hotel St. Louis St. Charles

1.8 km from Historic Main Street

Robert

SAR 518

SAR 601 total

includes taxes & fees

12 Oct - 13 Oct

A large hotel with a prominent tower and multiple parking areas.

A bar area with a long counter, multiple screens, and seating.

A crowded indoor space with a chandelier, brick walls, and tables where people are seated and standing.

A lobby with a large screen displaying "Hollywood Casino" and "Wood Casino" signs, multiple chandeliers, and a polished floor.

2. Hollywood Casino & Hotel St. Louis

3 km from Historic Main Street

Nicole

SAR 313

SAR 480 total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor lobby with multiple seating areas, including round tables and sofas, and a central water feature.

A multi-story hotel with a central courtyard, a parking lot, and a green-roofed building.

A grand staircase with a wooden railing leading to a lower level, surrounded by potted plants and a patterned carpet.

A hotel room with a sofa, armchairs, a coffee table, a desk, and a large window with curtains.

3. Embassy Suites by Hilton St. Louis St. Charles

2.1 km from Historic Main Street

Anonymous traveler

SAR 520

SAR 598 total

includes taxes & fees

12 Oct - 13 Oct

A modern lounge area with sofas, tables, and chairs, featuring a mix of seating arrangements and a central coffee station.

A modern cafe with a self-serve beverage station, a central island with seating, and large windows offering a view.

A modern lounge area with seating arrangements, tables, and hanging pendant lights.

4. Tru by Hilton St. Charles St. Louis, MO

2.1 km from Historic Main Street

Meridith

SAR 459

SAR 532 total

includes taxes & fees

11 Oct - 12 Oct

A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

A hotel lobby with a wooden floor, a reception desk, two armchairs, a sofa, and large windows with a view of buildings outside.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A spacious lobby with a reception desk, a seating area with a sofa, a vending machine, and a wall-mounted clock.

5. Comfort Suites St Charles - St Louis

1.5 km from Historic Main Street

Bryan

SAR 371

SAR 426 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with white cabinets, a long countertop, and overhead lighting.

A spacious lobby with a modern design, featuring a large seating area with sofas and chairs, a patterned carpet, and a view of the outside through large windows.

A hotel room with two beds, a desk with a television, a microwave, and a small refrigerator.

6. Elimwood Hotel, a Ramada by Wyndham

3.1 km from Historic Main Street

Rebecca

SAR 265

SAR 310 total

includes taxes & fees

2 Nov - 3 Nov

A restaurant with a long wooden table, cushioned seating, and decorative lanterns.

A hotel room with a kitchenette, a sofa, a desk, and a large window with curtains.

A lobby with a checkered floor, a sofa, armchairs, a small table, and a water dispenser.

A hotel room with two beds, a nightstand with a lamp, a framed picture on the wall, and a patterned carpet.

7. Holiday Inn St. Louis Arpt West-Earth City by IHG

2.9 km from Historic Main Street

Bryan

SAR 413

SAR 475 total

includes taxes & fees

29 Oct - 30 Oct

A spacious lobby with a reception desk, seating area, and a fireplace.

A hotel room with a large bed, two bedside lamps, a nightstand with a phone and alarm clock, and two framed floral pictures on the wall.

A lobby with a fireplace, several potted plants, a television, and a sofa.

A living room with a beige sofa, a wooden coffee table, a patterned rug, a potted plant, and two framed pictures on the wall.

8. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1.6 km from Historic Main Street

Tom

SAR 287

SAR 333 total

includes taxes & fees

12 Oct - 13 Oct

An outdoor patio with a built-in grill, seating area, and stone walls.

A multi-story hotel with a parking lot in front.

