Defiance, MO

Travel Guide

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri
Defiance
Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri
Defiance
Defiance
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is SAR 413 per night from Apr 12 to Apr 13
SAR 413
SAR 536 total
12 Apr - 13 Apr
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,200 reviews)
Everything way too expensive! No places for vending machines rooms wete ok just plain. I tjought thry would be more upgrsde being in a casino environment

Reviewed on 9 April 2026

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
The price is SAR 335 per night from Apr 12 to Apr 13
SAR 335
SAR 387 total
12 Apr - 13 Apr
includes taxes & fees
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,191 reviews)
Great breakfast, bed and room. A+

Reviewed on 9 April 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl Wildwood MO
The price is SAR 331 per night from Apr 13 to Apr 14
SAR 331
SAR 386 total
13 Apr - 14 Apr
includes taxes & fees
Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...
9.2/10 Wonderful! (1,629 reviews)
Place was absolutely amazing however there was a couple of angry geese acting like bouncers in front

Reviewed on 8 April 2026

The Wildwood Hotel
See all 873 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Authentic Log cabin with something for everyone!

Authentic Log cabin with something for everyone!

Marthasville MO
Book a stay at this golf cabin in Marthasville. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Garbs House and Boone Monument Village ...
9.6/10 Exceptional! (395 reviews)
This property was pure tranquility! Couldn’t have asked for a lovelier stay. We especially enjoyed feeding the fish and my doggies loved watching them eat from the deck. We definitely plan on staying again soon!

Reviewed on 5 April 2026

Authentic Log cabin with something for everyone!
St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!

St Charles MO
Book a stay at this family-friendly vacation home in St. Charles. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ameristar Casino St. ...
9.8/10 Exceptional! (148 reviews)
Very nice historical place

Reviewed on 22 March 2026

St. Charles 1860's Gem - Sleeps 6!
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

Saint Charles MO
Stay at this vacation home in St. Charles. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ameristar Casino St. Charles and Hollywood ...
9.8/10 Exceptional! (88 reviews)
Convenient location and great price.

Reviewed on 7 April 2026

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟
See all properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Union Station, St. Louis, MO

St. Louis Union Station

4/5(625 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

St. Louis Union Station
Busch Stadium

Busch Stadium

4.5/5(1,487 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
Gateway Arch

Gateway Arch

4.5/5(2,542 reviews)

Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.

Gateway Arch
Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.

Enterprise Center

4.5/5(494 reviews)

Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.

Enterprise Center
St. Louis Zoo

St. Louis Zoo

4.5/5(1,225 reviews)

Why not visit the animals who live at St. Louis Zoo and see why this is a popular attraction in St. Louis? Amble around the area's lush forest or attend a sporting event.

St. Louis Zoo
Forest Park

Forest Park

4.5/5(1,059 reviews)

After visiting Forest Park, make a plan to see the other sights and activities in St. Louis. Discover the area's entertainment choices and shops.

Forest Park

Cities near Defiance

St. Louis

St. Louis