A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

9. Residence Inn by Marriott St. Louis Chesterfield

15.1 km from Historic Main Street

Chelsea

SAR 710

SAR 830 total

includes taxes & fees

15 Oct - 16 Oct

A spacious lobby with a central round table, two sofas, and a chandelier.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

10. Drury Plaza Hotel St. Louis Chesterfield

15.8 km from Historic Main Street

Cassandra

SAR 488

SAR 566 total

includes taxes & fees

15 Oct - 16 Oct

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

11. Hyatt Place St. Louis/Chesterfield

15.9 km from Historic Main Street

Chelsea

SAR 487

SAR 564 total

includes taxes & fees

5 Oct - 6 Oct

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

12. Pear Tree Inn St. Louis Airport

10.6 km from Historic Main Street

Murphy

SAR 338

SAR 398 total

includes taxes & fees

18 Oct - 19 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

13. Hyatt Select St. Louis Airport

12 km from Historic Main Street

Will

SAR 413

SAR 508 total

includes taxes & fees

20 Oct - 21 Oct

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A pool area with two hot tubs, seating, and a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

14. Drury Inn & Suites St. Louis Airport

11.3 km from Historic Main Street

Lakeshia

SAR 432

SAR 507 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

15. Wingate by Wyndham St. Louis Airport

10.7 km from Historic Main Street

Mary

SAR 363

SAR 428 total

includes taxes & fees

15 Oct - 16 Oct

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A snack vending machine with various snack options.

16. Hampton Inn By Hilton St Louis Airport

11.7 km from Historic Main Street

Leia

SAR 484

SAR 577 total

includes taxes & fees

15 Oct - 16 Oct

An outdoor patio area with wicker furniture and a central fire feature.

A Courtyard Marriott hotel with a parking lot and a green shuttle service.

A modern hotel lobby with a bar area, seating arrangements, and a reception desk.

A hotel room with a bed, a sofa, a desk, and a chair.

17. Courtyard by Marriott St. Louis Chesterfield

16.2 km from Historic Main Street

Kelly

SAR 436

SAR 507 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A Holiday Inn Express hotel with a modern design, featuring a covered entrance and multiple windows.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel room with two beds, a desk, a blue sofa, and a TV.

18. Holiday Inn Express & Suites St Peters by IHG

15.7 km from Historic Main Street

Serah

SAR 443

SAR 532 total

includes taxes & fees

25 Oct - 26 Oct

A modern lounge area with a stone fireplace, a blue sofa, and a small table.

A Fairfield Inn & Suites Marriott hotel entrance with a modern design, featuring a brick facade, a covered entrance area, and a clear sky in the background.

An indoor swimming pool with lounge chairs and tables, large windows, and a clock on the wall.

A modern lobby with a blue sofa, a reception desk, and a snack bar.

19. Fairfield Inn & Suites St Louis Westport

9.5 km from Historic Main Street

Alan

SAR 492

SAR 576 total

includes taxes & fees

8 Oct - 9 Oct

A hotel lobby with a tiled floor, white columns, a reception desk, and a view into the dining area.

A two-story house with a tiled roof, a covered porch, and a driveway leading to the entrance.

A spacious lobby with a reception desk, seating area, and a large window.

A hallway with an exit sign, a vending machine, and a door.

20. Motel 6 Hazelwood, MO

8.2 km from Historic Main Street

Stephen

SAR 217

SAR 265 total

includes taxes & fees

1 Nov - 2 Nov

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Compare popular hotels close to Historic Main Street

Property	Property class	Guest rating
Drury Plaza Hotel St. Louis St. Charles	9.6 Exceptional 1,003 reviews	View
Hollywood Casino & Hotel St. Louis	8.6 Excellent 2,221 reviews	View
Embassy Suites by Hilton St. Louis St. Charles	8.8 Excellent 1,002 reviews	View
Tru by Hilton St. Charles St. Louis, MO	8.6 Excellent 876 reviews	View
Comfort Suites St Charles - St Louis	8.4 Very good 1,004 reviews	View

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

10/10 Excellent

"Perfect place to stay, for a fun weekend. The pool was amazing!"

The St. Charles Guest House, lovely historic home, fun for families and groups

10/10 Excellent

"They were excellent hosts and great communication!! I highly recommend this house!"

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

8/10 Good

"Great accessibility to shops and restaurants"

The Rustic Revival | Charming 2BR Retreat

10/10 Excellent

"The Host ensured our needs were taken care. Perfect location!"

Driftwood Den | Boho 2BR | Dog-Friendly

10/10 Excellent

"Clean, easy parking, easy egress and ingress"

Main Street 2BR - Walk to Dining & Riverfront

10/10 Excellent

"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"

The Foundry Flat | Industrial-Inspired 2-Bedroom

10/10 Excellent

"Everything was exactly as described. St. Charles is an awesome place!"

The Global Getaway | World-Inspired 2-Bedroom Stay

10/10 Excellent

"Perfect location to Main Street.Hosts were easy to communicate with.No issues with the unit"

Historic Main Street St. Charles - 2BR

10/10 Excellent

"This is one place that I would book again and again. Yes, however, the one-bedroom is on the main street, so there's outside noise, but I'm thankful to have a TV to drown out some of the chatter and music from outside. High ceilings great vibes."

Other attractions near Historic Main Street

Frontier Park

You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this walkable area.

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A steel bridge over a calm river with lush greenery and trees in the background.

Katy Trail

9.0/10 (158 reviews)

You can take time to visit Katy Trail during your travels to St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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First Missouri State Capitol Historic Site

8.2/10 (25 reviews)

You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and acclaimed theater scene in this family-friendly area.

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Missouri Artists on Main

You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lewis & Clark Boathouse and Nature Center

8.8/10 (113 reviews)

You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.

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Frenchtown Heritage Museum

You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.

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Lindenwood University

8.6/10 (183 reviews)

Walk around the campus at Lindenwood University during your stay in St. Charles. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St Charles Convention Center

8.4/10 (223 reviews)

After visiting St Charles Convention Center, make a plan to see the other sights and activities in St. Charles. Discover the top-notch restaurants and great live music in this family-friendly area.

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Frequently asked questions

What's the area like around Historic Main Street?

Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 103 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Historic Main Street?

Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Another good option is Country Inn & Suites by Radisson, St. Charles Historic District, located just 0.6 mi (1 km) away.

How many hotels are there near Historic Main Street?

Expedia has 103 hotels and other accommodations within a mile from Historic Main Street.

If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer near Historic Main Street.

Where can I learn more about changing or cancelling my trip in the area near Historic Main Street?

For more information about rescheduling or cancelling your stay near Historic Main Street, click here.

What can I see and do near Historic Main Street?

Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main, and Historic Aircraft Restoration Museum, you'll experience some of the local culture.

Find hotels near Historic Main Street, St. Louis from SAR 265

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Historic Main Street hotels

1. Drury Plaza Hotel St. Louis St. Charles

2. Hollywood Casino & Hotel St. Louis

3. Embassy Suites by Hilton St. Louis St. Charles

4. Tru by Hilton St. Charles St. Louis, MO

5. Comfort Suites St Charles - St Louis

6. Elimwood Hotel, a Ramada by Wyndham

7. Holiday Inn St. Louis Arpt West-Earth City by IHG

8. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

9. Residence Inn by Marriott St. Louis Chesterfield

10. Drury Plaza Hotel St. Louis Chesterfield

11. Hyatt Place St. Louis/Chesterfield

12. Pear Tree Inn St. Louis Airport

13. Hyatt Select St. Louis Airport

14. Drury Inn & Suites St. Louis Airport

15. Wingate by Wyndham St. Louis Airport

16. Hampton Inn By Hilton St Louis Airport

17. Courtyard by Marriott St. Louis Chesterfield

18. Holiday Inn Express & Suites St Peters by IHG

19. Fairfield Inn & Suites St Louis Westport

20. Motel 6 Hazelwood, MO

Compare popular hotels close to Historic Main Street

Top Historic Main Street Hotel Reviews

Ameristar Casino Resort and Spa

The St. Charles Guest House, lovely historic home, fun for families and groups

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

The Rustic Revival | Charming 2BR Retreat

Driftwood Den | Boho 2BR | Dog-Friendly

Main Street 2BR - Walk to Dining & Riverfront

The Foundry Flat | Industrial-Inspired 2-Bedroom

The Global Getaway | World-Inspired 2-Bedroom Stay

Historic Main Street St. Charles - 2BR

Other attractions near Historic Main Street

Frontier Park

Katy Trail

First Missouri State Capitol Historic Site

Missouri Artists on Main

Lewis & Clark Boathouse and Nature Center

Frenchtown Heritage Museum

Lindenwood University

St Charles Convention Center

Frequently asked questions